KEGG   Vulpes vulpes (red fox): 112911890
Entry
112911890         CDS       T05911                                 
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2-like
  KO
K05859  phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
Organism
vvp  Vulpes vulpes (red fox)
Pathway
vvp00562  Inositol phosphate metabolism
vvp01100  Metabolic pathways
vvp01521  EGFR tyrosine kinase inhibitor resistance
vvp04012  ErbB signaling pathway
vvp04014  Ras signaling pathway
vvp04020  Calcium signaling pathway
vvp04062  Chemokine signaling pathway
vvp04064  NF-kappa B signaling pathway
vvp04066  HIF-1 signaling pathway
vvp04070  Phosphatidylinositol signaling system
vvp04072  Phospholipase D signaling pathway
vvp04360  Axon guidance
vvp04370  VEGF signaling pathway
vvp04380  Osteoclast differentiation
vvp04611  Platelet activation
vvp04613  Neutrophil extracellular trap formation
vvp04625  C-type lectin receptor signaling pathway
vvp04650  Natural killer cell mediated cytotoxicity
vvp04662  B cell receptor signaling pathway
vvp04664  Fc epsilon RI signaling pathway
vvp04666  Fc gamma R-mediated phagocytosis
vvp04670  Leukocyte transendothelial migration
vvp04722  Neurotrophin signaling pathway
vvp04750  Inflammatory mediator regulation of TRP channels
vvp04919  Thyroid hormone signaling pathway
vvp04933  AGE-RAGE signaling pathway in diabetic complications
vvp04935  Growth hormone synthesis, secretion and action
vvp05167  Kaposi sarcoma-associated herpesvirus infection
vvp05169  Epstein-Barr virus infection
vvp05170  Human immunodeficiency virus 1 infection
vvp05171  Coronavirus disease - COVID-19
vvp05200  Pathways in cancer
vvp05205  Proteoglycans in cancer
vvp05206  MicroRNAs in cancer
vvp05214  Glioma
vvp05223  Non-small cell lung cancer
vvp05225  Hepatocellular carcinoma
Module
vvp_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:vvp00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    112911890
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    112911890
   04014 Ras signaling pathway
    112911890
   04370 VEGF signaling pathway
    112911890
   04064 NF-kappa B signaling pathway
    112911890
   04066 HIF-1 signaling pathway
    112911890
   04020 Calcium signaling pathway
    112911890
   04070 Phosphatidylinositol signaling system
    112911890
   04072 Phospholipase D signaling pathway
    112911890
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    112911890
   04613 Neutrophil extracellular trap formation
    112911890
   04625 C-type lectin receptor signaling pathway
    112911890
   04650 Natural killer cell mediated cytotoxicity
    112911890
   04662 B cell receptor signaling pathway
    112911890
   04664 Fc epsilon RI signaling pathway
    112911890
   04666 Fc gamma R-mediated phagocytosis
    112911890
   04670 Leukocyte transendothelial migration
    112911890
   04062 Chemokine signaling pathway
    112911890
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    112911890
   04919 Thyroid hormone signaling pathway
    112911890
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    112911890
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    112911890
  09158 Development and regeneration
   04360 Axon guidance
    112911890
   04380 Osteoclast differentiation
    112911890
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    112911890
   05206 MicroRNAs in cancer
    112911890
   05205 Proteoglycans in cancer
    112911890
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    112911890
   05214 Glioma
    112911890
   05223 Non-small cell lung cancer
    112911890
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    112911890
   05171 Coronavirus disease - COVID-19
    112911890
   05167 Kaposi sarcoma-associated herpesvirus infection
    112911890
   05169 Epstein-Barr virus infection
    112911890
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    112911890
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    112911890
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:vvp04131]
    112911890
Enzymes [BR:vvp01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     112911890
