ID   X6M6H5_RETFI            Unreviewed;       530 AA.
AC   X6M6H5;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN   ORFNames=RFI_28754 {ECO:0000313|EMBL:ETO08630.1};
OS   Reticulomyxa filosa.
OC   Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC   Reticulomyxidae; Reticulomyxa.
OX   NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO08630.1, ECO:0000313|Proteomes:UP000023152};
RN   [1] {ECO:0000313|EMBL:ETO08630.1, ECO:0000313|Proteomes:UP000023152}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24332546;
RA   Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA   Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA   Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT   "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL   Curr. Biol. 0:0-0(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETO08630.1}.
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DR   EMBL; ASPP01024851; ETO08630.1; -; Genomic_DNA.
DR   AlphaFoldDB; X6M6H5; -.
DR   EnsemblProtists; ETO08630; ETO08630; RFI_28754.
DR   OrthoDB; 2970398at2759; -.
DR   Proteomes; UP000023152; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   CDD; cd00009; AAA; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR031248; RNF213.
DR   PANTHER; PTHR22605:SF1; RZ-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR22605; UNCHARACTERIZED; 1.
DR   Pfam; PF00004; AAA; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000023152};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        55..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          172..294
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   REGION          105..128
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        106..128
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   530 AA;  61937 MW;  BCDE44AEF32968DA CRC64;
     MFLSESISIL LSDIKKMEGN KLQALKGQGF YLFDWQQDWK NKESALQVCN TYTHMYTYFA
     MCMYISVLFC CFFLKSRIKT SEMKSEKEQR LRVLFRILGT QYKETQKNQK ENKQNKSETK
     EEKKDEENSI VKTARLHDEI VKTLCEDTEW SNYVLTFDNI LKMVAIFLKV RTNTPIILMG
     ETGCGKTSLI KCLGHAANVN LVSIDVHGGF DKDELRKVIN DCSKKVSTDL DQELWLFLDE
     INTSPDIGWF KELICDHSLD GVKVSPQIKV IAACNPYRQR KVKASERTNT NDYLNKWVYR
     VFPMCETMKE YIWPFGQLNL LDEKKYIWAM TKQMKEKFES TSLAYKEIEQ WETVIAESIS
     KSQEFLRPTL ANEAIISLRD ASRCLKFFHW LMQHRHEGIT VKGQPISWIE RALNIALSLS
     YYFRLDEAQR KKYSQVMSSS KIPWFSDMVN EEITLLSESF QKPAQVAFHK ILKENLFVLF
     FCIVTETPMI LVGEPGTSKT LSLRIVLDTL SYHNINDFHQ KLKTIISYFA
//