ID Y788_ARCFU Reviewed; 308 AA.
AC O29470;
DT 15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 27-MAR-2024, entry version 116.
DE RecName: Full=Uncharacterized transporter AF_0788;
GN OrderedLocusNames=AF_0788;
OS Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS 100126 / VC-16).
OC Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC Archaeoglobus.
OX NCBI_TaxID=224325;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX PubMed=9389475; DOI=10.1038/37052;
RA Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA Smith H.O., Woese C.R., Venter J.C.;
RT "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT archaeon Archaeoglobus fulgidus.";
RL Nature 390:364-370(1997).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the EamA transporter family. {ECO:0000305}.
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DR EMBL; AE000782; AAB90451.1; -; Genomic_DNA.
DR PIR; D69348; D69348.
DR AlphaFoldDB; O29470; -.
DR SMR; O29470; -.
DR STRING; 224325.AF_0788; -.
DR PaxDb; 224325-AF_0788; -.
DR EnsemblBacteria; AAB90451; AAB90451; AF_0788.
DR KEGG; afu:AF_0788; -.
DR eggNOG; arCOG00271; Archaea.
DR HOGENOM; CLU_033863_21_3_2; -.
DR OrthoDB; 17861at2157; -.
DR PhylomeDB; O29470; -.
DR Proteomes; UP000002199; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR000620; EamA_dom.
DR PANTHER; PTHR42920:SF5; EAMA DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42920; OS03G0707200 PROTEIN-RELATED; 1.
DR Pfam; PF00892; EamA; 2.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..308
FT /note="Uncharacterized transporter AF_0788"
FT /id="PRO_0000108203"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 201..221
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 226..246
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 263..283
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 285..305
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 52..166
FT /note="EamA 1"
FT DOMAIN 178..306
FT /note="EamA 2"
SQ SEQUENCE 308 AA; 34282 MW; BCD0ED6AEA920D88 CRC64;
MGEDRRSLRV DYDDNFLRNN ICSLKVSFIK QQGGAEGVKR LYADLGLALV ALIWGSTFPV
VKIALDSMSP FAFNTVRFFI ACLFFLPFLK GWDFKDGFKI GIASFLGYTF QTVGLDYTTA
TNAGFITSTY VVLAPIISWL VYKDVFDKRD VSGVLLAFVG FYFLSGYSGF NIGDILMLFC
ALFFGAEIAM ISHYSRLSNP TMLAFWQSFA IFILSAPFAV FTTTKFEINT TVILCLLITA
FFATFVAKML QNWLQSYTKS SDAAVILSLE GVFAHLFSVA VLAEILTPVQ YFGAFLILLA
VIIVSLRV
//
