KEGG   Micromonospora maris: VAB18032_24830
Entry
VAB18032_24830    CDS       T01471                                 
Name
(GenBank) beta-ketoacyl synthase
  KO
K15320  6-methylsalicylic acid synthase [EC:2.3.1.165]
Organism
vma  Micromonospora maris
Pathway
vma01059  Biosynthesis of enediyne antibiotics
vma01100  Metabolic pathways
vma01110  Biosynthesis of secondary metabolites
Module
vma_M00829  3,6-Dimethylsalicylyl-CoA biosynthesis, malonyl-CoA => 6-methylsalicylate => 3,6-dimethylsalicylyl-CoA
Brite
KEGG Orthology (KO) [BR:vma00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01059 Biosynthesis of enediyne antibiotics
    VAB18032_24830
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins [BR:vma01008]
    VAB18032_24830
Enzymes [BR:vma01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.165  6-methylsalicylic-acid synthase
     VAB18032_24830
Polyketide biosynthesis proteins [BR:vma01008]
 Polyketide synthase (PKS)
  Iterative type I PKS
   Fungal partially reducing PKS (PR-PKS)
    VAB18032_24830
SSDB
Motif
Pfam: ketoacyl-synt Acyl_transf_1 KR Ketoacyl-synt_C KAsynt_C_assoc PP-binding PKS_DH_N adh_short Thiolase_N adh_short_C2 ACP_syn_III
Other DBs
NCBI-ProteinID: AEB46064
UniProt: F4FD34
Position
4510619..4515790
AA seq 1723 aa
MSLEPIAIVGMACRFAGGIDSPDAFWEMLCDGRDAVGDLPAGRWDWYAQQGREHATAVRS
ATSRGAFLDDIAGFDADFFGVTPREATLMDPQQRMVLELAWEALEHAGIPPGQLAGTDTG
VYVGVGADDYGRRMLEDLPRIEAWTGVGGGYCGVANRVSYLLDLRGPSMVLDTACSSSLV
AVHLAAQALRNGECPVALAGGVLVIAAPGLSLVLDAAGATAPDGRSKAFDAAADGYGRGE
GGGVVVLKRLADARRDGDRVLAVLRGSAVHQDGRTDGIMAPSAQAQAHLLRRAYQNAGVD
PSTVGYVEAHGTGTRAGDPLEAQAMSAVLGAGRPADRPLLIGSAKTNIGHLEAGAGVAGL
IKAVLTLRHGVIPPSLHVHTPNPAIPWDTAGLKVVTELTPWVQTEGPRRAGVCGYGYGGT
IAHVILEAADEQPAADEQSATDVPDPATPQPALYPLSGASAAAVGQYAARLADRLDRPHP
PALADVGYTLARRRDELPYRATVVAADRTELVERLRALAAPSGVGEIGRASAPAGRGVVW
VFSGHGSQWIGMGRELLHAEPVFAEVLDELEPIFQAELDVSPGAALRAQTAHPVDVIQPL
IFAVQVALAAVLRAHGAHPAAVLGHSVGEIAAAVTAGLLTREQGARLVCRRSVLLRRVAG
QGAMAMVDLPPEEAEQRLTDDGDVCVAIAASPVATVISGSAAAVRAVSRRWADEGLDVRM
VDSDVAFHSSQMDELTADLAAACADLPPAEVPTVAVYSTASTDSRTAAPRDGAYWAANLR
EQVRLAQAVEAAAADGYRLFLEVSAHPVVTHSIAETLDLLGVEDTLVAHTLRRHRPERES
LLGAVGRLWRHGAPLDWAGPWPTGSTTALPPIAWQHRPFWYDEPSVRSFLTEQHDPEGHT
VLGGRITVRGATPAHAWMTYLDRDSRPYPGDHPVRGVEILPAAVLLHTFLTAAETLVGAR
PELTDVALRVPVSVTAARYLQVVHQDGIVRLSSRIADGDESAWTTHTTAVVVAAPAVVDP
EPVLSVPTGGRLPTTYVVDRLAELGVAAMGFHWRVEQLRRDGRTLTALVDAGDPAGGWAP
VLDAALSIASVAFDGPPILRMPAHIGRVSLGPVAPQRVRVVVHRADDDTLTVEIAELGGV
VLGRLHRLRYGTLDQDSDAVTDPRNLLHEVAWTPAETHQGGHRPPARVLLVGPPSALRDR
VAAALRVAGVHWSTVSGPAELPSTVAGTVIVVPGPGVGGEPAAQAAWLLAQTAQRLAEAR
SDGTRLWCVTEGVRESVDPSALGHAALWGLGRIVAGEHPTLWGALVDVGTDPADLGTFVG
LLGGRPADPLVAVRDGRVTVPRLRPLTEPSTRPPLVCRPEATYLITGGLGALGLTVARWL
ADRGARRLVLAGRHTPPPRDTWHTLTDARDRAVVDAIDALERLGVTVVTAQVDVADPTAL
AELSSSAPLGLPPIRGVVHAAGVLDNRTLLELDEPSLRAVLRPKVDGALALHHRFPPGEL
DLFVLFSSCGGLLGLPGQASYAAGNAFLDALAAHRRAAGDVGTLSLAWTSWRGLGMSTSS
