ID YIPF2_RAT Reviewed; 311 AA.
AC Q5XIT3;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 24-JAN-2024, entry version 102.
DE RecName: Full=Protein YIPF2;
DE AltName: Full=YIP1 family member 2;
GN Name=Yipf2;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBUNIT: Interacts with YIPF6; this interaction may stabilize YIPF2.
CC May also form a ternary complex with YIPF1 and YIPF6.
CC {ECO:0000250|UniProtKB:Q9BWQ6}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network membrane
CC {ECO:0000250|UniProtKB:Q9BWQ6}; Multi-pass membrane protein
CC {ECO:0000250|UniProtKB:Q9BWQ6}. Golgi apparatus, trans-Golgi network
CC membrane {ECO:0000250|UniProtKB:Q9BWQ6}. Late endosome membrane
CC {ECO:0000250|UniProtKB:Q9BWQ6}. Note=Mainly localizes within
CC medial-/trans-Golgi and trans-Golgi network (TGN), while less so within
CC cis-Golgi. {ECO:0000250|UniProtKB:Q9BWQ6}.
CC -!- SIMILARITY: Belongs to the YIP1 family. {ECO:0000305}.
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DR EMBL; BC083587; AAH83587.1; -; mRNA.
DR RefSeq; NP_001014230.1; NM_001014208.1.
DR AlphaFoldDB; Q5XIT3; -.
DR STRING; 10116.ENSRNOP00000012138; -.
DR PhosphoSitePlus; Q5XIT3; -.
DR PaxDb; 10116-ENSRNOP00000012138; -.
DR Ensembl; ENSRNOT00000012138.6; ENSRNOP00000012138.5; ENSRNOG00000022043.5.
DR Ensembl; ENSRNOT00065020134; ENSRNOP00065015451; ENSRNOG00065012359.
DR GeneID; 363027; -.
DR KEGG; rno:363027; -.
DR UCSC; RGD:1307512; rat.
DR AGR; RGD:1307512; -.
DR CTD; 78992; -.
DR RGD; 1307512; Yipf2.
DR eggNOG; KOG3114; Eukaryota.
DR GeneTree; ENSGT00390000010157; -.
DR HOGENOM; CLU_059606_1_1_1; -.
DR InParanoid; Q5XIT3; -.
DR OrthoDB; 8905at2759; -.
DR PhylomeDB; Q5XIT3; -.
DR TreeFam; TF313536; -.
DR PRO; PR:Q5XIT3; -.
DR Proteomes; UP000002494; Chromosome 8.
DR Bgee; ENSRNOG00000022043; Expressed in pancreas and 18 other cell types or tissues.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0005797; C:Golgi medial cisterna; ISS:UniProtKB.
DR GO; GO:0000138; C:Golgi trans cisterna; ISS:UniProtKB.
DR GO; GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR InterPro; IPR006977; Yip1_dom.
DR InterPro; IPR039765; Yip5/YIPF1/YIPF2.
DR PANTHER; PTHR12822:SF3; PROTEIN YIPF2; 1.
DR PANTHER; PTHR12822; UNCHARACTERIZED; 1.
DR Pfam; PF04893; Yip1; 1.
PE 2: Evidence at transcript level;
KW Acetylation; Endosome; Golgi apparatus; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250|UniProtKB:Q9BWQ6"
FT CHAIN 2..311
FT /note="Protein YIPF2"
FT /id="PRO_0000241456"
FT TOPO_DOM 2..120
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250|UniProtKB:Q9BWQ6"
FT TRANSMEM 121..141
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 142..159
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT TRANSMEM 160..180
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 181..198
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 220..226
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT TRANSMEM 227..247
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 248..252
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 253..273
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 274..311
FT /note="Lumenal"
FT /evidence="ECO:0000250|UniProtKB:Q9BWQ6"
FT MOD_RES 2
FT /note="N-acetylalanine"
FT /evidence="ECO:0000250|UniProtKB:Q9BWQ6"
SQ SEQUENCE 311 AA; 34798 MW; 5510D28D44CB6286 CRC64;
MAAADDLAFH EFEEAANLLA ETPDAATTSQ SDKLTSQEHV AVVVGSGIGY GAEGEEEDDK
TSLLQDEKPQ PRFWTFDYYQ SFFDVDTSQV LDRIKGSLLP HPGHNFVRHH LRNRPDLYGP
FWICATLAFV LAVTGNLTLV LAQRRDPSIH YSPQFHKVTI AGITIYCYAW LVPLALWGFL
RWRQGTRERM GLYTFLETVC VYGYSLFVFI PTVVLWLIPV QWLQWLFGAL ALALSAAGLV
FTLWPVVRED TRLVAAALLS IVVLLHALLA LGCKLYFFQP LPLDHVVPAP QAIPPSPNVL
LPSSVQPMTT F
//
