KEGG   Xenopus tropicalis (tropical clawed frog): 100492965
Entry
100492965         CDS       T01011                                 
Symbol
egfr
Name
(RefSeq) epidermal growth factor receptor
  KO
K04361  epidermal growth factor receptor [EC:2.7.10.1]
Organism
xtr  Xenopus tropicalis (tropical clawed frog)
Pathway
xtr04010  MAPK signaling pathway
xtr04012  ErbB signaling pathway
xtr04020  Calcium signaling pathway
xtr04068  FoxO signaling pathway
xtr04144  Endocytosis
xtr04510  Focal adhesion
xtr04520  Adherens junction
xtr04540  Gap junction
xtr04810  Regulation of actin cytoskeleton
xtr04912  GnRH signaling pathway
Brite
KEGG Orthology (KO) [BR:xtr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100492965 (egfr)
   04012 ErbB signaling pathway
    100492965 (egfr)
   04068 FoxO signaling pathway
    100492965 (egfr)
   04020 Calcium signaling pathway
    100492965 (egfr)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100492965 (egfr)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100492965 (egfr)
   04520 Adherens junction
    100492965 (egfr)
   04540 Gap junction
    100492965 (egfr)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    100492965 (egfr)
 09150 Organismal Systems
  09152 Endocrine system
   04912 GnRH signaling pathway
    100492965 (egfr)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:xtr01001]
    100492965 (egfr)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:xtr04147]
    100492965 (egfr)
Enzymes [BR:xtr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100492965 (egfr)
Protein kinases [BR:xtr01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   100492965 (egfr)
Exosome [BR:xtr04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   100492965 (egfr)
  Exosomal proteins of pancreatic cancer cells
   100492965 (egfr)
  Exosomal proteins of bladder cancer cells
   100492965 (egfr)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 Kinase-like DUF1786 TNFR_16_TM APH
Other DBs
NCBI-GeneID: 100492965
NCBI-ProteinID: XP_002939960
Xenbase: XB-GENE-6067152
UniProt: F6UFM4
Position
6:56745176..56895057
AA seq 1210 aa
MGSFSRSVGLYICVFFVSQSCFSLEEKKVCLGNNNRLNQLGNTDEHYASLKRMYDGCEIV
LGNLEITYLDRLNDTSFLRNIQEVGGYVLIAINSVRSIHLENLQIVRGNMLYKSTYALAI
VSNESLNTTNALEELHMGRLTEILNGGVLISKNRKLCYLNTIQWNDIVHTDNPINKISVD
KSFSPQCPKCDAESCNGSCWGPGQGNCQKLTKLTCAQQCSGRCRGPLPSDCCHSQCASGC
TGPRENNCLACRKFRDGETCKEGCPQLQIYNPATYQMDLNPDGKYSFGASCVKKCPHNYV
VTDHGSCVRTCNSDSQEVEENGIRICKKCDGSCNKDKVCDGINMGKLKSVLSVNASNIDL
FQNCTKVNGDVAILHVAGYGDPFTNTSKLDPAKLSVFKSVREITGSLLIQWWPDNYTDLS
VFENLETIRGRTKQHGIYSLAIVKRSITSLGLRSLKEVSDGDVIIKTNKNLCFVNTINFT
NIFRIPKQARIIEDNKSPEQCESEGNVCDPLCSEEGCWGPGPFQCVSCRKYMRGRECVEN
CNFLSGEPREYTEDGKCFACNAECLQLNETQTCSGPGADECFKCGHNSDGPFCVKTCPAG
IQGENSTLIWKYPDETGACQLCHPECKLGCVGHGLDGCPLPWSSHSVAAGVVGGILGAVV
IGLVAFFFIRRSRINRKRTLRRILQERELVEPVTPSGEAPNQALLRILKETEFKKIKVLG
SGAFGTVYQGLWIPEGEGIKIPVAIKELREATSPKANKEILDEAYVMASVENPYVCRLLG
ICLTSTVQLITQLMPFGCLLDYVRDNKDNIGSQHLLNWCVQIAKGMNYLEERRLVHRDLA
ARNVLVKGPQHVKITDFGLAKLLGADEKAYHAEGGKVPIKWMALESILHRTYTHQSDVWS
YGVTVWELMTFGLKPYDGIPASEISNILEKGERLPQPPICTIDVYMIMVKCWMIDAESRP
KFRELSAEFTKMARDPTRYLVIQGDDRMHLPSPVESKIHPALVQEGLGDIVDAEEYLLPH
QGFFTSPSNSRTPLLSTMSSTSNNSPVICTMRNGGPPVREDSFVQRYSTDPTVILEDSID
DEFLPVPEYVNQMVPKPIVETQTNAVYQNLVPLGNTVSPKENLYQNSHSNGLNNPEYLNT
GHTLVPKTDFDYSSIWDQKANLQINLDNPDYQQDFFPKEPKTNGHFKIPAAQNPEYLGLA
PVSDYIEASA
NT seq 3633 nt   +upstreamnt  +downstreamnt
atggggtcttttagccggagtgtgggattatatatctgcgtcttcttcgtcagtcagtcc
tgcttttctctggaagaaaagaaagtctgcctgggcaataacaacagattaaatcagctg
ggtaacacagacgaacactatgccagccttaaaaggatgtatgatggttgtgaaattgtg
cttggtaatctggaaatcacttatttagaccgcctgaacgatacctccttcctgcggaac
