KEGG   Xiphophorus couchianus (Monterrey platyfish): 114146596
Entry
114146596         CDS       T05908                                 
Symbol
egfr
Name
(RefSeq) epidermal growth factor receptor isoform X1
  KO
K04361  epidermal growth factor receptor [EC:2.7.10.1]
Organism
xco  Xiphophorus couchianus (Monterrey platyfish)
Pathway
xco04010  MAPK signaling pathway
xco04012  ErbB signaling pathway
xco04020  Calcium signaling pathway
xco04068  FoxO signaling pathway
xco04144  Endocytosis
xco04510  Focal adhesion
xco04520  Adherens junction
xco04540  Gap junction
xco04810  Regulation of actin cytoskeleton
xco04912  GnRH signaling pathway
Brite
KEGG Orthology (KO) [BR:xco00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    114146596 (egfr)
   04012 ErbB signaling pathway
    114146596 (egfr)
   04068 FoxO signaling pathway
    114146596 (egfr)
   04020 Calcium signaling pathway
    114146596 (egfr)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    114146596 (egfr)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    114146596 (egfr)
   04520 Adherens junction
    114146596 (egfr)
   04540 Gap junction
    114146596 (egfr)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    114146596 (egfr)
 09150 Organismal Systems
  09152 Endocrine system
   04912 GnRH signaling pathway
    114146596 (egfr)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:xco01001]
    114146596 (egfr)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:xco04147]
    114146596 (egfr)
Enzymes [BR:xco01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     114146596 (egfr)
Protein kinases [BR:xco01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   114146596 (egfr)
Exosome [BR:xco04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   114146596 (egfr)
  Exosomal proteins of pancreatic cancer cells
   114146596 (egfr)
  Exosomal proteins of bladder cancer cells
   114146596 (egfr)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 ABC1 Kinase-like Haspin_kinase LapA_dom
Other DBs
NCBI-GeneID: 114146596
NCBI-ProteinID: XP_027876628
Position
6:complement(18535347..18578362)
AA seq 1209 aa
MTPHFPYRSFENTMAARFLRWISLTSLLCFGSCVLAEKKVCQGFSNRVNLMDNKEDHYLN
MVKTYSNCTIVLENLEITHVDENRDLSFLKSIEEVSGYVLIALNTVSRIPLENLRIIRGH
SLYEEKFALSVLANIDKNTGQGTTELLLTSLTEILRGGVKFLNNKLCNVETIQWFDIVNA
DTKPSMELQVAGNNPFCNKCHSSCYNGSCWAPGAENCQTLTKLNCAQQCSKRCKGPSPSD
CCNEHCAAGCTGPTAADCLACRDFQDDGVCKDSCPGLMRYDPNLHQLVPNPQGKYNFGAT
CVKNCPHNYVVTDHGACVRTCSGNTYEVEEGGIRKCAKCNGLCPKVCNGLGYGDLTYILS
VNATNIGSFKNCTKITGDITILRTSIHGDPYTKTPKMEPAQLDVFKTVKEITGHLWIQDW
PKSMNSLSPFENLEIIRGRTKRGSRSLVVTLLDIDYLGFRSLKEISDGDVVIIKNHNLCY
MDDSYWKRFFKSGGQTATVNENANATICVLRNKTCDRKCTADGCWGLGPDMCFACRDYSR
GGSCVDFCNILEGEPREAVMNKTCMECDPECLRMNGTATCQAPGPGNCTKCANFQDGLYC
VPRCPQGVPGEGDTLVWKYVDEKRVCQLCHKNCTKGCVGPGPEGCQGERPSGLSIIAAGV
VGGLLAVLIAGLSVFVLLRRRHIKRKRTMRRLLQERALVEPLTPSGQAPNQALLRILKEP
EFKKIKVLGSGAFGTVYKGLWVPEGEDVKIPVAIKVLREATSPKANQEILDEAYVMASVE
HPHVCRLLGICLTSTVQLITQLMPYGCLLDYVKEKKDNIGSQHLLNWCVQIAKGMNYLEE
RHLVHRDLAARNVLVKTPHHVKITDFGLAKLLNADEKEYHADGGKVPIKWMALESILNRT
YTHQSDVWSYGVTVWELMTFGTKPYDGIPASEIAGILEKGERLPQPPICTIDVYMIMVKC
WMIDADSRPHFRELIAEFTKMARDPPRYLVIQGDDRMHLPSPTDTKFYRSLISGGDLDYG
VDAEEYLVPQHSFFSSPSTSYTPLLHSTSINSSIGTSKTRNGLMNGVPSRDGSTVLRYMP
DPTDKFLDQAFLPAPEYMNQNGISNVINYVYQHSGPPRTLLPTISSDDTESEYLNYFKNG
ANGPEYLNELPSSTALPLNSNNTAIGGQNYRPQNSMDNPDYQQDFTPTFKTHTNGHIPAA
ENVEYLGPD
NT seq 3630 nt   +upstreamnt  +downstreamnt
atgacaccgcactttccatacaggagcttcgaaaacaccatggcagcccgttttctgcgg
tggatcagcctcacctctctgctctgctttggctcctgtgttctggcggaaaagaaagtt
tgccagggcttcagcaatcgcgtcaatcttatggacaataaagaggaccactacctgaac
atggtgaagacctacagcaattgtactattgtcctggaaaacctggagattactcacgta
