ID X7EHT1_9RHOB Unreviewed; 647 AA.
AC X7EHT1;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:ETX15462.1};
GN ORFNames=OCH239_16730 {ECO:0000313|EMBL:ETX15462.1};
OS Roseivivax halodurans JCM 10272.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseivivax.
OX NCBI_TaxID=1449350 {ECO:0000313|EMBL:ETX15462.1, ECO:0000313|Proteomes:UP000022447};
RN [1] {ECO:0000313|EMBL:ETX15462.1, ECO:0000313|Proteomes:UP000022447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 10272 {ECO:0000313|EMBL:ETX15462.1,
RC ECO:0000313|Proteomes:UP000022447};
RA Lai Q., Li G., Shao Z.;
RT "Roseivivax halodurans JCM 10272 Genome Sequencing.";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETX15462.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JALZ01000005; ETX15462.1; -; Genomic_DNA.
DR RefSeq; WP_037260323.1; NZ_JALZ01000005.1.
DR AlphaFoldDB; X7EHT1; -.
DR STRING; 1449350.OCH239_16730; -.
DR PATRIC; fig|1449350.3.peg.1467; -.
DR eggNOG; COG0768; Bacteria.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000022447; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000022447};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 62..236
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 269..602
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 647 AA; 71245 MW; 55BEF04703267E04 CRC64;
MRRTPKDNTD SARRITRRGL MLGGMQLGFA TVLGMRMRYM QIDQGEEFRL LAEENRINVR
LIPPARGQIF DRKGVVIAAN TPAYRITVVR EDAGDLDDTL ARLAELVDLD PGEVERAVAE
MRRSAPFLPI AVADQVSWEA VSRVAANAPA LPGVNPEVGL SRHYPHGEIF AHVVGYVQPV
SESDLARYED PDPVLRIPRF QFGKIGVETK YEDILRGRAG SKRVEVNAAG RIMRELDRRE
GEAGADLQLS VDSDLQDYIH ARLGDESASV VVMDLEHGDL KAMVSAPGYD PNKFVRGISY
DDYGALQADE RAPLVSKTVQ GFYPPGSCFK MVTALAALEA GVTGPGNTVW CPGHLKVGSR
RFHCWKRAGH GHMNVEDALM QSCDVYFYEI ALRVGIDQIA EMGRKLGLGM AHDVPMSAVG
EGIMPDKAWK RERWGQEWRI GDTVNCSIGQ GDVLTSPLQL AVMAARLATG RTISPRLVKS
IDGVEEPSRG GEPLDIDPTH LRWMQKAMFD VSNSTRGTAY RSRIEAEEMR MAGKTGTSQV
RNITAAERAR GVTRNEDLPW KRRDHGLFVN FAPYDNPRIA VATIVEHGGG GSSAAAPIAR
DVTLQALYEG DPPLEAYPSA DRGQIEELQK RLRERRSMPL ASGTSRA
//
