ID X6N7R9_RETFI Unreviewed; 588 AA.
AC X6N7R9;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE SubName: Full=Initiation factor 2B related protein {ECO:0000313|EMBL:ETO22330.1};
GN ORFNames=RFI_14868 {ECO:0000313|EMBL:ETO22330.1};
OS Reticulomyxa filosa.
OC Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC Reticulomyxidae; Reticulomyxa.
OX NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO22330.1, ECO:0000313|Proteomes:UP000023152};
RN [1] {ECO:0000313|EMBL:ETO22330.1, ECO:0000313|Proteomes:UP000023152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24332546;
RA Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL Curr. Biol. 0:0-0(2013).
CC -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC {ECO:0000256|ARBA:ARBA00007251, ECO:0000256|RuleBase:RU003814}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO22330.1}.
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DR EMBL; ASPP01010825; ETO22330.1; -; Genomic_DNA.
DR AlphaFoldDB; X6N7R9; -.
DR EnsemblProtists; ETO22330; ETO22330; RFI_14868.
DR OrthoDB; 1406448at2759; -.
DR Proteomes; UP000023152; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR InterPro; IPR000649; IF-2B-related.
DR InterPro; IPR042529; IF_2B-like_C.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR43475; METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE; 1.
DR PANTHER; PTHR43475:SF3; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G14290); 1.
DR Pfam; PF01008; IF-2B; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|EMBL:ETO22330.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protein biosynthesis {ECO:0000313|EMBL:ETO22330.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000023152};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 71..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 588 AA; 68471 MW; EA050687E12D69CF CRC64;
MKDQSKIDQK NENNKILETL KKKQATFESF SSYSIFKLFI SITKFSCFIS CAMRNKDQHL
FRGNEKKIFK FGGPVCSTFM TAVSLSHIVI AFVVKEPSKI PNEILFLQQS AKMDECPKCW
CGIEVDVSEK ELSDNSYLEK VLISIIECTC LKRENLLISQ TGRPLRLYGE RKNVLLHPQL
FHLRSLHDTI CLNEKYMDYK WLTINEKIWS EMEWVPFTQN ALGTVLFDPV EQSQINWLKA
DRKHGASQLA IKCLEFLQEN YGTKKESMSP VHVYNYCYQL FKSRSSMQPV ANVVITFLEK
WNAREEDNTP QSVAKVCKSI IDEWSGDVDI RIPMMFHKLL CSRHENHKKL KLFTLSISSN
VYKALNFVSS EKHSHNKYTI DEIVIAESRP LFEGVSMAEK IENENVSVTI ITEAQMGIFI
PLCDAIVFGV DTIDLRNGYV INKVGKRYEN DREQGEAKMY FVFCYLLLHI FYLLWNLSVL
KNNVPVYVIG HESKLRRSNT DVTKEWPNLE EKRLLDQTKI NNEEKSTEDQ RNVELEEMDE
GEITKDWASN IKTKRKNCQI RNIYFEKIPL LLIDALVLTN QIIEQNKN
//
