KEGG   Vulpes vulpes (red fox): 112935591
Entry
112935591         CDS       T05911                                 
Symbol
DOT1L
Name
(RefSeq) LOW QUALITY PROTEIN: histone-lysine N-methyltransferase, H3 lysine-79 specific
  KO
K11427  [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
Organism
vvp  Vulpes vulpes (red fox)
Pathway
vvp00310  Lysine degradation
vvp01100  Metabolic pathways
vvp05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:vvp00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    112935591 (DOT1L)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    112935591 (DOT1L)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:vvp03036]
    112935591 (DOT1L)
Enzymes [BR:vvp01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.360  [histone H3]-lysine79 N-trimethyltransferase
     112935591 (DOT1L)
Chromosome and associated proteins [BR:vvp03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     112935591 (DOT1L)
   HMT complexes
    Dot1-containing complex
     112935591 (DOT1L)
SSDB
Motif
Pfam: DOT1 HALZ
Other DBs
NCBI-GeneID: 112935591
NCBI-ProteinID: XP_025875137
UniProt: A0A3Q7UPI5
Position
Unknown
AA seq 1731 aa
MPRAGAVRWPCRVPAPCTTGGCKPCPFVFQDKHHDAAHEIIETIRWVCEEIPDLKLAMEN
YVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNH
SVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAAT
NCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSV
IFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELS
PLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPT
KVPESKAAVPADTPMDSGAEEEKAGATTIKKPSPSKARKKKLNKKGRKMAGRKRGRPKKM
STANPERKPKKSQTALDLLHAQAASQTAAPSPQDAYKSPHSPFYQLPPSVQRHPPDQLLL
APTPPALQKLLESFKIQYLQFLAYTKTAQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQ
AQKEEIKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQLQKDNRELRSQSL
QLLKARCEELKLDWSTLSLENLLKEKQALRSQISEKQRHCLELQISIVELEKSQRQQELL
QLKSCVPPDEALSAHLRGKGALGRELEADPSRLHLDLDCSKFSLPHFSSASPELSMNGHA
ANYELCSALSRPSSKQNTPQYLASPLDQEVVPCTPSHSSRSRLEKMSGLALPDYTRLSPA
KLVLRRHLSQDHATSGKPAAGELHPRAEHTKENGLPYQSPGIANGIKLSPQDPRPSSPVA
LQMTGERGSEKGLKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKV
RSTPSPVPQTRESSSTLEKQMGTNTHSAGSKSLASTPAGFYTGSVAVSGALAGSPAPLAP
GAEPSAFDEVSGSGSLFASMGSCSSTPQHPPLLPQSRGSGAASPAHPLCASPRLSSVAQG
PLPDANKGDLPSEAGFSDPEGEAKRRIVFTISAGGSSAKQSPPSKPSPLPTGARGDSSQG
HGSDSRKRGRRKRASAGTPSLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVSNINQPL
EITAISSPESLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEQGSEDEPGSAR
IERKIATISLESKSPPKTLESGGGLAGRKPTPASEPTNSSKWKSTFSPISDLGLAKCADS
PLQAGSTLSQNSLFTFRPPLDDPGSADTKLAAHPRKSFPGALSGAGGLSPSSNPPNGFAF
GGGLAADLSLHSFSDGASLSHKVPEAASLGAPLSFPASRGKEGGATEPGAFVNKRQLDGL
GGPKGREAGELGLPVCGPPDKASLTHSKPTKGRDREPDLKNGHNLFISAATVPPAGLLSG
PGLATVASSAVSAAPSAQTHRPFLGTFTPGPQFALGPMSLQANLGSSVLQSLFSSVPAAA
GLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGVFNHAVPSASAHPFGASFGSGAACRSAT
LSLTPLQAVASAPASSFQAPPPPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAPPPPNAA
LPPAPALLPANSEPVLLQNLASLPANQAFLPASSAASLQPANASLSIKLASLPHKAPRPS
FTVHHQPLPGLALAQAAPVIPQASSTGPSAVWVSLGMPPPYAARLAGVKPR
NT seq 5196 nt   +upstreamnt  +downstreamnt
atgccccgggccggggctgtccgttggccttgccgggtccccgcaccctgcaccactgga
gggtgtaaaccctgtccctttgtctttcaggacaaacaccacgatgctgctcatgaaatc
atcgagaccatccgatgggtctgtgaagagatcccagacctcaagcttgctatggagaat
tacgttttaatcgactacgacaccaaaagcttcgaaagcatgcagaggctctgtgacaaa
tacaaccgtgccatcgacagcatccaccagctgtggaaggggaccactcagcccatgaaa
ctgaacactcggccgtccaacgggctcctgaggcacatcctgcagcaggtgtacaaccac
tcggtgacggaccccgagaagctcaacaactatgagcccttctccccggaggtgtacggg
gagacctcctttgacttggtcgcacagatgatcgacgagatcaagatgaccgaggatgac
ctgtttgtggacctgggcagtggagtgggccaggttgtgctgcaggtcgccgcggccacc
aactgcaaacatcactatggtgtggagaaagctgacatcccagccaagtacgcggagacc
atggaccgagagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacaca
ctggaaagaggcgacttcctctcagaagagtggagagagcggattgccaacacaagtgtt
atatttgtgaataattttgcctttggtcctgaggtggatcaccagctgaaggagcggttt
gcgaacatgaaggaaggcggcagaattgtgtcctcgaagcccttcgcacctctcaacttc
cggataaacagcagaaacttgagtgacatcggcaccatcatgcgcgttgtggagctctcg
cccctgaaaggctcggtgtcctggacggggaagccggtctcctactacctgcacactatc
gaccgcaccatacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggaa
caagaggcagctcggcgccggcagcagcgagagaacaagagcaacacgaccactcccacc
aaggtgcccgagagcaaggctgctgtgcctgccgacacccctatggattctggtgccgag
gaagaaaaggctggggcaaccaccatcaaaaagccgtctccctccaaagcccggaagaag
aagctgaacaagaaggggcggaagatggccggccggaagcgtgggcgtcccaagaagatg
agcactgcgaaccccgagcgtaagcccaagaagagccaaactgcactggacctcctgcat
gcccaggccgcgtctcagacggcagcgccctcgccgcaggatgcgtacaagtcacctcat
agcccgttttatcagctacctcccagtgtgcagcggcacccccctgaccagctgctcctg
gcacccaccccacccgcactgcagaagctgctagaatccttcaagattcagtacttgcag
ttcttggcgtacaccaagaccgcccagtacaaggccagcctgcagcagctgctggaccag
gagaaggagaagaacgcccggttgctaggtgctgcgcagcagctgtttggccactgccag
gcccagaaagaggagatcaagaggctcttccagcagaaactggatgagctgggagtgaag
gcgctgacctacaacgacctgattcaggcacagaaggagatctcggctcataatcagcag
ctgagggaacagacggagcagctgcagaaggacaacagggagctgaggagccagagccta
cagctgctcaaggctcggtgtgaggagctaaagctggactggtccacgctgtccctggag
aacctgctgaaggagaagcaggccctgagaagccagatctccgagaagcagaggcactgc
ctggagctgcagatcagcattgtggagctggaaaagagccagcggcagcaggagctcctg
cagctcaagtcctgtgtgcctccagatgaggccctgtcagcgcacctgcgtgggaagggc
gccctgggccgggagctggaggccgaccccagccgactgcacctcgacctggactgctcc
aagttctctctgccccacttcagcagcgcaagcccagagctctccatgaacggccacgca
gccaactacgagctctgcagcgcgctgagccggccctcatccaagcagaacacgcctcag
tacctggcctccccgctggaccaggaagtcgtaccctgcacccccagccacagcagccgg
tcgaggctcgagaagatgtctggcctggctttgcccgactacaccaggctctccccggcc
aagctggtgctgcggcgtcacctgagccaggaccatgcgaccagcggcaagccagccgcc
ggtgagctgcacccacgagctgagcataccaaggagaacggccttccataccagagccct
ggcatcgcaaacggcatcaagctgagccctcaggaccctcgaccctcgtcccccgtggcc
