ID   X6PC50_RETFI            Unreviewed;       568 AA.
AC   X6PC50;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=FH2 domain-containing protein {ECO:0000259|PROSITE:PS51444};
GN   ORFNames=RFI_01816 {ECO:0000313|EMBL:ETO35247.1};
OS   Reticulomyxa filosa.
OC   Eukaryota; Sar; Rhizaria; Retaria; Foraminifera; Monothalamids;
OC   Reticulomyxidae; Reticulomyxa.
OX   NCBI_TaxID=46433 {ECO:0000313|EMBL:ETO35247.1, ECO:0000313|Proteomes:UP000023152};
RN   [1] {ECO:0000313|EMBL:ETO35247.1, ECO:0000313|Proteomes:UP000023152}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24332546;
RA   Glockner G., Hulsmann N., Schleicher M., Noegel A.A., Eichinger L.,
RA   Gallinger C., Pawlowski J., Sierra R., Euteneuer U., Pillet L.,
RA   Moustafa A., Platzer M., Groth M., Szafranski K., Schliwa M.;
RT   "The Genome of the Foraminiferan Reticulomyxa filosa.";
RL   Curr. Biol. 0:0-0(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETO35247.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ASPP01001815; ETO35247.1; -; Genomic_DNA.
DR   AlphaFoldDB; X6PC50; -.
DR   EnsemblProtists; ETO35247; ETO35247; RFI_01816.
DR   OMA; HFLNYFE; -.
DR   OrthoDB; 8473at2759; -.
DR   Proteomes; UP000023152; Unassembled WGS sequence.
DR   GO; GO:0071203; C:WASH complex; IEA:InterPro.
DR   Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR   InterPro; IPR015425; FH2_Formin.
DR   InterPro; IPR042201; FH2_Formin_sf.
DR   InterPro; IPR019309; WASHC3.
DR   PANTHER; PTHR45725:SF1; DELPHILIN; 1.
DR   PANTHER; PTHR45725; FORMIN HOMOLOGY 2 FAMILY MEMBER; 1.
DR   Pfam; PF10152; CCDC53; 2.
DR   Pfam; PF02181; FH2; 1.
DR   SMART; SM00498; FH2; 1.
DR   SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR   PROSITE; PS51444; FH2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000023152}.
FT   DOMAIN          296..568
FT                   /note="FH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51444"
FT   REGION          1..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          269..297
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          68..102
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        20..42
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        270..292
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   568 AA;  62404 MW;  6CAF35DB5A307A85 CRC64;
     MLDRGEESAT DKAAKQGFLS AKHSNLSRAS TTSNLVTTKG SDDAVYPSYQ ELKHLLNVRE
     VDLQQVKKSK ESQRIEQLET SKLELEKDLE KLQAQMVQLQ KGGVVSTTAA TNTQASAASA
     IANSLPQNNA TATATTTSGG GDDAYAKYRK MLKMGMPKQS VINKMIQDKV DKSAIDTLES
     TGELPGGGAA SGASTAAPSN PVAALIAGNA NATASTTTAT ATATLTPEEE AKLAPYRKMQ
     KINMPQQSII NKMIQDGIDK ALIDKMFGGG KDASKGETKA DAKKKEEPQL PPGLKPKKVI
     QPNVKMRNLH WTPLNPFDVD KTIWKDINDE AVKLDASDLE SNFCWKEIER KTPEKTPTSS
     PEEAEKVTVL DSKRGYNVEI FLGRLKMDNW AIRDAMLKMD ENVLQIDAIN KLINFVPTPE
     EADLISQYED TPNLAAPETY FKIIKSVDSN LKQRLELWSF KIQFSEEVKS EQEKIEAVNR
     GVQSLRKSTN FKKMLTYVLA VGNYMNGGTK NGAAFGFKLN SLTQLSRSRT VDNKQTLLQY
     LYVQLEQKDT KVLEFSNDLA SLDDATTG
//