KEGG   Xenopus tropicalis (western clawed frog): 100170194Help
Entry
100170194         CDS       T01011                                 

Gene name
mapk8, jnk, jnk1, jnk1a2, jnk21b1/2, prkm8, sapk1
Definition
(RefSeq) mitogen-activated protein kinase 8
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
xtr  Xenopus tropicalis (western clawed frog)
Pathway
xtr04010  MAPK signaling pathway
xtr04012  ErbB signaling pathway
xtr04068  FoxO signaling pathway
xtr04137  Mitophagy - animal
xtr04140  Autophagy - animal
xtr04141  Protein processing in endoplasmic reticulum
xtr04210  Apoptosis
xtr04217  Necroptosis
xtr04310  Wnt signaling pathway
xtr04510  Focal adhesion
xtr04530  Tight junction
xtr04620  Toll-like receptor signaling pathway
xtr04621  NOD-like receptor signaling pathway
xtr04622  RIG-I-like receptor signaling pathway
xtr04625  C-type lectin receptor signaling pathway
xtr04910  Insulin signaling pathway
xtr04912  GnRH signaling pathway
xtr04914  Progesterone-mediated oocyte maturation
xtr04920  Adipocytokine signaling pathway
xtr04933  AGE-RAGE signaling pathway in diabetic complications
xtr05132  Salmonella infection
xtr05168  Herpes simplex infection
Module
xtr_M00688  MAPK (JNK) signaling
Brite
KEGG Orthology (KO) [BR:xtr00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100170194 (mapk8)
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    100170194 (mapk8)
   04012 ErbB signaling pathway
    100170194 (mapk8)
   04310 Wnt signaling pathway
    100170194 (mapk8)
   04068 FoxO signaling pathway
    100170194 (mapk8)
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    100170194 (mapk8)
   04137 Mitophagy - animal
    100170194 (mapk8)
  Cell growth and death
   04210 Apoptosis
    100170194 (mapk8)
   04217 Necroptosis
    100170194 (mapk8)
  Cellular community - eukaryotes
   04510 Focal adhesion
    100170194 (mapk8)
   04530 Tight junction
    100170194 (mapk8)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    100170194 (mapk8)
   04621 NOD-like receptor signaling pathway
    100170194 (mapk8)
   04622 RIG-I-like receptor signaling pathway
    100170194 (mapk8)
   04625 C-type lectin receptor signaling pathway
    100170194 (mapk8)
  Endocrine system
   04910 Insulin signaling pathway
    100170194 (mapk8)
   04920 Adipocytokine signaling pathway
    100170194 (mapk8)
   04912 GnRH signaling pathway
    100170194 (mapk8)
   04914 Progesterone-mediated oocyte maturation
    100170194 (mapk8)
 Human Diseases
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    100170194 (mapk8)
  Infectious diseases
   05132 Salmonella infection
    100170194 (mapk8)
   05168 Herpes simplex infection
    100170194 (mapk8)
Enzymes [BR:xtr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100170194 (mapk8)
Protein kinases [BR:xtr01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   100170194 (mapk8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr Kdo Kinase-like APH RIO1 FTA2
Motif
Other DBs
NCBI-GeneID: 100170194
NCBI-ProteinID: NP_001123415
Xenbase: XB-GENE-1217556
UniProt: B3DL24
Position
7
AA seq 381 aa AA seqDB search
MSRSKRDSNFSVFEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLERHVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDLYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCILGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPLEADAPPPKIPDKQLDEREHTIEEWKELIYKEV
LDWEDSSRNRRVEQHQHINDC
NT seq 1146 nt NT seq  +upstreamnt  +downstreamnt
atgagccgaagcaagcgtgacagcaacttctctgtctttgagataggagattccactttt
actgttctcaagcgataccaaaatctgaagcctattggatctggagcacagggaatagta
tgtgctgcctatgatgcagttctggagagacatgttgccatcaaaaaactgagccggcca
ttccagaatcaaacccatgccaagagagcttatcgagaacttgtgcttatgaaatgtgtc
aaccacaagaatataattggacttctgaatgtctttactccccagaagtcattagaagag
tttcaggacctgtacattgttatggagcttatggatgccaacctgtgccaggtgatacag
atggaattggaccatgaacgcatgtcctacctgctataccagatgttgtgtggcatcaaa
cacctacattctgctgggatcatccacagggatctaaagccaagtaacatcgtagttaaa
tcggactgcacgcttaagattcttgattttgggcttgcacggacagcaggaaccagtttt
atgatgacaccctatgttgtgactcgttactatagagctccagaagtcatcctgggcatg
ggatataaagaaaatgttgacatttggtcagtgggttgcatcttgggagagatgatcaaa
ggtggtgtgttattccccggcacagaccatatcgaccagtggaataaagtaattgaacag
ttggggacaccatgtccagagtttatgaaaaaattacagccaactgtgaggacatatgta
gaaaatagacccaaatacgctgggtacagctttgagaaactctttcctgatgttttattc
cctgcagactctgagcacaacaaattgaaagcaagccaagccagagatctgctgtcaaaa
atgctagtaatagatgcatccaagagaatttctgtagatgaagctttgcagcatccttat
atcaatgtttggtatgaccccctggaagctgatgcaccaccaccaaagatcccagacaaa
caactggatgagagagaacataccatagaagaatggaaagagctcatctacaaggaggtt
ttggactgggaggacagtagcaggaatcggcgggtggaacagcaccaacatataaatgat
tgctga

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