ID YL87_CAEEL Reviewed; 307 AA.
AC P34445; Q86D24;
DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2005, sequence version 3.
DT 27-MAR-2024, entry version 145.
DE RecName: Full=Uncharacterized protein F54C8.7;
GN ORFNames=F54C8.7;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=7906398; DOI=10.1038/368032a0;
RA Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA Wilkinson-Sproat J., Wohldman P.;
RT "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT elegans.";
RL Nature 368:32-38(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=b;
CC IsoId=P34445-1; Sequence=Displayed;
CC Name=a;
CC IsoId=P34445-2; Sequence=VSP_016114;
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DR EMBL; Z22178; CAA80157.2; -; Genomic_DNA.
DR EMBL; Z22178; CAD82913.1; -; Genomic_DNA.
DR PIR; S40749; S40749.
DR RefSeq; NP_001022604.1; NM_001027433.4. [P34445-2]
DR RefSeq; NP_871661.1; NM_181932.4. [P34445-1]
DR AlphaFoldDB; P34445; -.
DR SMR; P34445; -.
DR BioGRID; 41523; 3.
DR STRING; 6239.F54C8.7b.1; -.
DR EPD; P34445; -.
DR PaxDb; 6239-F54C8-7b; -.
DR PeptideAtlas; P34445; -.
DR EnsemblMetazoa; F54C8.7a.1; F54C8.7a.1; WBGene00010040. [P34445-2]
DR EnsemblMetazoa; F54C8.7b.1; F54C8.7b.1; WBGene00010040. [P34445-1]
DR GeneID; 176326; -.
DR KEGG; cel:CELE_F54C8.7; -.
DR UCSC; F54C8.7a; c. elegans. [P34445-1]
DR AGR; WB:WBGene00010040; -.
DR WormBase; F54C8.7a; CE28833; WBGene00010040; -. [P34445-2]
DR WormBase; F54C8.7b; CE33524; WBGene00010040; -. [P34445-1]
DR eggNOG; KOG3876; Eukaryota.
DR GeneTree; ENSGT00950000183040; -.
DR InParanoid; P34445; -.
DR OMA; AFTSHFY; -.
DR OrthoDB; 5166950at2759; -.
DR PhylomeDB; P34445; -.
DR Reactome; R-CEL-6811440; Retrograde transport at the Trans-Golgi-Network.
DR PRO; PR:P34445; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00010040; Expressed in germ line (C elegans) and 4 other cell types or tissues.
DR ExpressionAtlas; P34445; baseline and differential.
DR GO; GO:0005739; C:mitochondrion; HDA:WormBase.
DR GO; GO:0032588; C:trans-Golgi network membrane; IBA:GO_Central.
DR GO; GO:0005543; F:phospholipid binding; IBA:GO_Central.
DR GO; GO:0019904; F:protein domain specific binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:0034315; P:regulation of Arp2/3 complex-mediated actin nucleation; IBA:GO_Central.
DR CDD; cd07660; BAR_Arfaptin; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR010504; AH_dom.
DR InterPro; IPR030798; Arfaptin_fam.
DR PANTHER; PTHR12141:SF5; ARFAPTIN; 1.
DR PANTHER; PTHR12141; ARFAPTIN-RELATED; 1.
DR Pfam; PF06456; Arfaptin; 1.
DR SMART; SM01015; Arfaptin; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR PROSITE; PS50870; AH; 1.
PE 4: Predicted;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..307
FT /note="Uncharacterized protein F54C8.7"
FT /id="PRO_0000065360"
FT DOMAIN 91..291
FT /note="AH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00294"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..41
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..53
FT /note="MTGSTASPPEPSAPPADSPFAPVTQNDSSPTSDSTETMSRIPTGIKVPDVVA
FT N -> MGLLSKKNSIKLYRQNRQPLTTPVSKRPLEKCPR (in isoform a)"
FT /evidence="ECO:0000305"
FT /id="VSP_016114"
SQ SEQUENCE 307 AA; 33914 MW; A40C099A559370EF CRC64;
MTGSTASPPE PSAPPADSPF APVTQNDSSP TSDSTETMSR IPTGIKVPDV VANIDTAQVA
AKVESFKKWT IGTFKNSKQQ LLEHMGKIDK TVDPEFEAQC EVLKDIHRRY GLVVAAAKNF
SHVLTQMAEA EKKLSESFYQ LSMKEEQIKA QCTMTSETMR GVGEQAASLD ACLRYFISSM
ETVYNQTITD TLHTIYNTES ARIEYDVDRN DISAATNPPQ GQLTKNLPVG ATEKCEEKKA
KYEKLKNDAK IKMRLLEENR ISVVAAQLEK LQSALAAYYS GNAKLLEASV RELSFLQSPQ
PSFIPTM
//