gatgagaaccgtgacctgtccttcctcaagtcaattgaagaagtgagtggctacgttctg
attgccctcaacacagtttctaggattcccctggagaatctgcgcatcattcggggtcac
tccctctatgaggaaaagtttgcactttctgtgcttgccaatattgataaaaatacaggt
cagggaaccaccgagcttcttctgaccagcctaacagaaattctcagaggaggtgtaaag
tttttgaacaacaagctttgtaatgtagaaacaattcagtggtttgatattgtcaatgct
gatactaaacccagcatggaacttcaagtggccggaaacaacccattctgtaacaaatgc
cactcaagttgttacaatggttcatgttgggcacctggtgcagaaaactgtcagaccctg
accaagctgaactgtgcacagcagtgctcaaagaggtgcaaaggaccttcaccaagcgac
tgttgcaatgagcattgtgcagcaggatgcacaggacccacagccgctgactgcctggcc
tgtcgggacttccaggatgacggggtttgtaaggactcctgccctggccttatgcgctat
gatcccaacctacaccagctggtccctaacccccaaggaaagtacaactttggtgccacc
tgcgtgaaaaactgcccacataattatgttgtgaccgatcatggtgcgtgtgtgcggaca
tgcagcggtaacacatatgaagtggaagaaggaggtatcaggaagtgtgccaagtgtaac
ggactgtgcccaaaagtgtgtaatggacttgggtatggagacctgacttacatactatct
gtcaatgccaccaacatcggctcctttaaaaactgcactaaaatcactggtgacattact
atccttagaacatcaattcatggtgatccctataccaaaacgccaaagatggagccagct
cagctggatgtgtttaaaacggttaaggaaattacaggacacctgtggattcaagattgg
ccgaagagcatgaactcgctctcaccttttgaaaatctagaaatcattcgaggaagaaca
aagcgtggtagccgcagcttggttgtgacactgctcgatatcgactaccttggctttcgg
tcactaaaggagatcagcgacggagacgtggtcattatcaaaaatcacaacctttgctac
atggatgacagctactggaaaaggttcttcaaatcaggaggccaaactgcaacagtcaat
gaaaatgcaaatgctaccatttgtgtcctgaggaataagacctgtgacaggaagtgtaca
gcagacggctgctggggcctaggcccggacatgtgtttcgcctgccgtgactacagccgc
ggcgggagttgtgttgacttctgcaacatcctggagggcgagccacgggaggcggtcatg
aataaaacttgcatggagtgtgaccctgagtgtctacgcatgaacgggacagcaacttgt
caggcgccgggtcctggaaactgtacaaagtgtgccaactttcaggatggactgtactgc
gtgccccgttgtccccaaggcgtgcctggagagggtgacaccttggtgtggaaatacgta
gatgagaaacgagtgtgccagctgtgccacaagaactgcaccaaggggtgtgtgggacca
ggtcccgaaggttgccaaggtgaaaggccttcaggtctctccataattgcagctggggtt
gttggtggactgctggcagttctgatcgcaggcctctctgtctttgtgctcctacgccgc
cgccacatcaagagaaagaggacaatgcgcagactgctccaggagagagcgctagttgaa
cctctcactccaagtggacaggcaccaaaccaagctctgctgcggatactgaaggagcca
gagtttaagaaaattaaagtgctgggatcaggagccttcggtacagtttacaagggtctt
tgggtcccagaaggagaggatgtgaagatcccagtggctatcaaggttctgagagaggcc
acatcaccaaaagccaatcaagagatcttggatgaagcctatgtgatggccagtgtggaa
cacccccatgtgtgccgtctgctgggtatctgcctcacctcgacggttcaactcataacc
cagctgatgccgtacggctgcctgctggactacgtcaaagaaaaaaaggacaatattggc
tcccagcacctgctcaactggtgtgttcagatagcaaagggaatgaactacctagaggag
cgccacctagtgcaccgtgacttagcagccagaaacgtcctggtcaagactcctcatcat
gtcaagatcactgactttgggctggccaaactcctcaacgcagatgagaaagaataccat
gcagatggaggaaaggtaccgataaaatggatggctcttgaatcaatcctgaacagaact
tacactcatcagagcgatgtctggagctacggtgtaaccgtctgggaactgatgacgttc
gggaccaaaccatatgatgggataccagccagtgaaatagccggaatcctggagaaagga
gagcgcctccctcaaccaccaatctgtactatagatgtctacatgatcatggtgaaatgt
tggatgattgatgcagacagccggcctcattttcgagaactaatagccgagttcacgaag
atggctcgagatccaccccgctatcttgtcattcagggcgatgaccgcatgcatctgccg
agtccaacggacaccaaattttaccgcagcctgatcagtgggggggacctggattatggt
gtagatgcagaagaatacttggtgccacagcacagcttcttcagcagcccaagcacctcc
tacaccccgttgcttcactccacgagcattaatagcagcatagggaccagcaaaaccaga
aatggcttaatgaatggagtcccaagcagagacggaagtacggttctccgatatatgcct
gaccccacagacaaattcttggaccaggccttcctgccggctccagaatacatgaaccag
aacggaatctccaatgtgataaattacgtctaccaacattcaggtccacctcgcaccctt
cttccaaccatctcttcagatgatacagagtcagagtacctgaactactttaagaacgga
gccaacggacctgaatacctcaatgagctcccatcctccaccgccctacccctcaactct
aacaacacggccatcggcggtcaaaactacaggcctcaaaacagcatggacaatccagac
taccaacaggatttcactcccactttcaagacacacacaaatggacacataccagcagca
gagaacgtagagtaccttggtccagactga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (10)   
   Pfam (10)   
All databases (33)   

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