ID X6NEL1_RETFI Unreviewed; 662 AA.
AC X6NEL1;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Protein kinase {ECO:0000313|EMBL:ETO24770.1};
GN ORFNames=RFI_12388 {ECO:0000313|EMBL:ETO24770.1};
OS Reticulomyxa filosa.
OC Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC Reticulomyxidae; Reticulomyxa.
OX NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO24770.1, ECO:0000313|Proteomes:UP000023152};
RN [1] {ECO:0000313|EMBL:ETO24770.1, ECO:0000313|Proteomes:UP000023152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24332546;
RA Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL Curr. Biol. 0:0-0(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO24770.1}.
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DR EMBL; ASPP01008973; ETO24770.1; -; Genomic_DNA.
DR AlphaFoldDB; X6NEL1; -.
DR EnsemblProtists; ETO24770; ETO24770; RFI_12388.
DR Proteomes; UP000023152; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR001293; Znf_TRAF.
DR PANTHER; PTHR22847:SF748; TRANSCRIPTIONAL REPRESSOR TUP11; 1.
DR PANTHER; PTHR22847; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF00400; WD40; 5.
DR Pfam; PF02176; zf-TRAF; 1.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 3.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:ETO24770.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000023152};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000313|EMBL:ETO24770.1};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 218..254
FT /note="TRAF-type"
FT /evidence="ECO:0000259|Pfam:PF02176"
FT REPEAT 411..458
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 497..519
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 520..564
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 565..616
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 298..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 270..297
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 300..314
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..362
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 662 AA; 75686 MW; 247ABF4CD2B4260E CRC64;
MITQLIFWCY FDKSSPAEKK KKIFILKKTH HINIVQLRLV WVQSQNPVIK NSVRHLKKIR
NQYKKSKDKM ADEQSKSQVK SEAASSNSCF AKDWILQTNQ AESVNHFTCL ICKQIVNNPI
EITCPQHEEM DECLIVGEDC LQHYLSESNN ACPISPHEDC QHSKSRSLQW QVSALSVMCP
REFKRNLQTS NGNGNGNGNE EEGQTKGKVI CNFNGKIKEL QNHLDNECPL RHSDCWFKSF
GCNFTCFGNQ LQEHLISDLR LHFDLVVQKV DLLQQVIQKT QNTVTQLQLE NQMLKSQMRV
DRTNRAEKPT DMSLKQSDDL PFQVLKQQEK SKKDIQKNDS NFKKMETEQK EKEKEKENDS
AKLQSDILQS IKVRKTFDGH KSGIISIDCC NSNDDYILCS GSGTAKHMQT LSGHSDHVYC
VKFSPYHFHH YYYSIICSAS LDKTIRFWDT NTGRTLQTIK KHKEGVCDIA FSPFNNGRYF
LISKKNAGMI GGAGYTICSG SWDMTIRLWD VETAKELIAF KGHENIVRSV KYSAIGGGAN
MICSGSEDYT IRLWDIRSKI QVQVFNGHTS TVTCAQYLPF KDRSASPFNG HNVICSTSWD
NSIRFWDIRA AKQLHMIEGN AMDCAILSLT FSPFNAKIMD NTDDCKFTFY CGSQTGIIRL
WG
//