ttacagatgacaggagagaggggcagtgagaagggcttgaaggagcgtgcttatgccagc
agcggagaggccatcaccagcctgcccgttagcatcccgctcagcactgtgcagcccagt
aagctgcccgtcagcatccctctggccagtgtggtgctgcccagccgcgccgagaaagtg
agaagcacccccagccctgtgccgcagacccgagagtcctcgtccacacttgaaaagcaa
atgggcacaaacacccacagcgctggaagcaaaagccttgcctcaactcctgcaggcttc
tacacgggctcggtggccgtcagtggggccctggcaggcagcccagcgcccctggctcct
ggagcagagcccagcgccttcgacgaggtctctggctcaggaagcctgttcgccagcatg
gggtcctgcagctccaccccgcagcacccgcccctgctgccacagtcccgtggctctggc
gcagcctcacccgcccatccgctctgtgccagtccgcggctcagcagtgtcgcccagggc
ccgctccccgatgccaacaaaggggaccttccgtccgaggcaggcttctcagaccctgag
ggcgaagccaagaggaggattgtctttaccatctcagctggtggcagcagtgccaaacag
tcgcctcccagcaaacccagccctctgcccacgggtgcccgcggggacagcagccagggc
catgggtcggacagccgcaagcggggcaggagaaagcgggcctcggcagggaccccgagc
ctgagctcaggcgtatcacctaagcgtcgagccttgccgtccgttgccggcctcttcacg
cagtcttcagggtccccgctgaacctcaactctatggtcagcaacattaaccagcctttg
gaaatcacggccatctcgtcccccgagagcctgaagagctcccctgtcccttaccaggac
aacgaccagcctcccgttctcaagaaggagaagcccctgagccagaccaatggggcccac
tactccccactgacctcagatgaggagcagggctctgaggacgagccaggcagtgccaga
atcgagagaaaaattgcaacaatttccttagaaagcaaatcccctccaaaaaccttggaa
agcggtggtggcctggccgggaggaagccgacccctgccagtgagcccaccaacagcagc
aagtggaagtccaccttctcgcccatctccgacctcggcctggccaagtgcgccgacagc
ccgctgcaggccggctccaccctgagccagaactccctgttcactttccggcctcccctc
gatgatcccggctctgccgacaccaagctggctgcccaccccaggaaaagctttcccggc
gctctgtcgggggccggtgggctgagcccaagcagcaaccctcccaacggcttcgccttc
ggtgggggcctggccgccgacctcagtttacacagcttcagcgatggtgcttctctctcc
cacaaggtccccgaggcggccagcctgggcgcacccctgagctttcctgcctctcggggc
aaggagggcggtgccacagagcccggcgcctttgtgaacaagaggcagctggacggactg
ggcggcccgaagggcagggaggcgggcgagttgggcctgccagtgtgcgggcccccggac
aaggcctcgctgacgcacagcaagcccaccaagggccgggaccgcgagcccgacctgaag
aatggccacaacctcttcatttctgctgccaccgtgcctcccgctggcctcctcagtggc
cccggcctcgccacggtggcatcctcggcagtcagcgcggccccgtctgcccagactcac
cgccccttcctgggcaccttcacccccgggccgcagttcgccctgggtcccatgtccctg
caggccaacctgggttcgtccgtgctgcagtccttgttcagctccgtgccggctgctgct
ggcctggtgcacgtctcgtccgctgcaaccagactgaccaactcgcacgccatgggcagc
ttttcctcgggggtggcaggcggcgcagttggaggtgtctttaaccacgcggtgccttcc
gcctccgctcatccgtttggagccagtttcggcagcggggctgcgtgtcgcagcgccacg
ctgagcttaaccccgctgcaggcggtggccagcgcccccgcgtcttcctttcaggccccg
cccccgcccnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn
nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnngcaccccctccccctaacgccgcc
ttgcctcctgcccccgcgctgctcccggctaactctgagcccgtgcttctgcagaacctt
gcgtccctcccagctaaccaggctttcttacctgcctcctctgccgcctctctgcagcct
gctaacgcctctctgtccatcaagctcgcttccctcccgcacaaggccccccgcccctcc
ttcacggtgcaccaccagcccctgcccgggctggccctggcccaggccgcgcccgtgatc
ccgcaggccagctccacggggccgtctgccgtgtgggtttcccttggcatgccgcctccg
tatgccgcgcgccttgcgggggttaagccgagataa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (25)   

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