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Database: UniProt
Entry: X6IX55_9RHIZ
LinkDB: X6IX55_9RHIZ
Original site: X6IX55_9RHIZ 
ID   X6IX55_9RHIZ            Unreviewed;       490 AA.
AC   X6IX55;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   16-JAN-2019, entry version 34.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=X730_10050 {ECO:0000313|EMBL:ESZ50088.1};
OS   Mesorhizobium sp. L103C565B0.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Phyllobacteriaceae; Mesorhizobium.
OX   NCBI_TaxID=1287094 {ECO:0000313|EMBL:ESZ50088.1, ECO:0000313|Proteomes:UP000020756};
RN   [1] {ECO:0000313|EMBL:ESZ50088.1, ECO:0000313|Proteomes:UP000020756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L103C565B0 {ECO:0000313|EMBL:ESZ50088.1,
RC   ECO:0000313|Proteomes:UP000020756};
RA   Porter S.S., Chang P.L., Conow C.A., Dunham J.P., Friesen M.L.;
RT   "Adaptive variation in the core and flexible genome of wild
RT   Mesorhizobia.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ESZ50088.1}.
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DR   EMBL; AYXB01000002; ESZ50088.1; -; Genomic_DNA.
DR   EnsemblBacteria; ESZ50088; ESZ50088; X730_10050.
DR   PATRIC; fig|381.8.peg.2006; -.
DR   Proteomes; UP000020756; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000020756};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117}.
FT   DOMAIN      181    308       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      396    465       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     189    196       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   490 AA;  54941 MW;  CDC4A13129069E80 CRC64;
     MAASNDAEQK FDRVKAQLKA RLGTEVYSSW FGRMKVAEAS RGIVRISVPT AFLRSWINGH
     YLDLIADLWK HEDPEILKIE MVVRTATRPA RNGVEPEVVP ARKMTKHTQT ALAAGTVGPG
     RMERAPAPRP GTPIESEFRH NVLGSPLDPR YTFGSFIEGP SNRVAFAAAK AVAESQSSSV
     RFNPLFLHAT VGLGKTHLLQ AIAAESLKQN PKSRVVYLTA EYFMWRFATA IRDNNALTLK
     EQLRDIDLLI IDDMQFLQGK SIQHEFCHLI NMLLDSAKQV VVAADRPPSE LESLEPRVRS
     RLNGGVALEM SAPDFAMRIG MLKLRLATAK VDDASLNISE EILNHVARTV TGSGRELEGA
     FNQLLFRQSF EPAITIDRID EILGHIYRSG EPKRVRIEDI QRIVARHYNV SKTELLSNRR
     TRTIVKPRQV AMYLSKVLTP RSLPEIGRRF GGRDHTTVLH AVRKIEDLSG VDNTLAQELE
     LLRRLINDQA
//
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