ID X6P715_RETFI Unreviewed; 501 AA.
AC X6P715;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Ion transport domain-containing protein {ECO:0000259|Pfam:PF00520};
DE Flags: Fragment;
GN ORFNames=RFI_03692 {ECO:0000313|EMBL:ETO33417.1};
OS Reticulomyxa filosa.
OC Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC Reticulomyxidae; Reticulomyxa.
OX NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO33417.1, ECO:0000313|Proteomes:UP000023152};
RN [1] {ECO:0000313|EMBL:ETO33417.1, ECO:0000313|Proteomes:UP000023152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24332546;
RA Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL Curr. Biol. 0:0-0(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO33417.1}.
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DR EMBL; ASPP01003407; ETO33417.1; -; Genomic_DNA.
DR AlphaFoldDB; X6P715; -.
DR EnsemblProtists; ETO33417; ETO33417; RFI_03692.
DR Proteomes; UP000023152; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR002153; TRPC_channel.
DR PANTHER; PTHR10117; TRANSIENT RECEPTOR POTENTIAL CHANNEL; 1.
DR PANTHER; PTHR10117:SF54; TRANSIENT RECEPTOR POTENTIAL-GAMMA PROTEIN; 1.
DR Pfam; PF00520; Ion_trans; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000023152};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 33..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 479..500
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..238
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 392..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..421
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETO33417.1"
SQ SEQUENCE 501 AA; 56731 MW; D33C6B03271EC9CD CRC64;
KKKTKTKQGR YVTYEMLQLI LEGRNYLADV LNYWDICIVI VWTALAIMRF VLPWKGVLSP
KYWGISDNET AVDARNKPYT QVYMVLWGVQ CVLLWTRIAG ILQRIPSTGS LLKTVAKMIQ
DVANFFLILI VLTTGFVFAM YYIVSTDLSG NCAVNSSLGT FSSVLFYMAQ SLIGQQDWTT
ISSTNSENRP SMPPCFDQDR SRLAEGLLLL YAVLGTIMLL NLLIAMMATT FNSTTENAKI
EMNFSRIKNT FELSHKNAIM PPPFNMIVLV CMVVVILIDY GIRWCTGGWY VLCAKTFYPL
DYSLKQQLIR IRGLADEPNR TSSKVLGVAA NPNALGGGGG AGTSTNIRAL GSTNSPMLLR
FGSTNTSIID ESHSDDGKYA NPDEMKAFVQ DRDKPNADNN NNNNNNNNNN NNSINEVGSN
KHPSINLKWL NPLRRNMSRD ETMDSALIQM RRTEMQRRIR QNQKPFHQRI IQKLPKREWF
ENPFDFAAAV ISICFSFFFF F
//
