ID X6NS34_RETFI Unreviewed; 333 AA.
AC X6NS34;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=RhoGAP domain containing protein {ECO:0000313|EMBL:ETO28748.1};
GN ORFNames=RFI_08377 {ECO:0000313|EMBL:ETO28748.1};
OS Reticulomyxa filosa.
OC Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC Reticulomyxidae; Reticulomyxa.
OX NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO28748.1, ECO:0000313|Proteomes:UP000023152};
RN [1] {ECO:0000313|EMBL:ETO28748.1, ECO:0000313|Proteomes:UP000023152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24332546;
RA Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL Curr. Biol. 0:0-0(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO28748.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ASPP01006491; ETO28748.1; -; Genomic_DNA.
DR AlphaFoldDB; X6NS34; -.
DR EnsemblProtists; ETO28748; ETO28748; RFI_08377.
DR OrthoDB; 48967at2759; -.
DR Proteomes; UP000023152; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR044785; RopGAP1-5.
DR PANTHER; PTHR23177; MKIAA1688 PROTEIN; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000023152}.
FT DOMAIN 117..301
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 63..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 333 AA; 38592 MW; 29B754CFFC29176B CRC64;
MAEVDDNSSF EATSEKQANT KVDDYIAQHN KLAESVRQFE ETRKKILKKK LREQTYFLIK
TKKKEKAEAS EQKEEKKEED TTKDNNTAQK DDNVDIDALS KSCLNKGIFF GKSYEECELI
HLPQYAVAIP AGLEGLKRRL LECEYITIIN NNNKNNNDKN EKRIEGNVLN NGSKISELQC
TPIEMAQVLK SWFREVLCDD PGFVTLKLLE ARTEAEVKDA FTELTEPRRS VLLWIFDLWI
EVEQRCNKNK MTLQSMSIVF SPNLVRTGDA SNPMIFLQYQ KEAQRVLEIA AHLRKSGQLQ
FDTAVLFLIP LFSFFLKPHL YKKKNLMYCS FCF
//
