ID   X6NGH5_RETFI            Unreviewed;       322 AA.
AC   X6NGH5;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=SET domain-containing protein {ECO:0000259|PROSITE:PS50280};
DE   Flags: Fragment;
GN   ORFNames=RFI_12707 {ECO:0000313|EMBL:ETO24447.1};
OS   Reticulomyxa filosa.
OC   Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC   Reticulomyxidae; Reticulomyxa.
OX   NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO24447.1, ECO:0000313|Proteomes:UP000023152};
RN   [1] {ECO:0000313|EMBL:ETO24447.1, ECO:0000313|Proteomes:UP000023152}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24332546;
RA   Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA   Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA   Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT   "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL   Curr. Biol. 0:0-0(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETO24447.1}.
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DR   EMBL; ASPP01009217; ETO24447.1; -; Genomic_DNA.
DR   AlphaFoldDB; X6NGH5; -.
DR   EnsemblProtists; ETO24447; ETO24447; RFI_12707.
DR   OMA; RINSEEM; -.
DR   OrthoDB; 5304435at2759; -.
DR   Proteomes; UP000023152; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   PANTHER; PTHR46820; HISTONE-LYSINE N-METHYLTRANSFERASE SETD7; 1.
DR   PANTHER; PTHR46820:SF1; HISTONE-LYSINE N-METHYLTRANSFERASE SETD7; 1.
DR   Pfam; PF00856; SET; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000023152};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        221..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          157..307
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
FT   REGION          103..124
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        110..124
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ETO24447.1"
SQ   SEQUENCE   322 AA;  37648 MW;  E9BD25329CC50D27 CRC64;
     VNGIFEGKNQ YYMQDHSLLI KGQWKEGKMS GEISEYEIET LDVTARPIRS RLDVLPATHE
     RCQEQMDDWY KQHVFQMEKN LGANSDRLVG EWKKGSMVQA RFVSSDNDGD ANNAKEKKKK
     KSESEEKVAK EQWYCEDVSN EASIGGYPLL SDPYEVKCVY VAKSTLSDAN EGLFALRKLF
     KDEVVSFYNG LRVRHKTVDE RPWSENQYTN SVCSEFAVDS FVFFFSFLFF FGLFLSVGFV
     FDFEPQVPSE FAVMDKYCAT MGHKANHDWD KQNARYDTFY HPRFGDIKCL RAICDIEPNE
     EIFVDYDYSD EWPEWFVDKY SH
//