KEGG   Vulpes vulpes (red fox): 112924977
Entry
112924977         CDS       T05911                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
vvp  Vulpes vulpes (red fox)
Pathway
vvp04010  MAPK signaling pathway
vvp04015  Rap1 signaling pathway
vvp04218  Cellular senescence
vvp04620  Toll-like receptor signaling pathway
vvp04664  Fc epsilon RI signaling pathway
vvp04668  TNF signaling pathway
vvp04714  Thermogenesis
vvp04750  Inflammatory mediator regulation of TRP channels
vvp04912  GnRH signaling pathway
vvp04935  Growth hormone synthesis, secretion and action
vvp04936  Alcoholic liver disease
vvp05014  Amyotrophic lateral sclerosis
vvp05022  Pathways of neurodegeneration - multiple diseases
vvp05132  Salmonella infection
vvp05135  Yersinia infection
vvp05145  Toxoplasmosis
vvp05161  Hepatitis B
vvp05169  Epstein-Barr virus infection
vvp05170  Human immunodeficiency virus 1 infection
vvp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
vvp05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:vvp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112924977 (MAP2K3)
   04015 Rap1 signaling pathway
    112924977 (MAP2K3)
   04668 TNF signaling pathway
    112924977 (MAP2K3)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    112924977 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    112924977 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    112924977 (MAP2K3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    112924977 (MAP2K3)
   04935 Growth hormone synthesis, secretion and action
    112924977 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    112924977 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    112924977 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    112924977 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    112924977 (MAP2K3)
   05161 Hepatitis B
    112924977 (MAP2K3)
   05169 Epstein-Barr virus infection
    112924977 (MAP2K3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    112924977 (MAP2K3)
   05135 Yersinia infection
    112924977 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    112924977 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    112924977 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    112924977 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    112924977 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    112924977 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:vvp01001]
    112924977 (MAP2K3)
Enzymes [BR:vvp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     112924977 (MAP2K3)
Protein kinases [BR:vvp01001]
 Serine/threonine kinases: STE group
  STE7 family
   112924977 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Haspin_kinase Pkinase_fungal APH Choline_kinase RIO1 DUF4344
Other DBs
NCBI-GeneID: 112924977
NCBI-ProteinID: XP_025861448
UniProt: A0A3Q7SWT4
Position
Unknown
AA seq 347 aa
MESPASSQPASMPQPKGKSKRKKDLRISCMSKPPVPNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTLDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtcccccgcctccagtcagcccgctagcatgccccagcccaaagggaaatccaag
aggaagaaggatttacggatatcctgcatgtccaagccacctgtacccaaccccacaccc
ccccggaacctcgactcccggaccttcatcaccattggagataggaactttgaggtggag
gccgatgacctggtgaccatctcagagctgggccgaggagcctacggggtggtagagaag
gtgcgacatgcccagagtggcaccatcatggccgtgaagcggatccgggccaccgtgaac
tcacaggagcagaagcgtctgctcatggacttggacatcaacatgcggactgtcgactgc
ttctataccgtcaccttctatggggccctcttcagagagggagatgtgtggatctgcatg
gagctcatggacacatccctggacaagttctaccggaaggtgctcgataaaaacatgacc
attccagaggacatcctgggggaaattgctgtgtctatcgtgagggcgctggagcacctg
cacagcaagctgtcggtgatccatagagatgtgaagccgtccaatgtcctcatcaacaag
gagggccacgtgaagatgtgcgactttgggattagtggttacttggtggattctgtggcc
aagacgctggacgccggctgcaagccctacatggctcccgagagaatcaacccggagctt
aaccagaagggctacaatgtcaagtccgatgtctggagtctcggcatcaccatgattgag
atggccattctacggtttccgtatgaatcctgggggactccgttccagcagctgaagcag
gtggtggaagagccatctccccagctcccggctgaccgtttctctcctgagttcgtggac
ttcactgcacagtgcttgaggaagaaccccgcggagcgcatgagctacttggagctgatg
gagcacccattcttcacattgcacaaaaccaagaagacggacattgcagccttcgtgaag
gagatcctgggggaggactcatag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (21)   
   KEGG PATHWAY (21)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (11)   
   Pfam (11)   
All databases (43)   

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