EVIDLELAARGTGDISAAEALGAWELAARQDREHAVVLRTLPPAPGTQRPALLSELTAPA
AAAPPTESEAWRELAGGTLREFLADTVRGEVVATTGLSAAEIDDRQPLTELGLDSVMTVR
IRRNLERRLAMSLPATIFWERPSVDAVTELLADLVGAVAEEAQ
NT seq 5172 nt   +upstreamnt  +downstreamnt
gtgtcgctggaaccgatcgccatcgtcggaatggcctgccgcttcgccggcgggatcgac
tccccggacgccttctgggagatgctctgcgacgggcgcgacgccgtcggcgacctgccc
gcgggccgctgggactggtacgcccagcagggccgggagcacgccacggccgtgcggtca
gcgaccagccggggcgcgttcctggacgacatcgcgggcttcgacgcggacttcttcggc
gtcaccccacgggaggccacgctgatggacccgcagcagcggatggtgctggagctggcc
tgggaggcgttggaacacgcggggattccgccgggacagctggccggcaccgacaccggc
gtctacgtcggcgtcggcgccgacgactacggccggcggatgctggaggacctgccccgg
atcgaggcgtggaccggcgtcggcggtggctactgcggcgtggccaaccgggtctcctat
ctgctggatctgcggggcccgagcatggtgctggacaccgcctgctcgtcgtcgcttgtc
gccgtgcacctggccgcgcaggcgctgcgcaacggggagtgcccggtggcgctcgccggc
ggggtcctggtgatcgccgcaccgggtctgtcgctggtgctcgacgccgccggcgccacc
gcccccgacggtcgcagcaaggcgttcgacgccgccgccgacgggtacggccggggcgag
ggcggcggggtcgtcgtactcaagcggttggccgacgcccggcgcgacggtgaccgggtg
ctggccgtgctccggggcagcgcggtgcaccaggacggccgcaccgacgggatcatggcc
ccgagcgcgcaggcccaggcccacctgctccgccgggcgtaccagaacgcgggggtggac
ccgtcgaccgtcggctacgtggaggcgcacggcaccgggacccgggccggcgacccgctg
gaggcgcaggcgatgtcggcggtgctcggggccggacgccccgccgaccgacccctgttg
atcggctcggccaagacgaacatcgggcacctggaggccggcgccggagtggccggactg
atcaaggcagtgctcacgctgcgacacggcgtcatcccgccgagcctgcacgtgcacacc
ccgaacccggccatcccgtgggacaccgccggcctgaaggtggtcaccgaactcaccccc
tgggtgcagaccgagggtccccggcgcgcgggcgtctgcggctacgggtacggcggcaca
atcgcccacgtcatcctggaggccgccgacgagcagccagccgccgacgagcaatcggcc
accgacgtgcccgacccggcgacaccgcagccggcgctgtaccccctctccggcgcgtcc
gccgccgccgtcggccagtacgccgcccgcctggccgaccggctcgaccgcccgcacccg
cccgccctcgccgacgtcgggtacaccctggcccgccgccgcgacgagctgccgtaccgg
gccaccgtggtcgccgcggaccgcaccgaactggtcgagcggctgcgcgcgctggccgcc
ccgagcggcgtcggcgagatcggccgcgcctccgcaccggccggtcggggcgtggtctgg
gtcttctccggtcacggctcacagtggatcgggatgggtcgcgagctgctgcacgccgaa
ccggtgttcgcggaggtgctcgacgaactcgaaccgatcttccaggcggagctggacgtc
tcgcccggcgcggcgttgcgggcgcagaccgcccacccggtcgacgtgatccagccgctg
atcttcgcggtccaggtggcgctcgccgcggtgctgcgcgcacacggcgcgcacccggcc
gcggtgctcggacactcggtgggtgagatcgccgcggcggtcaccgccggcctgctcacc
cgggaacagggggcccggctcgtctgccgacgctcggtgctgctgcgtcgggtggccggg
cagggcgcgatggcgatggtggacctgccacccgaggaggccgaacagcggctcaccgac
gacggcgacgtctgcgtggcgatcgccgcctcgccggtcgcgacggtgatctccggttcg
gcggcagcggtccgcgcggtcagtcgccggtgggccgacgagggcctcgacgtccggatg
gtcgactccgacgtggccttccacagctcgcagatggacgagctgaccgccgacctcgcc
gccgcctgcgccgacctgccgccggccgaggttccgaccgtcgcggtctactccacggcg
tcgaccgacagccgcaccgccgcaccgcgcgacggcgcgtactgggcggccaatctgcgc
gagcaggtgcgtctggcgcaggccgtcgaggccgccgcggccgacgggtaccgactgttc
ctggaggtgtccgcgcacccggtcgtgacgcactcgatcgccgagacgctcgacctgctc
ggcgtcgaggacaccctggtggcgcacacgctgcgccggcaccgcccggaacgggagagc
ctgctcggcgcggtgggccggctgtggcggcacggcgcaccgctggactgggcgggaccg
