ID Z9JJ04_9GAMM Unreviewed; 453 AA.
AC Z9JJ04;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=Magnesium transporter MgtE {ECO:0000256|RuleBase:RU362011};
GN ORFNames=AF72_08540 {ECO:0000313|EMBL:EWS77816.1};
OS Xylella taiwanensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Xylella.
OX NCBI_TaxID=1444770 {ECO:0000313|EMBL:EWS77816.1, ECO:0000313|Proteomes:UP000020406};
RN [1] {ECO:0000313|EMBL:EWS77816.1, ECO:0000313|Proteomes:UP000020406}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PLS229 {ECO:0000313|EMBL:EWS77816.1,
RC ECO:0000313|Proteomes:UP000020406};
RX PubMed=24652975;
RA Su C.C., Deng W.L., Jan F.J., Chang C.J., Huang H., Chen J.;
RT "Draft Genome Sequence of Xylella fastidiosa Pear Leaf Scorch Strain in
RT Taiwan.";
RL Genome Announc. 2:e00166-14(2014).
CC -!- FUNCTION: Acts as a magnesium transporter.
CC {ECO:0000256|RuleBase:RU362011}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|RuleBase:RU362011}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362011};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362011}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC41A transporter family.
CC {ECO:0000256|ARBA:ARBA00009749, ECO:0000256|RuleBase:RU362011}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EWS77816.1}.
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DR EMBL; JDSQ01000013; EWS77816.1; -; Genomic_DNA.
DR RefSeq; WP_038271466.1; NZ_VOSE01000003.1.
DR AlphaFoldDB; Z9JJ04; -.
DR STRING; 1444770.AF72_08540; -.
DR GeneID; 69681070; -.
DR KEGG; xtw:AB672_08435; -.
DR PATRIC; fig|1444770.3.peg.2021; -.
DR eggNOG; COG2239; Bacteria.
DR OrthoDB; 9790355at2; -.
DR Proteomes; UP000020406; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd04606; CBS_pair_Mg_transporter; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.25.60.10; MgtE N-terminal domain-like; 1.
DR Gene3D; 1.10.357.20; SLC41 divalent cation transporters, integral membrane domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR006668; Mg_transptr_MgtE_intracell_dom.
DR InterPro; IPR038076; MgtE_N_sf.
DR InterPro; IPR006669; MgtE_transporter.
DR InterPro; IPR006667; SLC41_membr_dom.
DR InterPro; IPR036739; SLC41_membr_dom_sf.
DR NCBIfam; TIGR00400; mgtE; 1.
DR PANTHER; PTHR43773; MAGNESIUM TRANSPORTER MGTE; 1.
DR PANTHER; PTHR43773:SF3; MAGNESIUM TRANSPORTER MGTE; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF01769; MgtE; 1.
DR Pfam; PF03448; MgtE_N; 1.
DR SMART; SM00924; MgtE_N; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF161093; MgtE membrane domain-like; 1.
DR SUPFAM; SSF158791; MgtE N-terminal domain-like; 1.
DR PROSITE; PS51371; CBS; 2.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Cell membrane {ECO:0000256|RuleBase:RU362011};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842, ECO:0000256|RuleBase:RU362011};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362011};
KW Metal-binding {ECO:0000256|RuleBase:RU362011};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362011};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362011};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362011}.
FT TRANSMEM 289..306
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362011"
FT TRANSMEM 318..342
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362011"
FT TRANSMEM 363..385
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362011"
FT TRANSMEM 391..412
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362011"
FT TRANSMEM 424..452
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362011"
FT DOMAIN 143..206
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 207..266
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 453 AA; 49621 MW; 883A533AC580AE5E CRC64;
MAETVHHDKT ARQLRLLSNA LDSGRFGPIR RLINTLSPAE IGNLLESLPP GKREVVWGMV
DQEDDGEVLL HVGDEVRESL LAAMDTDEII AAVEDLDIDD LADLVDDLPN TVIDQVLKSM
DRENRTRLEQ ALSYPEDSAG RLMNPDTVTV RADVNVDMVL RYLRLRGELP DHTDHLYVVS
RHHQYLGRVS LATLVTHEPD TPINRLIDNE QPAISIEEQA QEVARQFSYH DWLSAPVVNE
NNILLGRITI DDVVDIIREQ AEHQAMSAAG LSDDQDMFSP ARRAFRRRLL WLGINLCTAF
IAANVVSEFE YTIEKLVALA ALMPIVAGMG GNAGTQVLAL MIRGLALGQI STSNVLPLLK
KEMTVALING ICLGVSLGMI VLLWLKQPLL SLVIGSALTI NLCTAALGGV IIPMTLKRLG
FDPALAGGVI LTTLTDVIGF LSFLGLATLI LLH
//
