ID X7E8X5_9GAMM Unreviewed; 322 AA.
AC X7E8X5;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=3-hydroxybutyryl-CoA dehydrogenase {ECO:0000313|EMBL:ETX12524.1};
DE EC=1.1.1.157 {ECO:0000313|EMBL:ETX12524.1};
GN ORFNames=MUS1_02735 {ECO:0000313|EMBL:ETX12524.1};
OS Marinomonas ushuaiensis DSM 15871.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Marinomonas.
OX NCBI_TaxID=1122207 {ECO:0000313|EMBL:ETX12524.1, ECO:0000313|Proteomes:UP000054058};
RN [1] {ECO:0000313|EMBL:ETX12524.1, ECO:0000313|Proteomes:UP000054058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15871 {ECO:0000313|EMBL:ETX12524.1,
RC ECO:0000313|Proteomes:UP000054058};
RA Lai Q., Shao Z.S.;
RT "Marinomonas ushuaiensis DSM 15871 Genome Sequencing.";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETX12524.1}.
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DR EMBL; JAMB01000001; ETX12524.1; -; Genomic_DNA.
DR RefSeq; WP_036158692.1; NZ_JAMB01000001.1.
DR AlphaFoldDB; X7E8X5; -.
DR STRING; 1122207.MUS1_02735; -.
DR PATRIC; fig|1122207.3.peg.562; -.
DR eggNOG; COG1250; Bacteria.
DR OrthoDB; 9803287at2; -.
DR Proteomes; UP000054058; Unassembled WGS sequence.
DR GO; GO:0008691; F:3-hydroxybutyryl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR InterPro; IPR006108; 3HC_DH_C.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR48075:SF1; LAMBDA-CRYSTALLIN HOMOLOG; 1.
DR Pfam; PF00725; 3HCDH; 1.
DR Pfam; PF02737; 3HCDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:ETX12524.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054058}.
FT DOMAIN 11..185
FT /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF02737"
FT DOMAIN 191..273
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
SQ SEQUENCE 322 AA; 36195 MW; 381E2D16B1306805 CRC64;
MARPNPNEVT HVGVIGTGVI GGGWALHFLR MGMNVVAYDP GPNAKEKLLA MVDHVWPTIE
KLGLREGASR DNLRFVDSLE DMVSCVQVIQ ENTPERLDAK RDLFAELDRI TPSDVVIISS
TSGLPMTDMA SDLKNQPNRF VVGHPFNPPY LMPFCEVCGG ERTSQDVVDW TAEFYEAIEK
QVAKMEKELP GFIGNRLQEA IWREALHMVK NKECTVEDID KAIIHGPGLR WAIMGHCLTY
HLGGGQGGMA YLLDHFEHSL EEPWTRLKAP EVTQELKDDM VQGCLNQANG ASINELIQER
DDCLIRIMQT LDEYRQEKGI KR
//
