KEGG   Xenopus laevis (African clawed frog): 447268
Entry
447268            CDS       T01010                                 
Symbol
braf.L, B-Raf, b-raf1, braf1, rafb1
Name
(RefSeq) B-Raf proto-oncogene, serine/threonine kinase L homeolog
  KO
K04365  B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
Organism
xla  Xenopus laevis (African clawed frog)
Pathway
xla04010  MAPK signaling pathway
xla04012  ErbB signaling pathway
xla04068  FoxO signaling pathway
xla04150  mTOR signaling pathway
xla04270  Vascular smooth muscle contraction
xla04510  Focal adhesion
xla04810  Regulation of actin cytoskeleton
xla04910  Insulin signaling pathway
xla04914  Progesterone-mediated oocyte maturation
Brite
KEGG Orthology (KO) [BR:xla00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    447268 (braf.L)
   04012 ErbB signaling pathway
    447268 (braf.L)
   04068 FoxO signaling pathway
    447268 (braf.L)
   04150 mTOR signaling pathway
    447268 (braf.L)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    447268 (braf.L)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    447268 (braf.L)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    447268 (braf.L)
   04914 Progesterone-mediated oocyte maturation
    447268 (braf.L)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    447268 (braf.L)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:xla01001]
    447268 (braf.L)
Enzymes [BR:xla01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     447268 (braf.L)
Protein kinases [BR:xla01001]
 Serine/threonine kinases: TKL group
  RAF family [OT]
   447268 (braf.L)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase RBD C1_1 Kinase-like zf-RING-like ABC1 C1_2 Pkinase_fungal Kdo
Other DBs
NCBI-GeneID: 447268
NCBI-ProteinID: NP_001087444
Xenbase: XB-GENE-17346700
UniProt: Q4F9K6
Position
3L:5857891..5881304
AA seq 802 aa
MAALSGGSAEGPSLLNGDLLESETGGLGGAGEMSVSGGYPEEVWNIKQMIKLTQEHIEAL
LDKFGGEHNPPSIYLEAYEEYTSKLDLLQQREQQLLESMGNGSDSSSLSSELTISSVPSN
LSLAPSTLSALHTPSDPSRINPRSPQKPIVRVFLPNKQRTVVPARSGVTVRDSLKKALMM
RGLIPECCAVYRVQDGEKKPIGWDTDISWITGEELHVEVLENVPLTTHNFVRKTFFTLAF
CDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDRLDLLFVSKFFEHHPISQEEAPF
EEFVPAVESLTPPPPPDATGPPSLPSASPSKSIPIPQPFRPDEDHRNQFGQRDRSSSAPN
VHINTIEPVNIDDLIQDPGLQRIEGAPSVQPTRCHRKYHSRDPSPLLHTLPSEIVFDFES
DPVCRGSTPGLSATPPASLPGSLANVKALQKSPGQQRERKSSSSSMEDRSRMKTLGRRDS
SDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKILNVTAPTPQQLQAFKNEVGVLR
KTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDY
LHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIR
MQDNNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDFSKVRSNCP
KAMKRLIADCLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLY
TCASPKTPIQGGAYGGFVIGAL
NT seq 2409 nt   +upstreamnt  +downstreamnt
atggcggcgctaagtgggggatcagcagaggggccctcgttgcttaacggggacctgctg
gagtccgagaccgggggactgggcggagccggcgagatgtctgtgtccggggggtatccg
gaagaggtctggaatatcaaacaaatgataaagttaacacaagagcacatagaagccctg
ttggacaagtttggaggcgagcacaaccccccatcaatatatctagaggcctatgaagaa
tataccagcaaactggatctattgcagcagagggagcagcagttactggagtctatgggc
aatggaagcgactcctcttctttgtcttcagagctgacgatttcctcagtcccgtcgaat
ctatccttggcaccttcaactctctcagccctgcacaccccctctgatccctcccgcatc
aaccccagatctccccagaaaccgatcgttcgagtcttccttcccaacaagcagcgcact
gtggtaccagcaaggagtggtgtgacagtgcgagacagcttaaagaaagccctgatgatg
cgaggcttgatcccagaatgctgtgctgtctacagggtgcaggatggggagaagaagccg
attggctgggacacagatataagctggatcaccggagaagagttacacgtggaagtcttg
gagaatgtgccactcacaacccataactttgtacggaaaaccttcttcacactcgctttc
tgtgacttctgccggaagctgctattccagggctttcgctgccagacgtgtgggtacaag
ttccaccagcgctgcagcacggaggtgcctctcatgtgtgttaactacgaccgcctagat
ttgctgtttgtctccaagttctttgagcaccacccgatatctcaggaggaagctcctttt
gaagagtttgtcccagccgttgagtcgttgactcctccgccccctccagatgccacaggc
cctcccagtctaccaagtgcttctccttctaagtccatcccgataccccagccgttccga
cccgacgaggaccaccggaaccagtttggccagcgggatcgatcgtcctcggcgccgaac
gtgcacataaacaccatcgaaccggtcaatatagatgacttgattcaagacccgggtctc
cagcgcatcgagggagccccctcagtccagccgacgcgctgccatcggaaataccattca
cgggatcccagcccactccttcatactctccccagtgaaatagtctttgattttgaatct
gatcccgtttgcagaggttcaactcctggcttatcggcgaccccacctgcctccctcccc
ggctccctcgccaacgtcaaggccctacagaaatccccaggccagcaaagagagcgcaag
tcctcctcgtcctcaatggaagacaggagtcgaatgaaaacgcttggacgtcgcgactcc
agtgacgactgggagattcctgatgggcaaatcacagttgggcagagaataggttctgga
tcttttgggacagtatataagggaaagtggcatggggacgtagcggtgaaaatattgaat
gtaacggctccaacgcctcagcagctacaggcctttaaaaatgaagttggagtcctccga
aaaacacgacacgtgaacatcctgcttttcatgggctactccacgaagccccaactggca
atagtgacccagtggtgcgagggctccagtctctatcaccatctgcacatcatcgagacc
aaatttgagatgattaaacttatcgacattgcacggcagacggcacagggcatggactat
ttgcacgcaaagtccatcattcacagagacctgaagagcaataatatattccttcatgaa
gacctcacggtgaagatcggtgactttggtttggcgacggtgaagtcccggtggagtggc
tctcatcagtttgagcagttatccggctccattctgtggatggctccggaggtcattcgg
atgcaagataacaacccgtacagctttcagtccgacgtctacgcctttggcattgttctg
tacgaattaatgacagggcagttgccctactcgaatatcaacaacagagaccagatcata
tttatggtcggcagaggctacttatctccagacttcagcaaagttaggagtaattgtccc
aaagcaatgaagcggttaatagcagactgcctgaagaagaagagagatgaacggccccta
ttcccacagattctcgcctccattgaactgctggcccggtcattgccaaaaatccaccgc
agtgcgtctgagccgtccttgaaccgggccggattccagacagaagacttcagtctgtac
acgtgtgcttctcccaaaactcctatccagggcggagcttatggtgggtttgttatcgga
gccctgtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (9)   
   KEGG PATHWAY (9)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   XENBASE (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (9)   
   RefSeq(nuc) (3)   
   GenBank (3)   
   EMBL (3)   
Protein domain (10)   
   Pfam (10)   
All databases (57)   

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