ID X6NKR1_RETFI Unreviewed; 374 AA.
AC X6NKR1;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE RecName: Full=Peptidase S53 activation domain-containing protein {ECO:0000259|SMART:SM00944};
GN ORFNames=RFI_11192 {ECO:0000313|EMBL:ETO25947.1};
OS Reticulomyxa filosa.
OC Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC Reticulomyxidae; Reticulomyxa.
OX NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO25947.1, ECO:0000313|Proteomes:UP000023152};
RN [1] {ECO:0000313|EMBL:ETO25947.1, ECO:0000313|Proteomes:UP000023152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24332546;
RA Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL Curr. Biol. 0:0-0(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO25947.1}.
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DR EMBL; ASPP01008183; ETO25947.1; -; Genomic_DNA.
DR AlphaFoldDB; X6NKR1; -.
DR EnsemblProtists; ETO25947; ETO25947; RFI_11192.
DR OrthoDB; 2326650at2759; -.
DR Proteomes; UP000023152; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR CDD; cd11377; Pro-peptidase_S53; 1.
DR InterPro; IPR015366; S53_propep.
DR PANTHER; PTHR14218; PROTEASE S8 TRIPEPTIDYL PEPTIDASE I CLN2; 1.
DR PANTHER; PTHR14218:SF15; TRIPEPTIDYL-PEPTIDASE 1; 1.
DR Pfam; PF09286; Pro-kuma_activ; 1.
DR SMART; SM00944; Pro-kuma_activ; 1.
DR SUPFAM; SSF54897; Protease propeptides/inhibitors; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000023152};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 63..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 248..373
FT /note="Peptidase S53 activation"
FT /evidence="ECO:0000259|SMART:SM00944"
SQ SEQUENCE 374 AA; 42942 MW; CCC8571ACF302E29 CRC64;
MEKREKRRNL KKTTKAMNAF ETGDCLADTE TTFLLHVGRN INERKKRNGW RAWVDSQFGH
YKCFVGAISS LVIVVIVAVV ILFGTEGVLS ETRIVSSSDE THSHALASSA LDKVGKWKSR
YVVEKPVDMN DMKNFEPLIE SQQCMIVPVH GATVGYKHVE YVYSPSTKQE EEEEEVYVAD
SSAKWHKENK GMIWKRNFED KETKKHATAT ATATSAKMTT MEESLIKKET SEKWVELEQM
SVKDVEKQLG WKLKQPLSLM ETVTLTFATK QQNSDLESVM AEVTKVSDPK SRSYGRYWTY
AQVHNHFKPS SVSIQTLVQY LTVFGILEEE IQWLTPNGDW LRVTMTVWQA NALLNTKFAY
WEQIKTGVEK KKFI
//
