ID Y2530_DICDI Reviewed; 301 AA.
AC Q559I8;
DT 23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=Uncharacterized protein DDB_G0272530;
DE Flags: Precursor;
GN ORFNames=DDB_G0272530;
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=12097910; DOI=10.1038/nature00847;
RA Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [3]
RP DEVELOPMENTAL STAGE [LARGE SCALE ANALYSIS].
RX PubMed=12796308; DOI=10.1128/ec.2.3.627-637.2003;
RA Maeda M., Sakamoto H., Iranfar N., Fuller D., Maruo T., Ogihara S.,
RA Morio T., Urushihara H., Tanaka Y., Loomis W.F.;
RT "Changing patterns of gene expression in Dictyostelium prestalk cell
RT subtypes recognized by in situ hybridization with genes from microarray
RT analyses.";
RL Eukaryot. Cell 2:627-637(2003).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- DEVELOPMENTAL STAGE: Expressed in pstO cells (and not in pstA cells)
CC throughout development. {ECO:0000269|PubMed:12796308}.
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DR EMBL; AAFI02000008; EAL71189.1; -; Genomic_DNA.
DR RefSeq; XP_645118.1; XM_640026.1.
DR AlphaFoldDB; Q559I8; -.
DR SMR; Q559I8; -.
DR PaxDb; 44689-DDB0229929; -.
DR EnsemblProtists; EAL71189; EAL71189; DDB_G0272530.
DR GeneID; 8618513; -.
DR KEGG; ddi:DDB_G0272530; -.
DR dictyBase; DDB_G0272530; -.
DR eggNOG; ENOG502R98R; Eukaryota.
DR HOGENOM; CLU_925680_0_0_1; -.
DR InParanoid; Q559I8; -.
DR PhylomeDB; Q559I8; -.
DR PRO; PR:Q559I8; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0039706; F:co-receptor binding; IBA:GO_Central.
DR GO; GO:0048019; F:receptor antagonist activity; IBA:GO_Central.
DR GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IBA:GO_Central.
DR InterPro; IPR006796; Dickkopf_N.
DR PANTHER; PTHR33459:SF1; -; 1.
DR PANTHER; PTHR33459; DD-GDCA PROTEIN; 1.
DR Pfam; PF04706; Dickkopf_N; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Reference proteome; Secreted; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..301
FT /note="Uncharacterized protein DDB_G0272530"
FT /id="PRO_0000392618"
FT CARBOHYD 19
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 59
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 102
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 180
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 301 AA; 32706 MW; F5A0ED556FA82D21 CRC64;
MKIKLILVLI VFLTIVNVNN SIDLCLSNPK KALVNQACKY STDCEYPLFC GSGNGYGKNA
TCSKNIETGG SCESNNQCTP CNVCFNAKCK VKLYLGDACD ENKSYCSSSV CIKGKCSIQG
DVCTANNQCK FNNYCKSGKC VPLEKEGSSC DKDSSCSLTN ACVGGKCVTK YQKPLGAVCN
SSNECQVFSG HVCGANGKCS VYNQLLSKCK ENSDCGPNGM CMCKSETENV CVDLSVGALK
NDKCPSLLSS FSSCMTRERC TENTPTGCPK CYPIFMCYQY SCFYMNQFIR STQNYYKSFC
S
//
