ID X6PB73_RETFI Unreviewed; 715 AA.
AC X6PB73;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=HECT domain-containing protein {ECO:0000259|PROSITE:PS50237};
GN ORFNames=RFI_01738 {ECO:0000313|EMBL:ETO35324.1};
OS Reticulomyxa filosa.
OC Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC Reticulomyxidae; Reticulomyxa.
OX NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO35324.1, ECO:0000313|Proteomes:UP000023152};
RN [1] {ECO:0000313|EMBL:ETO35324.1, ECO:0000313|Proteomes:UP000023152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24332546;
RA Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL Curr. Biol. 0:0-0(2013).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00104}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO35324.1}.
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DR EMBL; ASPP01001726; ETO35324.1; -; Genomic_DNA.
DR AlphaFoldDB; X6PB73; -.
DR EnsemblProtists; ETO35324; ETO35324; RFI_01738.
DR OrthoDB; 49176at2759; -.
DR Proteomes; UP000023152; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR InterPro; IPR043366; HECTD4.
DR PANTHER; PTHR46435; E3 UBIQUITIN-PROTEIN LIGASE HECTD4-RELATED; 1.
DR PANTHER; PTHR46435:SF1; E3 UBIQUITIN-PROTEIN LIGASE HECTD4-RELATED; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS50237; HECT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000023152};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT DOMAIN 608..703
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
FT REGION 99..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 715 AA; 80291 MW; 89EDDA7BF5686DCF CRC64;
MIIFPDLFSH DPDSSRPLTD KELKIEYEIF RNVYDESLHD IRVDILKTRK LVQKSDTQIY
IAAEQSTFDR VIEMSLLTLA VHQTLPVENP RHMLTSLASN SASTQPRSTD GNSNRPVRPS
SSSSNDLLSV EIARPPKVIK NEGYRLPPLF LGEVARAIQV SDSHYSVVSH LGPVVLTESD
ECVSGRSCPT GGVGEIHEFT VILWMYLEKK GSENTEMARN IFRKGDRNSN SLLPLICLTG
GTKKNTIQVQ VTTKGNNRIT LTHDGEDIKP RVWRHIAVTG NAIGVKLYVD GKLVQKQRTN
GPLKHNSDPI YLGKCPPGVD STYSTQPTVK SLGVNGSVLD CRYYLRCLQD KAIIRYKSET
QMLTKSSVPK IQFQSSRDPD SETKLSLQYF RDVAAYKVPE FDPGRWGSSL GTNLDNEVIT
MFEACYQQAA MHELREVWKL VAGSANVDAN GNPVDNGNER EVRNALRHLS QLNIVAHSLN
PDSKLLERHD ALSDIDLQTL KRRFFMLQML NHKMKTIFPL VDFTQVGLSW SLASRLCGLR
SLIFTDLKRQ PWQNVLQQTS SNHRTSVLVN RLKALRTRER ASTNALNAIE AAKKSVFGQV
YRILNFVKPV YLRCSANQRP WSIVYEGEGG TDAGGLFRDS LSAICADLQS DYLPLFVKCP
NSRGYGDNQE KWIPNPVCTS SLQLSMYTFV GKLMGTAIRG NTISTWTYRQ LCGNR
//
