KEGG   Vibrio cholerae O1 2010EL-1786: Vch1786_I2177
Entry
Vch1786_I2177     CDS       T01650                                 
Symbol
metL
Name
(GenBank) bifunctional aspartate kinase II/homoserine dehydrogenase II
  KO
K12525  bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:2.7.2.4 1.1.1.3]
Organism
vce  Vibrio cholerae O1 2010EL-1786
Pathway
vce00260  Glycine, serine and threonine metabolism
vce00261  Monobactam biosynthesis
vce00270  Cysteine and methionine metabolism
vce00300  Lysine biosynthesis
vce01100  Metabolic pathways
vce01110  Biosynthesis of secondary metabolites
vce01120  Microbial metabolism in diverse environments
vce01230  Biosynthesis of amino acids
Module
vce_M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
vce_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
vce_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:vce00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    Vch1786_I2177 (metL)
   00270 Cysteine and methionine metabolism
    Vch1786_I2177 (metL)
   00300 Lysine biosynthesis
    Vch1786_I2177 (metL)
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    Vch1786_I2177 (metL)
Enzymes [BR:vce01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     Vch1786_I2177 (metL)
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.4  aspartate kinase
     Vch1786_I2177 (metL)
SSDB
Motif
Pfam: Homoserine_dh AA_kinase NAD_binding_3 DUF4892 ELFV_dehydrog
Other DBs
NCBI-ProteinID: AET27761
Position
1:2321646..2324057
AA seq 803 aa
MTHPRQLHKFGGSSLADPECYQRVAKILKSYSKSDDLVVVSAAGKTTNRLISFVEALSKD
GRVAHETLHALRQYQSELITKLLSNEAAEPLLSQLQQEISVLGELTAPLSNAQYAWVLGH
GELWSARLLAALLNQQDLPAVAQDARTFLRAEAGTQPEVDRARSYPLLKAVLAQHTQRRV
VITGFMAQNEQGDTVLLGRNGSDYSATVIGALAEVSRVTIWSDVAGVYSADPRIVSDACL
LPLLRLDEANELARLAAPVLHSRTLQPVAQSTMELHLRCSHQPESGSTRIERVLASGRGA
KIITSLDDVLLIELSFAHHHDFQRVQEDVLQHLQRVQLQPLTYEAQPDQYRLRLAYTAEI
APGAFAALQDAAFEAEIKLKEGYDLIAAVGAGVTKNPNHCYGFYQQLNALPVEFISASES
SLSLVAVLRQTPIHSLVNAIHKQLFQAQKHVAIALCGKGNIGSSWLKLFAEQKEKLEQRH
GMNFELVAVVDSQTYWFNEQGINPNQVATHFQDEALPNQEQSWLKKLGALEGYDEAVVID
VTASEELAEQYLDIAEHGLHLISANKVAGSAAGNYYYQVKDAFHKIGRHWLYNATVGAGL
PINHTVRDLRESGDDIMALSGIFSGTLSWLFQQYDGSLPFSELVDLAWQQGLTEPDPRCD
LDGSDVMRKLVILARESGLEIEPQNVKVESLVPAELRSVSLDDFLDNSKLLNEQLAERLA
RAQKQGKVLRYVARLEKNGKASVGVEALEQDHPLANLLPCDNIFAIESKWYRDNPLVIRG
PGAGREVTAGAIQSDLNLLASLL
NT seq 2412 nt   +upstreamnt  +downstreamnt
atgacccatccccgtcaattgcataaatttggtggtagtagccttgccgaccctgagtgt
tatcaacgtgtcgcgaaaattcttaaaagttattccaaaagtgatgatctggtggtggtt
tctgcggctggcaaaaccactaaccgtttgatcagttttgtcgaagcactcagtaaagat
ggtcgcgttgcccatgaaaccttacatgcgctgcgccaatatcagtctgaattgattact
aagctactcagcaacgaagcagccgaaccactacttagccaactgcaacaagagatcagc
gtgttaggcgagctcacagctcctcttagtaacgcacaatacgcttgggttttaggacat
ggtgagctctggtcggcacgcctgctcgccgcgttactgaaccagcaagatttaccagcg
gtcgcacaagatgcgcgaacatttttacgtgccgaagcaggcacacagccggaagtcgat
cgcgcgcgctcttacccactactgaaagccgtgttggcacaacatacccagcgccgcgtg
gtgatcaccggttttatggcgcaaaacgaacagggcgatactgtcctgctcggtcgtaac
ggttccgattattctgcgaccgtgattggcgcactggctgaagtctcacgcgtgaccatt
tggagtgatgtggctggcgtgtacagtgccgatccacgcattgtcagcgatgcctgtttg
ctgccactgctaagactcgatgaagccaatgagctggcacgcttagctgcgccagttctg
cacagccgtacactccaacctgtcgcgcagagcaccatggagcttcacttacgttgcagc
caccaaccggaatcgggctctacccgtattgaacgggtactggcttctggtcgcggcgcg
aaaatcattacttcgctcgatgatgtgctgctgattgagctgagctttgctcatcaccat
gatttccaacgtgtgcaagaagatgtgttacagcacttgcagcgcgtgcaactgcaaccg
ctgacttacgaagcacaacctgaccaataccgtttgcgtttagcctacacagcagaaatt
gcgcctggcgcgtttgcggcgctgcaagatgccgcgttcgaggcggaaatcaaactcaaa
gaaggctatgacctgattgctgcggtcggtgcgggcgtcactaaaaacccgaaccactgt
tatggcttctaccaacagctgaatgccttaccggtcgagtttatcagcgcgtcagaatca
agcctcagtttggttgccgtactgcgtcaaacgccgattcattcattggttaacgccatt
cacaaacagctcttccaagctcaaaaacacgtcgcgattgcgctgtgtggcaaaggcaat
attggctccagctggctcaagttgtttgccgaacaaaaagagaaattggaacaacgccac
ggcatgaattttgagttggttgcggtagtcgatagccaaacctactggtttaatgagcaa
ggcattaatccaaaccaagtggccacgcatttccaagatgaagcactgcccaaccaagag
caaagctggctgaaaaaactcggcgcattagaagggtacgatgaagccgtcgtgattgat
gtcaccgccagcgaagagttagctgagcagtatctcgatattgccgaacacggtttgcac
ctgatttccgccaacaaagtggcaggctctgctgcggggaattattactatcaagttaaa
gatgcctttcacaaaattggccgccactggctgtataacgccacggtaggcgcgggctta
ccaattaaccacacggtgcgtgacctacgtgaaagcggcgatgacatcatggcgttatcc
gggattttctccggcacactctcatggctgttccagcaatacgacggcagcttgccattc
agtgaactggtggatttagcatggcaacaaggcttaacagagcccgatccgcgctgcgat
ctcgacggttctgatgtcatgcgtaaattggtgatcttggcgcgtgaatctggccttgag
attgagccgcagaatgtcaaagtggaatcattggtacctgccgagctgcgctctgtatca
ctggatgattttctcgataacagcaaactgctcaacgagcagctcgccgaacgcctcgcc
cgtgcgcagaagcaaggcaaggtgctgcgctacgtcgcaaggctagagaaaaatggcaaa
gccagcgtgggtgtagaagcgcttgagcaagatcatccactggctaacttactgccgtgt
gacaacatctttgccatcgagagcaaatggtatcgcgataatccattggtgatccgaggt
cccggcgctggacgtgaagtcaccgctggcgcgattcagtcggatttgaatctgctcgcg
agcctactctaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (8)   
   KEGG MODULE (5)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (5)   
   Pfam (5)   
All databases (40)   

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