ID X6NAT3_RETFI Unreviewed; 1460 AA.
AC X6NAT3;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=SET domain-containing protein {ECO:0000313|EMBL:ETO22417.1};
DE Flags: Fragment;
GN ORFNames=RFI_14781 {ECO:0000313|EMBL:ETO22417.1};
OS Reticulomyxa filosa.
OC Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC Reticulomyxidae; Reticulomyxa.
OX NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO22417.1, ECO:0000313|Proteomes:UP000023152};
RN [1] {ECO:0000313|EMBL:ETO22417.1, ECO:0000313|Proteomes:UP000023152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24332546;
RA Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL Curr. Biol. 0:0-0(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO22417.1}.
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DR EMBL; ASPP01010750; ETO22417.1; -; Genomic_DNA.
DR EnsemblProtists; ETO22417; ETO22417; RFI_14781.
DR OrthoDB; 52418at2759; -.
DR Proteomes; UP000023152; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd04371; DEP; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00610; DEP; 2.
DR SMART; SM00049; DEP; 2.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS50186; DEP; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000023152};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1172..1189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1201..1221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1250..1274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1286..1310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1331..1351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1357..1382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1403..1423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 300..382
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 550..610
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 746..781
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 852..887
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 231..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 490..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 670..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1085..1105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..94
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..290
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1460
FT /evidence="ECO:0000313|EMBL:ETO22417.1"
SQ SEQUENCE 1460 AA; 164294 MW; C9EA669A7D4A29BC CRC64;
MTQLTLSKDE ESHDLITSFS GPTVALDTRP YLAPSGSGGE EKREEEQDIG IGIEIGIGIG
IGDKRPLEPV TSVGTVNSAG SEEDDDDDGE GTDDSDNEFK YQEIRPDLWA VTAAATAAAN
AKKTMQKRAT AVGGLTIGIS QFREEGNVAS LEAKSSQSRN ENQLQSPKME IKRGSLAALQ
LYHQQKMSAS DIGKNGNDGK RASFDDSDIS LAVQRHRKTY SLQNLMKNRV VTVNSNRMEK
RAAKEKKKEK EKEKQNEKEQ EQEQEKEDDP TKPDRKGNSN NNKKKKGRQI PDYATMLQKM
SKEIEIKTRT YESQVMNDCF IGRDAITWMQ SKHYIRNRLA GVKLARHLQS LGYIQYVGGN
IRSNDESGNF EDKMDCFYQL HLHPPTTNTN TNANANANAN ANANANANTN SNAIVIAIPA
IDAKTTSPHA SGITRVASSP VIGMTKDLHA KNTNTLNVSI VVPSSARNSM LDDELPKIEQ
DGINLQLFQP TPLPSERSKK TTSRYFGQNG QRDSKDWPQV NAHICFLLKF LSIVQLKNIL
HNIANIWSKK DSTNGTAIVD WIEANVSGIK SRTGAIVLAQ QMVQNGMIKS IKSGKKKFVD
SNDDFYYFAE GVEDESLRFQ ELNANEKDIE SVIKTQPALN SANHSSRGSI TSNAITDSAI
GASVSAPPSV TGNGYISGDS KVKKNKHKRT RSSIADAING GANKNKNKDQ KEKNEAIKNL
LTHVIFAEVN NMNNDSMKAQ EEIVHQLLEE MRSHFVKCDK TQRGALDRKE FTEWLQKCGL
DLFADDVNTI FTMFDTHNNG LIDYRHFMQT NVPRSVPGIV KPTLPDLLKH AITMHFGTRD
KEDGVDNARE TRNIDAIIKA FHEINTKGTG FITLEELETA FAKHKIKMYE RSKTVFDLIA
KGKDKISFAD FNSVFSTAVY KNRTTAPTTR DILEQSQLLQ FQVCLHLYLF FKKKKKKMND
ISHEATPTRK EMTPMKKFVS FAPGSEKQES NAEYGDDETP AILENTTVHR KNESYSAGEC
EKKEDKHYIL QLFQLFSVGS VELIETKTYH ADQHENFEGE DETAMSPRIN FSNPAVLESR
KLPSPDTVAI PKQGSATQNE QDVNRREDTR NDLTMVESTK RTGDFHDHDN LDVQVPKVTS
DIVIEDESPQ VELVLSASEV WKRMYSPLIR EVWQMSWPAC LMLVPLHVIQ STGHNDLTVQ
IWIWYGFGVC LYLSLQSTMI GKRITTRIFW LSIGERDERE GNKAIDQTHI LCTLFIQIIG
IAVGLALLYT LLSLITLTQN SHNQEIFTII ACIFLWVIVA ISEAVGRMWF IQQVSKEQTK
RDYIQYALTR TLGVSIFWII QTLILLVVAA AKFAHEWAMF VYIIVVLSMI RGILVMLLSM
FVDHLSDHFY FEDGDRLDLK TRQIVATLLS LMTTYSCLHT LYLRSYTNAS STWPMYAGFV
TYQLLLFCGD YLLKNSEIRE
//
