ID YSL13_ORYSJ Reviewed; 724 AA.
AC Q7XKF4; A3AVP5; Q0JBM3; Q3V7B8;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 2.
DT 24-JAN-2024, entry version 93.
DE RecName: Full=Probable metal-nicotianamine transporter YSL13;
DE AltName: Full=Protein YELLOW STRIPE LIKE 13;
DE Short=OsYSL13;
GN Name=YSL13; OrderedLocusNames=Os04g0524500, LOC_Os04g44300;
GN ORFNames=OsJ_014867, OSJNBb0065J09.15;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY, GENE FAMILY,
RP AND NOMENCLATURE.
RC STRAIN=cv. Nipponbare;
RX PubMed=15255870; DOI=10.1111/j.1365-313x.2004.02146.x;
RA Koike S., Inoue H., Mizuno D., Takahashi M., Nakanishi H., Mori S.,
RA Nishizawa N.K.;
RT "OsYSL2 is a rice metal-nicotianamine transporter that is regulated by iron
RT and expressed in the phloem.";
RL Plant J. 39:415-424(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [7]
RP TISSUE SPECIFICITY.
RX PubMed=19049971; DOI=10.1074/jbc.m806042200;
RA Inoue H., Kobayashi T., Nozoye T., Takahashi M., Kakei Y., Suzuki K.,
RA Nakazono M., Nakanishi H., Mori S., Nishizawa N.K.;
RT "Rice OsYSL15 is an iron-regulated iron(III)-deoxymugineic acid Transporter
RT expressed in the roots and is essential for iron uptake in early growth of
RT the seedlings.";
RL J. Biol. Chem. 284:3470-3479(2009).
CC -!- FUNCTION: May be involved in the transport of nicotianamine-chelated
CC metals. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q7XKF4-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q7XKF4-2; Sequence=VSP_036330;
CC -!- TISSUE SPECIFICITY: Expressed in leaves and at low levels in root
CC cortex. {ECO:0000269|PubMed:15255870, ECO:0000269|PubMed:19049971}.
CC -!- SIMILARITY: Belongs to the YSL (TC 2.A.67.2) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF15264.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=EAZ31384.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AB164644; BAE44204.1; -; mRNA.
DR EMBL; AL663010; CAE05719.2; -; Genomic_DNA.
DR EMBL; AP008210; BAF15264.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014960; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM000141; EAZ31384.1; ALT_FRAME; Genomic_DNA.
DR RefSeq; XP_015636359.1; XM_015780873.1.
DR AlphaFoldDB; Q7XKF4; -.
DR SMR; Q7XKF4; -.
DR STRING; 39947.Q7XKF4; -.
DR PaxDb; 39947-Q7XKF4; -.
DR GeneID; 4336441; -.
DR KEGG; osa:4336441; -.
DR eggNOG; ENOG502QQ2H; Eukaryota.
DR HOGENOM; CLU_015477_2_0_1; -.
DR InParanoid; Q7XKF4; -.
DR OrthoDB; 362380at2759; -.
DR Proteomes; UP000000763; Chromosome 4.
DR Proteomes; UP000007752; Chromosome 4.
DR Proteomes; UP000059680; Chromosome 4.
DR Genevisible; Q7XKF4; OS.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0035673; F:oligopeptide transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR004813; OPT.
DR InterPro; IPR045035; YSL-like.
DR NCBIfam; TIGR00728; OPT_sfam; 1.
DR PANTHER; PTHR31645:SF6; METAL-NICOTIANAMINE TRANSPORTER YSL13-RELATED; 1.
DR PANTHER; PTHR31645; OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED; 1.
DR Pfam; PF03169; OPT; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..724
FT /note="Probable metal-nicotianamine transporter YSL13"
FT /id="PRO_0000363876"
FT TRANSMEM 80..100
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 103..123
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 190..210
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 252..272
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 310..330
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 355..375
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 423..443
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 455..475
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 487..507
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 541..561
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 603..623
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 640..660
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 675..695
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..39
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 26..61
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_036330"
FT CONFLICT 53..54
FT /note="EE -> NK (in Ref. 6; EAZ31384)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 724 AA; 78767 MW; 5219423596C46F71 CRC64;
MATVPTPSEA HGGATPTAAD VEMVEASELR RRGKPSGDRA TGPSRDGAAA AAEEAAAPSV
ERVFADRPVP SWREQLTVRA FVVSFFLVIM FSVIVMKLNL TTGIIPSLNV SAGLLGFFFV
RLWTAAIERV GLLRQPFTRQ ENTVIQTCVV AGYDIAFSGG FGNYILSMSE RIAGLGTEAN
NAQNIKNPHL GWIIGFLFLV SFIGLFGLVP LRKVMIIDYK LTYPSGTATA FLINGFHTPH
GAKIAAKQVK KLGIFFILSF FWGFFQWFYT ATDDCGFHKF PSLGLQAFQH KFFFDFSPTY
VGVGMICPHI VNVSVLLGGI LSWGIMWPLI AKKRGDWFSA DLPDGSLHGM QGYRVFIAIA
LILGDGLYNF LKMIILTAFS LRSQIKKKNA STLPVSDDGM VTTTAAVSYD EERRNELFVK
DQIPWYVAYG GYAVVAAISI GTVPQIIPQL KWYQILVAYI VAPILAFCNA YGTGLTDWSL
VTTYGKLAIF AFGAWTGASH GGVLAGLAAC GVMMNIVSTA ADLMQDFKTG YLTLASPRSM
FVSQVIGTAM GCVIAPCVFW LFYKAFDNIG ISGSDYPAPN AAVFRSIAIL GVDGFSSLPK
NCLNLCYAFF AAAIVVNLIR DLVPKVSRFI PIPMAMAIPF YIGSYFAIDM FIGTVILFVW
QRVDRAKADT YGPAVASGMI CGDGIWVLPQ SVLALAKVKP PICMKFLSRR TNDKVDAFLT
TLGK
//