Membrane trafficking [BR:vvp04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    112911890
 Endocytosis
  Macropinocytosis
   Phospholipase C
    112911890
SSDB
Motif
Pfam: PI-PLC-X SH2 PH PH_12 PH_14 GDPD EF-hand_like
Other DBs
NCBI-GeneID: 112911890
NCBI-ProteinID: XP_025844363
UniProt: A0A3Q7RGE6
Position
Unknown
AA seq 867 aa
MTALVHVDSLPEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKAVRQKEECCFTILYGTQFVLSTLSLAADSKEDAN
KWLSGLKILHQEAMSASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVNSA
KFLKDKFVEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VHLHDFQRFLLHEQQELWAQDLNKVRARMTKFIDDTMRETAEPFLFVDEFLTYLFSRENS
IWDEKYDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCCVEQQRHMARV
FKEVFGDQLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHKQQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTAEEELPQDIPPTELHFGEEWFHKKVEKR
TSAEKLLQEYCAETGGKDGTFLVRESKTFPNDYTLSFWRSGRVQHCRIRSTVEGGTMKYF
LTDNVTFTSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDGLSRGEAEDML
MRVPRDGAFLIRRREGTDSYAITFRARGKVKHCRIHRDGRHFVLGTSAYFESLVELVSYY
EKHALYRKMRLRYPVTPELLERYNMHLPTKALQCPLFSSRWKGDYGTRIQQYFPSNYVED
ISTVDVEELEKQIIEDNPLGSLCRGILDLNTYNVVKAPQGKNQKPFVFILEPKKQGDPPV
EFATDKVEELFEWFQSIREITWKIDTK
NT seq 2601 nt   +upstreamnt  +downstreamnt
atgactgccctggtccacgtggacagccttccggaatacgagaagagtcagatcaagaga
gccctagagctgggcacggtgatgacggtgttcagcttccgcaagtccaccccagagcgg
aggaccgtccaggtgatcatggagacgcgccaggtggcctggagcaagacagccgacaag
atcgagggcttcttggatatcatggaaatcaaggaaatccgcccagggaagaactccaag
gattttgagcgtgccaaagcagtccgccagaaggaagagtgctgttttaccatcttgtac
ggcacccagtttgttctgagcacactcagtctggcagctgactctaaagaagatgcgaat
aagtggctctctggcttgaaaatcttacaccaggaagcgatgagtgcatctacacccacc
attattgagagttggctgagaaagcagatttattcagtggaccaaaccagaagaaacagc
atcagcctccgagagttgaagaccatcttacccctggtcaactttaaggtgaacagtgcc
aagttcctcaaagataagtttgtggaaattggtgcacacaaagatgagctcagctttgag
cagttccacctgttctataaaaaacttatgtttgagcagcaaaagtcgattcttgatgaa
ttcaaaaaagattcttccgtgttcatcttgggcaacactgaccggccggacgcctctgct
gttcacctgcacgacttccagcgctttctcttacatgagcaacaggagctttgggctcag
gatctgaacaaagtccgtgcgcggatgacaaagtttatcgatgacaccatgagggaaacg
gccgagcccttcttgtttgtcgatgagttcctcacgtatctgttttcgcgggagaacagc
atctgggatgagaagtacgacgtggtggacatgcaggacatgaacaaccccttgtcccat
tactggatctcctcttcgcataacacgtacctcactggtgaccagctacggagtgagtca
tccacagaagcgtacatccgttgcctgcggatgggctgtcgctgcattgagttggactgc
tgggacgggcccgacgggaagcccatcatctaccacggctggacacggaccaccaagatc
aagtttgatgacgttgtgcaggccatcaaagaccatgcctttgtcacttcaagcttcccc
gtgatcctgtccatcgaggagcactgttgcgtggagcagcagcgccacatggccagggtg
ttcaaggaggtgtttggcgaccagctgctgacgaagcccacagaggccagtgctgaccag
ctgccctcccccagccagttgcgggagaagatcatcatcaagcataagaagctgggtccc
cgaggggacgtggatgtcaacatggaggacaagaaagatgagcacaagcaacagggtgaa
ctgtatatgtgggattccatcgaccagaaatggactcgacactactgtgccatcgccgat
gccaaactgtctttcagcgatgacattgagcagactgcagaagaggagctgccccaggac
ataccccccacggagctgcattttggggaggagtggttccacaagaaagtagagaagagg
acgagtgccgagaagctgctgcaggaatactgtgcagagaccgggggcaaggatgggact
ttccttgtgcgggagagcaagaccttccccaatgactacaccctgtccttctggcggtcg
ggccgtgtccagcactgccggatccgttccaccgtggaggggggcaccatgaagtacttc
ctgactgacaacgtcacgttcaccagcatctacgccctcatccagcactaccgcgagacc
cacctgcgctgcgccgagttcgagctgcggctcaccgaccctgtgcccaaccccaacccc
cacgagtccaagccgtggtactacgacgggctgagccgtggggaggcagaggacatgcta
atgagggtgccccgggacggcgccttcctgatccggaggcgagaaggtaccgactcctat
gccatcaccttcagggccaggggcaaggtgaagcactgccgcattcaccgggatggccgg
cactttgtgctggggacctctgcctacttcgagagcctcgtggagctagtcagctactac
gaaaagcacgcgctctaccgaaaaatgcgactgcgctaccccgtgacgcctgagctcctg
gagcgctacaatatgcacctgcccacgaaggccctccagtgccctctgttttcatctagg
tggaagggggactatggaaccagaatccagcagtacttcccatccaattacgtcgaggac
atttcaacagtcgacgtggaggagctggagaagcagattattgaagacaatcccttaggg
tctctttgtaggggaatactggatctcaatacctataacgttgtgaaagccccccagggg
aaaaaccagaagccattcgtgtttatcctggagcccaagaagcaaggcgaccccccagta
gagtttgccacggacaaggtggaggagctctttgagtggtttcagagcatccgggagatc
acctggaagatagacaccaag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (38)   
   KEGG PATHWAY (37)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (67)   

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