ID   X8CN86_MYCIT            Unreviewed;       433 AA.
AC   X8CN86;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=PIN domain protein {ECO:0000313|EMBL:EUA57832.1};
GN   ORFNames=I550_0964 {ECO:0000313|EMBL:EUA57832.1};
OS   Mycobacterium intracellulare 1956.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=1299331 {ECO:0000313|EMBL:EUA57832.1, ECO:0000313|Proteomes:UP000020825};
RN   [1] {ECO:0000313|EMBL:EUA57832.1, ECO:0000313|Proteomes:UP000020825}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1956 {ECO:0000313|EMBL:EUA57832.1,
RC   ECO:0000313|Proteomes:UP000020825};
RA   Zelazny A., Olivier K., Holland S., Lenaerts A., Ordway D., DeGroote M.A.,
RA   Parker T., Sizemore C., Tallon L.J., Sadzewicz L.K., Sengamalay N.,
RA   Fraser C.M., Hine E., Shefchek K.A., Das S.P., Tettelin H.;
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SIMILARITY: Belongs to the PINc/VapC protein family.
CC       {ECO:0000256|ARBA:ARBA00038093}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EUA57832.1}.
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DR   EMBL; JAOG01000001; EUA57832.1; -; Genomic_DNA.
DR   AlphaFoldDB; X8CN86; -.
DR   PATRIC; fig|1299331.3.peg.938; -.
DR   Proteomes; UP000020825; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   CDD; cd09883; PIN_VapC_PhoHL-ATPase; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003714; PhoH.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR002716; PIN_dom.
DR   PANTHER; PTHR30473:SF2; PIN DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR30473; PROTEIN PHOH; 1.
DR   Pfam; PF02562; PhoH; 1.
DR   Pfam; PF13638; PIN_4; 1.
DR   SMART; SM00670; PINc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Toxin-antitoxin system {ECO:0000256|ARBA:ARBA00022649}.
FT   DOMAIN          5..132
FT                   /note="PIN"
FT                   /evidence="ECO:0000259|SMART:SM00670"
SQ   SEQUENCE   433 AA;  46995 MW;  0F3C1045D7754B06 CRC64;
     MTDIRTYVID TSVLLSDPWA CSRFAEHEVV VPLVVISELE AKRHHHELGW FARQALRLFD
     DLRLVHGRLD QPIPVGTQGG TLHVELNHTD PAVLPAGFRN DNNDCRILSC AANLAAEGKR
     VTLVSKDIPL RVKAAAVGLA ADEYHAQDVV ASGWSGMREI ETATEDIDAL FSDGEIDLAE
     ARDLPCHTGI RLLGGSSHAL GRVNADKRVQ LVRGDREVFG LRGRSAEQRV ALDLLLDESV
     GIVSLGGKAG TGKSALALCA GLEAVLERRT QRKVVVFRPL YAVGGQELGY LPGSESEKMG
     PWAQAVFDTL EGLASPAVLE EVLSRGMLEV LPLTHIRGRS LHDSFVIVDE AQSLERNVLL
     TVLSRLGTGS RVVLTHDIAQ RDNLRVGRHD GVAAVIEKLK GHPLFAHITL LRSERSPIAA
     LVTEMLEEIA GPH
//