atacaagaagtaggaggttatgtgctcatagcaatcaactctgttagatccattcatctt
gaaaaccttcaaattgttcgtgggaatatgttgtacaaaagcacatatgctctagctata
gtgagtaatgaatcactgaataccactaatgctttggaggaactgcatatgggacgtttg
acagaaattcttaatggcggagtccttatttcaaaaaatcggaaactttgctacttgaat
accatccagtggaatgatattgtgcatacagacaatcccatcaataaaatatctgtggat
aaaagcttttctccccagtgtcctaaatgtgatgcagaaagctgcaatggatcgtgctgg
ggacctggacaaggaaactgtcagaaattaacaaagctcacctgtgcccagcagtgttcc
ggtcgttgcagaggtccactgccaagtgattgctgccacagccaatgtgcttctggctgt
acagggccaagggaaaataactgcttggcttgccgtaagtttcgagatggtgagacatgc
aaagaaggctgccctcagctgcagatatataatcctgcaacataccaaatggatctaaat
cctgatggaaagtacagttttggagcttcatgtgtgaaaaagtgcccacataactatgtt
gtgacagatcatggatcatgtgttcgaacttgcaactcagattcccaagaagtagaggag
aatggtatccgaatatgtaaaaagtgtgatgggtcatgtaataaagataaggtttgtgat
ggaatcaacatgggaaagctgaaaagtgtcttgtcagtaaacgcctcaaatatagattta
ttccagaactgtaccaaagtaaatggagatgtagccattttacatgtggcaggatatggt
gacccttttaccaacactagtaaactggatcctgcaaagttatctgtatttaaatctgtc
cgagaaataacaggttccttattgattcagtggtggccagataattacacagacctgagt
gtgtttgaaaatctcgagactatccgaggcagaacaaagcagcatggcatttattctctt
gctattgtgaaaagatccataacttccttgggtctacgatcgctcaaagaagtgagtgat
ggagatgttatcattaaaacaaacaaaaatctctgctttgttaacaccatcaactttaca
aacatctttagaataccgaaacaggcaaggataattgaagacaacaaaagtcctgagcag
tgtgaaagtgaaggcaatgtttgtgatcctttgtgctctgaggagggatgttggggacct
gggccttttcaatgtgtttcctgccgtaaatatatgcgtggaagggaatgtgtagaaaac
tgcaactttcttagtggggagccacgagaatacacagaagatggcaagtgctttgcctgt
aacgcagagtgtttacagctgaatgaaacccaaacttgctcgggtcctggtgcagatgaa
tgttttaaatgtggtcacaatagtgatggtccattctgtgtcaagacttgcccagctgga
atccaaggagaaaatagcactttaatttggaagtatcctgatgaaacaggagcatgtcag
ctctgtcatccagaatgcaaactgggatgtgtgggacatggcctagatggatgccctctt
ccttggtccagccactctgttgctgcaggtgttgttggaggcattcttggagctgtcgtg
attggacttgttgctttcttctttattagaaggagtcgaatcaataggaaacgaacccta
cgtaggatacttcaagaaagagagctggttgaacctgtcacccccagtggagaggcacca
aatcaagctcttctccggatcttaaaggagacagagttcaagaaaataaaagttcttggc
tctggggcgtttgggacagtttaccaggggctatggattcctgagggggagggcatcaag
atcccagttgccattaaggagttgcgagaagccacgtcccctaaagccaacaaagaaatt
ctagatgaagcatacgtcatggccagcgtggagaatccctatgtttgccgtttgctagga
atctgcctgacctccactgtccagctgatcacccagttaatgccatttggttgcctcctc
gactatgttcgagataacaaagacaacattgggtcacaacatcttctcaactggtgtgtg
cagattgccaagggaatgaattatcttgaagaaagacgtttggtgcatcgtgatttagct
gccaggaatgttctagttaaaggcccacagcatgtcaaaatcacagattttgggctagca
aagcttctgggagcagatgagaaagcgtatcatgcagaagggggcaaagtgcctatcaag
tggatggcattagagtccatcttgcacagaacctacacccatcaaagtgatgtttggagt
tatggggtcacagtttgggaattaatgacattcggtttgaagccctatgatggaattcca
gccagtgaaatctcaaatattttagaaaaaggggagcgtcttccacagcctccaatctgc
accattgatgtctatatgattatggtgaaatgctggatgattgatgcagagagtcgccca
aagttccgggaactgagcgctgaatttaccaaaatggctcgtgacccaacccgctacttg
gtcatacagggggatgatagaatgcatttgcctagtcctgttgaatccaagatccatcct
gcattggttcaagagggtctgggtgacattgttgatgctgaagagtatctgttgccacat
caaggattcttcacaagtccctctaattcaagaacacctttactgagcactatgagttct
actagcaacaactcacctgtcatctgtaccatgcgaaatgggggaccacctgttagagaa
gacagctttgtacaaagatacagcacagatccaacagtcattttggaagacagcattgat
gatgagttcctgcctgtgccagaatatgtgaatcagatggttccaaaaccaattgtggag
acacagacaaatgcagtatatcaaaatttggttccactggggaatactgtgtctcctaaa
gagaacctttaccagaattctcacagcaatggccttaataacccagagtatctgaacaca
ggccatacccttgtacccaaaactgactttgactattcctccatctgggaccaaaaggct
aaccttcagattaacctggataaccctgactatcaacaggacttctttccaaaagaacct
aaaaccaatggacattttaaaattcctgcagcgcaaaaccctgaatacttggggttggca
cctgtgagcgattatattgaagcttcagcatga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   XENBASE (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (10)   
   Pfam (10)   
All databases (34)   

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