ID X6M517_RETFI Unreviewed; 422 AA.
AC X6M517;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=DNA-directed DNA polymerase alpha 1 {ECO:0000313|EMBL:ETO08557.1};
GN ORFNames=RFI_28830 {ECO:0000313|EMBL:ETO08557.1};
OS Reticulomyxa filosa.
OC Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC Reticulomyxidae; Reticulomyxa.
OX NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO08557.1, ECO:0000313|Proteomes:UP000023152};
RN [1] {ECO:0000313|EMBL:ETO08557.1, ECO:0000313|Proteomes:UP000023152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24332546;
RA Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL Curr. Biol. 0:0-0(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO08557.1}.
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DR EMBL; ASPP01024887; ETO08557.1; -; Genomic_DNA.
DR AlphaFoldDB; X6M517; -.
DR EnsemblProtists; ETO08557; ETO08557; RFI_28830.
DR OrthoDB; 5477697at2759; -.
DR Proteomes; UP000023152; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd05776; DNA_polB_alpha_exo; 1.
DR Gene3D; 3.30.70.2820; -; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR006133; DNA-dir_DNA_pol_B_exonuc.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR NCBIfam; TIGR00592; pol2; 1.
DR PANTHER; PTHR45861; DNA POLYMERASE ALPHA CATALYTIC SUBUNIT; 1.
DR PANTHER; PTHR45861:SF1; DNA POLYMERASE ALPHA CATALYTIC SUBUNIT; 1.
DR Pfam; PF03104; DNA_pol_B_exo1; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW DNA-directed DNA polymerase {ECO:0000313|EMBL:ETO08557.1};
KW Nucleotidyltransferase {ECO:0000313|EMBL:ETO08557.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000023152};
KW Transferase {ECO:0000313|EMBL:ETO08557.1}.
FT DOMAIN 11..284
FT /note="DNA-directed DNA polymerase family B exonuclease"
FT /evidence="ECO:0000259|Pfam:PF03104"
FT REGION 396..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 422 AA; 49931 MW; D67817AF51409E9F CRC64;
MKVYGEIEQI RRKLGVSKWM CRPKKMKYCF RERKVIPFET EYLQVRYGYQ FDPIDPENSG
ETYEAVLGSR SSALELLLLD KDIMGPCWIR VPYEIKKEGE TNKYSWCKLE IELEDSYDRI
EVAIGNFQSP DLKILSLSLQ TTLDEKNNTK LHVYVHVFTI KKIDLNPFPY NLENELKEKQ
FDINRLKTFG TETEMLNYFS AELKEWDCDI IVGHKLFDFV LDVLFDRMDK LRTKHWSRIG
RLRRLKMPFL GGRLMKKSLG CGRLLCDTFL SAQEFIHQNT YTLSHLVKTQ LGISNYQNID
INKIKEYWLD GKQLAEIIRH CIVDGSLIAK IMFKLQILPL TKALTILCGN VWQRSLISQR
AERNEYLLLH EFHRAGFITP EKYTMNEKFN KHIIDENYND NDNDNQNKNN KKKEKNHNIL
VV
//
