ID X8CED4_MYCIT Unreviewed; 387 AA.
AC X8CED4;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=Uroporphyrinogen-III synthase HemD family protein {ECO:0000313|EMBL:EUA53655.1};
GN ORFNames=I550_5293 {ECO:0000313|EMBL:EUA53655.1};
OS Mycobacterium intracellulare 1956.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium avium complex (MAC).
OX NCBI_TaxID=1299331 {ECO:0000313|EMBL:EUA53655.1, ECO:0000313|Proteomes:UP000020825};
RN [1] {ECO:0000313|EMBL:EUA53655.1, ECO:0000313|Proteomes:UP000020825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1956 {ECO:0000313|EMBL:EUA53655.1,
RC ECO:0000313|Proteomes:UP000020825};
RA Zelazny A., Olivier K., Holland S., Lenaerts A., Ordway D., DeGroote M.A.,
RA Parker T., Sizemore C., Tallon L.J., Sadzewicz L.K., Sengamalay N.,
RA Fraser C.M., Hine E., Shefchek K.A., Das S.P., Tettelin H.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EUA53655.1}.
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DR EMBL; JAOG01000003; EUA53655.1; -; Genomic_DNA.
DR AlphaFoldDB; X8CED4; -.
DR PATRIC; fig|1299331.3.peg.5170; -.
DR Proteomes; UP000020825; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006780; P:uroporphyrinogen III biosynthetic process; IEA:InterPro.
DR CDD; cd06578; HemD; 1.
DR CDD; cd00383; trans_reg_C; 1.
DR Gene3D; 3.40.50.10090; -; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR039793; UROS/Hem4.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR40082; BLR5956 PROTEIN; 1.
DR PANTHER; PTHR40082:SF1; BLR5956 PROTEIN; 1.
DR Pfam; PF02602; HEM4; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF69618; HemD-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU01091}.
FT DOMAIN 285..378
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 285..378
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 387 AA; 41365 MW; 36A82F9B8A52AE1B CRC64;
MAPQLAPPDS APLTGYRIAV TSANRAEELC ALLRRNGAEV SSAAAINLIA LPEDEELHRH
TEAVIAEPPD ILVAHTGIGF RGWVAAADGW GLATQLLASL SRARIVARGP KATGALRAAG
LHEEWSPRSE SSSEVLRYLL ESDIAGKRVA VQLHGAADTW DPFPEFLNGL RSAGAQVVPI
HVYRWKPTPA GGDFDQLVTS VARRQFDAVT FTSAPAGAAL LERSRELGVE EQLLQALRSD
VHAMCVGPVT AQPLLRAGVP TSSPERMRLG ALARHIAQEL PTLRSTTIRA AGHEMEIRGT
CVLVDGSPRS LSGSGMATLR ALAERPGDVV ARNDLLRVLP GNSNDPHAVD TAVLRLRTAL
GDKNIIATVV KRGYRLAIDH PDESPWH
//
