ID Y160_AERHH Reviewed; 224 AA.
AC A0KEM8;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 12-DEC-2006, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE RecName: Full=UPF0758 protein AHA_0160;
GN OrderedLocusNames=AHA_0160;
OS Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC
OS 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=380703;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC
RC 2358 / NCIMB 9240 / NCTC 8049;
RX PubMed=16980456; DOI=10.1128/jb.00621-06;
RA Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.H.,
RA Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S.,
RA Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades.";
RL J. Bacteriol. 188:8272-8282(2006).
CC -!- SIMILARITY: Belongs to the UPF0758 family. {ECO:0000305}.
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DR EMBL; CP000462; ABK37930.1; -; Genomic_DNA.
DR RefSeq; WP_011704181.1; NC_008570.1.
DR RefSeq; YP_854693.1; NC_008570.1.
DR AlphaFoldDB; A0KEM8; -.
DR SMR; A0KEM8; -.
DR STRING; 380703.AHA_0160; -.
DR EnsemblBacteria; ABK37930; ABK37930; AHA_0160.
DR GeneID; 77272127; -.
DR KEGG; aha:AHA_0160; -.
DR PATRIC; fig|380703.7.peg.150; -.
DR eggNOG; COG2003; Bacteria.
DR HOGENOM; CLU_073529_0_1_6; -.
DR OrthoDB; 9804482at2; -.
DR Proteomes; UP000000756; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd08071; MPN_DUF2466; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR InterPro; IPR037518; MPN.
DR InterPro; IPR025657; RadC_JAB.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR001405; UPF0758.
DR InterPro; IPR020891; UPF0758_CS.
DR InterPro; IPR046778; UPF0758_N.
DR NCBIfam; TIGR00608; radc; 1.
DR PANTHER; PTHR30471; DNA REPAIR PROTEIN RADC; 1.
DR PANTHER; PTHR30471:SF3; UPF0758 PROTEIN YEES-RELATED; 1.
DR Pfam; PF04002; RadC; 1.
DR Pfam; PF20582; UPF0758_N; 1.
DR SUPFAM; SSF102712; JAB1/MPN domain; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
DR PROSITE; PS50249; MPN; 1.
DR PROSITE; PS01302; UPF0758; 1.
PE 3: Inferred from homology;
KW Hydrolase; Metal-binding; Metalloprotease; Protease; Reference proteome;
KW Zinc.
FT CHAIN 1..224
FT /note="UPF0758 protein AHA_0160"
FT /id="PRO_1000001641"
FT DOMAIN 102..224
FT /note="MPN"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT MOTIF 173..186
FT /note="JAMM motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 173
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 175
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 186
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
SQ SEQUENCE 224 AA; 24855 MW; BB76C11E74F309C6 CRC64;
MSIKEWPEDE RPREKLLRQG PGGLSDAELL AIFLRTGVSG LSAVDLSRHL LQQFGSLRAL
LGAEQRAFCA AHGLGPAKYA QLQAVLEMGK RHLAEQLQRG DPLTSPQLTR DYLQAQLRDR
PREVFALLLL DNQHRVIQFV ELFYGTLDSA SVWPREIVQI ALKHNAAAVI LAHNHPSGVA
EPSRADRQIT DRITAALALI DIRVLDHLVI GDGITVSFAE RGWL
//
