ID   Z9JKV3_9GAMM            Unreviewed;       352 AA.
AC   Z9JKV3;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=Hydroxyacid dehydrogenase {ECO:0000313|EMBL:EWS78397.1};
GN   ORFNames=AF72_05455 {ECO:0000313|EMBL:EWS78397.1};
OS   Xylella taiwanensis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Xylella.
OX   NCBI_TaxID=1444770 {ECO:0000313|EMBL:EWS78397.1, ECO:0000313|Proteomes:UP000020406};
RN   [1] {ECO:0000313|EMBL:EWS78397.1, ECO:0000313|Proteomes:UP000020406}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PLS229 {ECO:0000313|EMBL:EWS78397.1,
RC   ECO:0000313|Proteomes:UP000020406};
RX   PubMed=24652975;
RA   Su C.C., Deng W.L., Jan F.J., Chang C.J., Huang H., Chen J.;
RT   "Draft Genome Sequence of Xylella fastidiosa Pear Leaf Scorch Strain in
RT   Taiwan.";
RL   Genome Announc. 2:e00166-14(2014).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072, ECO:0000256|RuleBase:RU361277}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EWS78397.1}.
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DR   EMBL; JDSQ01000007; EWS78397.1; -; Genomic_DNA.
DR   RefSeq; WP_038270917.1; NZ_VOSE01000029.1.
DR   AlphaFoldDB; Z9JKV3; -.
DR   STRING; 1444770.AF72_05455; -.
DR   GeneID; 69682305; -.
DR   KEGG; xtw:AB672_02745; -.
DR   PATRIC; fig|1444770.3.peg.1303; -.
DR   eggNOG; COG1064; Bacteria.
DR   OrthoDB; 9771084at2; -.
DR   Proteomes; UP000020406; Unassembled WGS sequence.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd05283; CAD1; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR047109; CAD-like.
DR   InterPro; IPR029752; D-isomer_DH_CS1.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR42683; ALDEHYDE REDUCTASE; 1.
DR   PANTHER; PTHR42683:SF85; CINNAMYL ALCOHOL DEHYDROGENASE 6-RELATED; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
DR   PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Zinc {ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          13..342
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   352 AA;  37939 MW;  CE7380E462EA595A CRC64;
     MHVMSFAAQS ATGPLEQFAF ERRVPRSDDV VIDILYCGVC HTDLHLARNH SGFTTYPIVP
     GHEIIGRVRE IGETVTRFKA GDLVGVGCMV DSCQHCQPCL KGWEQDCIEG ATFTYNSADR
     QDGSITYGGY SDAIVVRDKF VLSLPDGLDP AGAAPLLCAG ITTWSPLRRW NVDKDSKVAV
     VGLGGLGHMA LKLAKALGAD VTLFTCSAGK EEDALRLGAD HVVLSGDLEQ MKAVYGRFDV
     IIDTVPYDHD VNPYMPTLAL EGVLVLVGYM GPLSTPVNAG GVVRGRRAIS GSFIGGVPET
     QQMLDFCGQH GIVSDVEIIP IQKINAAYER MLKSDVKYRF VIDMASLTSL GD
//