ID X8CLJ8_MYCIT Unreviewed; 597 AA.
AC X8CLJ8;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Diguanylate cyclase domain protein {ECO:0000313|EMBL:EUA56130.1};
GN ORFNames=I550_4288 {ECO:0000313|EMBL:EUA56130.1};
OS Mycobacterium intracellulare 1956.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium avium complex (MAC).
OX NCBI_TaxID=1299331 {ECO:0000313|EMBL:EUA56130.1, ECO:0000313|Proteomes:UP000020825};
RN [1] {ECO:0000313|EMBL:EUA56130.1, ECO:0000313|Proteomes:UP000020825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1956 {ECO:0000313|EMBL:EUA56130.1,
RC ECO:0000313|Proteomes:UP000020825};
RA Zelazny A., Olivier K., Holland S., Lenaerts A., Ordway D., DeGroote M.A.,
RA Parker T., Sizemore C., Tallon L.J., Sadzewicz L.K., Sengamalay N.,
RA Fraser C.M., Hine E., Shefchek K.A., Das S.P., Tettelin H.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EUA56130.1}.
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DR EMBL; JAOG01000002; EUA56130.1; -; Genomic_DNA.
DR AlphaFoldDB; X8CLJ8; -.
DR PATRIC; fig|1299331.3.peg.4186; -.
DR Proteomes; UP000020825; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR46663; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR PANTHER; PTHR46663:SF4; TWO-COMPONENT RESPONSE REGULATOR; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08447; PAS_3; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 383..435
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 467..597
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 597 AA; 64685 MW; 1288E5F5B14B8EFA CRC64;
MLRAERRERE GQPMDRPGPD ARLESAMNTS GRAAALLVLV VAALTWVGWT AGIERLTRIY
PTWPQMMPWT ALWLAALGAA ILLQWGSPSR ERRWAGRCLA AAAAAFAVLV LAEYASLGSF
TVDRIWFGEA VGMREWSWPG RPSVQTALSA LPLATAVALI RVDRCTRAVW PLCLAASAAI
PFVTAGAYLF DALALVGVSP SKGQAFLTAA ALLLLVAATS LARVDRFPLA WLLARPDRSS
LVRLLAILAG FPLVVAVVRP IFLELGPDAN AQWTFSILLG TAVVGAVTFY FSQREQHLLI
AKELASKQRA EAETRYRILA DNAVDIIVHF RGGGVAWISP SVEPALGGPL SRWTGTDFAR
RIHPEDRDKL QTALRRIAGG EQVLQRFRVC SLDGEYHWVD GHGKPYTDAQ GNTDGLIAAL
RVVDDQVEAE QQLERLARFD TLTGLVNRAE ALARLDAALR QPRPPETHVG VLFCDVDHFK
AINDRWGHGT GDVVLATVAA RIRASVRRED TVGRTGGDEM LILLPGVRSA DELAQIAEKI
RRRVAEPIHV SGNTIGATLS IGATLALPAE SVDAVTARAD EAMYRAKSGD RNAVVAT
//
