ID X8CE13_MYCIT Unreviewed; 579 AA.
AC X8CE13;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=Beta-ketoacyl synthase, C-terminal domain protein {ECO:0000313|EMBL:EUA54304.1};
GN ORFNames=I550_5945 {ECO:0000313|EMBL:EUA54304.1};
OS Mycobacterium intracellulare 1956.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium avium complex (MAC).
OX NCBI_TaxID=1299331 {ECO:0000313|EMBL:EUA54304.1, ECO:0000313|Proteomes:UP000020825};
RN [1] {ECO:0000313|EMBL:EUA54304.1, ECO:0000313|Proteomes:UP000020825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1956 {ECO:0000313|EMBL:EUA54304.1,
RC ECO:0000313|Proteomes:UP000020825};
RA Zelazny A., Olivier K., Holland S., Lenaerts A., Ordway D., DeGroote M.A.,
RA Parker T., Sizemore C., Tallon L.J., Sadzewicz L.K., Sengamalay N.,
RA Fraser C.M., Hine E., Shefchek K.A., Das S.P., Tettelin H.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EUA54304.1}.
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DR EMBL; JAOG01000003; EUA54304.1; -; Genomic_DNA.
DR AlphaFoldDB; X8CE13; -.
DR PATRIC; fig|1299331.3.peg.5811; -.
DR Proteomes; UP000020825; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 21..98
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 119..544
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 552..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 579 AA; 61806 MW; 4C9341CA919EDFBB CRC64;
MADTEHPEST DHPPAAKGTD MTVPEMRQWL RNWVGKAVGR SPDDIDESVP MVELGLSSRD
AVAMAADIED MTGVTLSVAV AFQHPTIESL ATRIVEGEPE IDTAADDAMD WTRTGPAERV
DIAIVGLSTR LPGDMNSPDE TWQALMEGRD AITDLPEGRW SEFLDEPRIA ARVGAARTRG
GYLKDIKGFD SEFFAVAKTE ADNIDPQQRM ALELTWEALE HARIPASSLR GEAVGVYVGF
SNNDYQFLAV SDPTVAHPYA ITGTASSIIA NRVSYFYDFR GPSVALDTAC SSSLVATHQA
VQALRNGECD VAVAGGVNAL LTPLVTLGFD EIGQVLSPDG RIKSFSSDAD GYTRSEGGGM
FVLKRVDDAR RDGDQILAVI AGSAVNHDGR SNGLIAPNQD AQAEVLRRAY KDAGIDPRTV
DYIEAHGTGT VLGDPIEAEA LGRIVGRGRP ADRPALLGAV KTNVGHLESA AGAASLAKVV
LALQHDKLPP SINFAGPSPY IDFDGMRLKV VDSATDWPRY GGYALAGCPA LASAGPTRTW
WCARSCRATW WSASPSPPPS RGRRSRRGPH ARGPLAAVR
//
