ID X6MNP9_RETFI Unreviewed; 601 AA.
AC X6MNP9;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Guanylate cyclase domain-containing protein {ECO:0000259|PROSITE:PS50125};
GN ORFNames=RFI_21901 {ECO:0000313|EMBL:ETO15464.1};
OS Reticulomyxa filosa.
OC Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC Reticulomyxidae; Reticulomyxa.
OX NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO15464.1, ECO:0000313|Proteomes:UP000023152};
RN [1] {ECO:0000313|EMBL:ETO15464.1, ECO:0000313|Proteomes:UP000023152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24332546;
RA Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL Curr. Biol. 0:0-0(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO15464.1}.
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DR EMBL; ASPP01019101; ETO15464.1; -; Genomic_DNA.
DR AlphaFoldDB; X6MNP9; -.
DR EnsemblProtists; ETO15464; ETO15464; RFI_21901.
DR OrthoDB; 2876337at2759; -.
DR Proteomes; UP000023152; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR45655; GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2; 1.
DR PANTHER; PTHR45655:SF13; SOLUBLE GUANYLATE CYCLASE GCY-35-RELATED; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000023152};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 492..512
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 533..552
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 144..285
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 601 AA; 70169 MW; 8244021E66B5A399 CRC64;
MILVGIYIGD IFQLTDTLLI HSLLFLSYLW YQFKYLKYRN IAMVIIANIL YFIKICFNED
EEDTWKEILY SCLVFNCGIL SMIKSFYFTT KQQLRTMADD LSNHAQLRVE RKEHTRIMNS
LMPAPVTEQI LLKGDVPIYR RDVTIGFVYF TFYNKITMEK IKDNSPFVKV LHHLVINFDK
EIEQWEFDVV KIEHVGNAYL ICGGIMSSDT SFNHAEASYK LYFNSLTYIE KKFRRIVDKV
NAKLHVQSEL TMGIHTGPVI GTIIGTTRKF FRIFGDTVNT ASRVCTTGLE GCIQATQQTY
ESFDWLVRGD VPMKGKGNIC TYIVRGLNEK NENTSLSTSS WIKRHIRHKM TDNANLLEMN
FHQFLNSEDT HANPFTLRFP AKMHNQTDNN IFVKLSQLFV SSKLKSSVSL NDNSNHGRFS
NNQIKEFNLE EIYQVKLLTT NLCNYSRLQI ALWTFNLLLL LNSITIRKHM PHDNSVYNNS
SNMVTLPPMP HISSYMVILL SLETIVAFLI LLQTYVSHIL SHGRQERKLY YRRMIAVYIL
FWLHVLNVNY VSARTHRFFG RFIANIFYIM SFRVFPFRFF ELAISSIILA FFVDGLEPKG
F
//
