ID Y1586_HAEIN Reviewed; 519 AA.
AC P44263;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE RecName: Full=Uncharacterized protein HI_1586;
GN OrderedLocusNames=HI_1586;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; L42023; AAC23234.1; -; Genomic_DNA.
DR PIR; C64037; C64037.
DR RefSeq; NP_439731.1; NC_000907.1.
DR AlphaFoldDB; P44263; -.
DR STRING; 71421.HI_1586; -.
DR EnsemblBacteria; AAC23234; AAC23234; HI_1586.
DR KEGG; hin:HI_1586; -.
DR PATRIC; fig|71421.8.peg.1660; -.
DR eggNOG; COG1757; Bacteria.
DR HOGENOM; CLU_018751_1_0_6; -.
DR OrthoDB; 9762978at2; -.
DR PhylomeDB; P44263; -.
DR BioCyc; HINF71421:G1GJ1-1602-MONOMER; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR PANTHER; PTHR43478; NA+/H+ ANTIPORTER-RELATED; 1.
DR PANTHER; PTHR43478:SF1; NA_H_ANTIPORTER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03553; Na_H_antiporter; 1.
PE 4: Predicted;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..519
FT /note="Uncharacterized protein HI_1586"
FT /id="PRO_0000078093"
FT TRANSMEM 19..39
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 179..199
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 220..240
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 270..290
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 311..331
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 345..365
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 386..406
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 413..433
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 475..495
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 496..516
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 519 AA; 55499 MW; 0EBF908C0454E4B1 CRC64;
MLSVLSINYR YYLMELIDFS SSVWSIVPAL LAIILAIATR RVLVSLSAGI IIGSLMLSDW
QIGSAFNYLV KNVVSLVYAD GEINSNMNIV LFLLLLGVLT ALLTVSGSNR AFAEWAQSRI
KGRRGAKLLA ASLVFVTFID DYFHSLAVGA IARPVTDRFK VSRAKLAYIL DSTAAPMCVM
MPVSSWGAYI ITLIGGLLAT YSITEYTPIG AFVAMSSMNF YAIFSIIMVF FVAYFSFDIA
SMVRHEKLAL KNTEDQLEEE TGTKGQVRNL ILPILVLIIA TVSMMIYTGA EALAADGKVF
SVLGTFENTV VGTSLVVGGF CSIIISTLLI ILDRQVSVPE YVRSWIVGIK SMSGAIAILF
FAWTINKIVG DMQTGKYLSS LVSGNIPMQF LPVILFVLGA AMAFSTGTSW GTFGIMLPIA
AAMAANAAPE LLLPCLSAVM AGAVCGDHCS PVSDTTILSS TGAKCNHIDH VTTQLPYAAT
VATATSIGYI VVGFTYSGLA GFAATAVSLI VIIFAVKKR
//
