KEGG T01186: XBJ1

Xenorhabdus bovienii SS-2004: XBJ1_3609

Entry

XBJ1_3609         CDS       T01186

Symbol

cysG

Name

(GenBank) multifunctional siroheme synthase: uroporphyrinogen methyltransferase; 1,3-dimethyluroporphyriongen III dehydrogenase; siroheme ferrochelatase

K02302

uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]

Organism

xbo Xenorhabdus bovienii SS-2004

Pathway

xbo00860

Porphyrin metabolism

xbo01100

Metabolic pathways

xbo01110

Biosynthesis of secondary metabolites

xbo01120

Microbial metabolism in diverse environments

xbo01240

Biosynthesis of cofactors

Module

xbo_M00846

Siroheme biosynthesis, glutamyl-tRNA => siroheme

xbo_M00924

Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide

Brite

KEGG Orthology (KO) [BR:xbo00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    XBJ1_3609 (cysG)
Enzymes [BR:xbo01000]
1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     XBJ1_3609 (cysG)
2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     XBJ1_3609 (cysG)
4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     XBJ1_3609 (cysG)

SSDB

Motif

Pfam:

TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M XdhC_C

Other DBs

NCBI-ProteinID:

CBJ82727

UniProt:

D3V4Z8

Position

complement(3501780..3503240)

AA seq 486 aa
MDYLPLFVELKSRPVLLVGGGEVAARKASLLLRAGASLTIVAPELHSELQQRYQKAEFEW
RQGGFRTEYLDGVFLVIAATDDHDLNQHIFAEANARAILVNVVDDQPLCSAIFPSIIDRS
PIMVAISSAGKSPVLAKLLREKLESLLPFHLGIMAEIAGRWRERVKQRLTSIRQRRHFWE
KALNGRFATLVANGQLQQAEAQLDEQLIDEQRANEQLAPAGKQGELALVGAGPGDPGLLT
LKGLQVIQQADVVLYDHLVSADILELVRRDADQICVGKRAGNHSVAQEETNALIIKLARQ
GKKVVRLKGGDPFIFGRGGEELQVAAEAGIPFQVVPGITAAVGASAYAGIPLTHREHSQS
VTFITGHCRENGDELDWPALARGNQTLAIYMGIIKAALISQKLISHGRDANTPVAVIGCG
TRPEQQVLTGTLSELDRLAQKAPSPALLVVGEVAQLHHQIAWFGQQSVDQKQSVAQINRP
AVVDLV

NT seq 1461 nt +upstreamnt +downstreamnt
gtggactatttacccttatttgttgagttaaaatcccgacctgtattgctggttggaggt
ggagaggtagctgctcgtaaggcaagcctgctgctacgtgcgggtgcgtcgctaacaata
gtcgcccctgaattgcattctgagctgcaacaacgctatcaaaaagcggaatttgaatgg
aggcagggtggatttcgaacagaatatcttgatggcgtatttttggttattgcggcaaca
gatgaccacgatttgaaccagcatatttttgctgaggccaatgctcgcgctattttggtc
aatgtagtggatgatcaaccgctttgctcggctattttcccctcaattatcgatcgttct
ccgattatggtggcgatttcatccgcaggaaaatccccggtattggcaaaattgctgcga
gaaaaactggaatccctactgccctttcatcttggcatcatggcagagattgcagggcgc
tggcgtgagcgcgtgaaacagcgtctgacttccatacgccagcggcgtcacttttgggaa
aaagccttgaatgggcgttttgccacattggtagctaatggacaactacagcaggcagaa
gcacaactcgatgaacaattgatcgatgaacaacgagccaacgaacaactcgcgccagcc
ggcaaacagggcgaattggctttagtaggagcagggccgggcgatccgggattgctgacc
ttaaaaggtttacaagtgattcagcaggctgatgttgtgctttatgaccatctggtcagt
gcagatattttggaattggtacgccgcgatgcagatcaaatctgtgttggcaaaagggca
gggaatcactcagtagctcaggaagagactaatgcattaattattaaactagcgcgtcag
ggtaaaaaagtagttcgtctgaaagggggcgatccattcattttcggtcgtggtggagaa
gaattgcaggttgctgctgaagcgggtattccctttcaggtagtacccggtattaccgca
gcggtaggcgcttctgcttatgccggtattccactgacacacagagagcactcccaaagt
gtcacctttattacaggacactgccgtgaaaatggcgatgaactggattggcctgcatta
gcgcggggtaatcaaacattggcaatttacatgggtatcataaaagctgccctgatcagc
caaaaattgatttcacacggacgagatgccaataccccagtagccgtgatcggctgcgga
actcgtccagaacagcaggtactgaccggaaccctatccgaactggatcggttggcacaa
aaagcaccatcgcctgcacttctggtggtgggagaggtggctcaactccaccaccagata
gcatggttcgggcaacagtctgttgatcaaaaacaatctgttgctcaaataaatcgccct
gctgttgttgatctcgtataa

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