ID X6MV84_RETFI Unreviewed; 314 AA.
AC X6MV84;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Ubiquitin carboxyl-terminal hydrolase {ECO:0000313|EMBL:ETO17015.1};
GN ORFNames=RFI_20317 {ECO:0000313|EMBL:ETO17015.1};
OS Reticulomyxa filosa.
OC Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC Reticulomyxidae; Reticulomyxa.
OX NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO17015.1, ECO:0000313|Proteomes:UP000023152};
RN [1] {ECO:0000313|EMBL:ETO17015.1, ECO:0000313|Proteomes:UP000023152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24332546;
RA Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL Curr. Biol. 0:0-0(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO17015.1}.
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DR EMBL; ASPP01017450; ETO17015.1; -; Genomic_DNA.
DR AlphaFoldDB; X6MV84; -.
DR EnsemblProtists; ETO17015; ETO17015; RFI_20317.
DR OrthoDB; 1423057at2759; -.
DR Proteomes; UP000023152; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR PANTHER; PTHR21646; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR Pfam; PF00443; UCH; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00972; USP_1; 1.
DR PROSITE; PS50235; USP_3; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:ETO17015.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000023152};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 216..314
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 159..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 161..175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..199
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 314 AA; 36534 MW; 300BA522C80C315C CRC64;
MDEIFKAKQR KNSYILFSLQ CLTSFFNVKC NTSQIQLFCS IIKHFFLNLL FFSMLFAFLF
KRKQMEQEGY ARKPLQKWTL ADICRNKSLL KVLGLFCDCS DWNESLVEIG KKGMRQVIEM
KGTELTGQML ADFTVPKLQD EYKLGKLPSM KIVEALDKIK RNNPPSQTNE HRPSIQMITE
DTKNEEKEDG SEEHQSKSES KNVYTIEWIS EYQGLIGLKN LGSTCYLNSA VQCLLQVKPL
VHLFLFDHPY DYKYDYQYDS SKDWSMSIST AWSKTVYQAY TNQIKNGVYS LSALLSSLKK
VNHNFSEEKS KTFI
//