tggccgaccgggtcgacgaccgccctgccgccgatcgcctggcagcatcgcccgttctgg
tacgacgagccgtcggtgcggtccttcctgaccgagcagcacgaccccgagggccacacg
gtgctcggcggccggatcaccgtgcgaggggcgacaccggcgcacgcctggatgacctac
ctcgaccgggactcccggccgtacccgggcgaccacccggtccggggggtggagatcctg
ccggccgcggtgctgctgcacaccttcctgaccgccgccgagacgctggtgggggcgcgc
cccgagttgaccgacgtggccctgcgggtgccggtcagcgtgacggccgcccggtacctg
caggtggtgcatcaggacgggatcgtccgactgtcctcgcggatcgccgacggcgacgag
tccgcctggaccacccacacgacggcggtggtggtggcagcgccggccgtcgtcgacccc
gagccggtgctgtccgtaccgaccggcgggcggctgcccaccacgtacgtggtggaccgc
ctcgccgaactcggtgtcgccgcgatgggtttccactggcgggtcgagcagctgcgccgg
gacggccggacgcttaccgccctcgtggacgccggagatccggcgggaggctgggcaccg
gtcctcgacgccgcgctgtcgatcgcctcggtggccttcgacgggccgcccatcctgcgc
atgccggcgcacatcggccgggtcagcctcggcccggtcgccccgcagcgggtccgggtc
gtggtccatcgtgccgacgacgacacgttgaccgtcgagatcgccgaactcggcggggtg
gtcctcggccggctgcaccggttgcggtacggcaccctcgaccaggacagcgacgcggtc
accgatccccgcaacctgctgcacgaggtcgcctggacacctgcggaaacacaccagggc
gggcaccggccaccggcgcgggtgctgctggtcggcccgccgagcgccctgcgggaccgg
gtggccgcggcactgcgggtggccggggtgcactggagcacggtcagcgggccggcggag
ctgccgtccacagttgccggcacggtgatcgtcgtaccggggcccggtgtcggcggcgag
ccggccgcccaggcggcctggctgctcgcgcagaccgcgcagcgtctcgccgaggcccgg
tcggacggcacccgactctggtgcgtgaccgagggggtccgggagagtgtggacccgtcg
gcgctcggccacgccgccctgtgggggctgggccgcatcgtggccggcgagcatcccacc
ttgtggggtgcgcttgtcgacgtcggcaccgatccggccgacctcggcacgttcgtcggc
ctgctcggcggccggcccgccgacccgctcgtcgcggtcagggacggccgggtgacggtg
ccccggctccgcccgctcaccgaaccatcgacccgtcccccgctggtctgccgccccgag
gcgacatacctgatcaccggtgggctcggtgccctcggcctgacggtggcccgttggctg
gccgaccgtggcgcacgtcggctcgtgctggccggacgccacaccccgccgccccgggac
acctggcacacgctcaccgatgcgcgggatcgggccgtggtcgacgccatcgacgcgctg
gaacgactcggggtcaccgtggtgaccgcccaggtggacgtcgccgatccgacggcgctc
gcggaactgtcgtcttcggcaccgctcgggctgccgccgatccggggcgtcgtgcacgcc
gccggggtgctggacaaccgcaccctgctggaactcgacgagccctcgttgcgcgcggtg
ctgcgtcccaaggtcgacggggcgctggcgctgcaccaccggttcccgcccggcgaactg
gacctgttcgtgctcttctcctcctgcggcggactgctcgggctgcccggtcaggcgagt
tacgccgccggcaacgccttcctcgacgcgctcgcggcccaccgtcgcgcggccggtgac
gtcggcacgctcagcctggcctggacgtcgtggcgagggctcggcatgtccacctccagc
gaggtgatcgacctggagctggccgcgcgtggcaccggcgacatcagcgccgccgaggcc
ctcggcgcctgggagctggccgcccggcaggaccgggagcacgccgtggtgctgcgaacg
ctgccaccggcccccgggacgcagcggccggccctgctcagcgagctgaccgcgccggcc
gccgccgcgccgccgacggagagcgaggcctggcgcgagctggccggcgggacgctgcgg
gagttcctggccgacacggtacgcggcgaggtggtcgcgaccaccggcctgtccgcagcg
gagatcgacgaccggcagccgctgaccgaactcggcctggactcggtgatgaccgtccgg
atccgacggaacctggaacgccggctcgccatgtcgttgccggccaccatcttctgggag
cggccgagcgtggacgcggtgaccgaactgttggccgatctggtcggcgcggtggcggag
gaggcgcagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (39)   
   KEGG ORTHOLOGY (1)   
   RefGene (36)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (11)   
   Pfam (11)   
All databases (70)   

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