KEGG   Xenopus tropicalis (tropical clawed frog): 549871
Entry
549871            CDS       T01011                                 
Symbol
raf1
Name
(RefSeq) RAF proto-oncogene serine/threonine-protein kinase
  KO
K04366  RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
Organism
xtr  Xenopus tropicalis (tropical clawed frog)
Pathway
xtr04010  MAPK signaling pathway
xtr04012  ErbB signaling pathway
xtr04068  FoxO signaling pathway
xtr04140  Autophagy - animal
xtr04150  mTOR signaling pathway
xtr04210  Apoptosis
xtr04218  Cellular senescence
xtr04270  Vascular smooth muscle contraction
xtr04370  VEGF signaling pathway
xtr04371  Apelin signaling pathway
xtr04510  Focal adhesion
xtr04540  Gap junction
xtr04625  C-type lectin receptor signaling pathway
xtr04810  Regulation of actin cytoskeleton
xtr04910  Insulin signaling pathway
xtr04912  GnRH signaling pathway
xtr04914  Progesterone-mediated oocyte maturation
xtr04916  Melanogenesis
xtr05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:xtr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    549871 (raf1)
   04012 ErbB signaling pathway
    549871 (raf1)
   04370 VEGF signaling pathway
    549871 (raf1)
   04371 Apelin signaling pathway
    549871 (raf1)
   04068 FoxO signaling pathway
    549871 (raf1)
   04150 mTOR signaling pathway
    549871 (raf1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    549871 (raf1)
  09143 Cell growth and death
   04210 Apoptosis
    549871 (raf1)
   04218 Cellular senescence
    549871 (raf1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    549871 (raf1)
   04540 Gap junction
    549871 (raf1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    549871 (raf1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    549871 (raf1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    549871 (raf1)
   04912 GnRH signaling pathway
    549871 (raf1)
   04914 Progesterone-mediated oocyte maturation
    549871 (raf1)
   04916 Melanogenesis
    549871 (raf1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    549871 (raf1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    549871 (raf1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:xtr01001]
    549871 (raf1)
Enzymes [BR:xtr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     549871 (raf1)
Protein kinases [BR:xtr01001]
 Serine/threonine kinases: TKL group
  RAF family [OT]
   549871 (raf1)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase RBD C1_1 Kinase-like ABC1 zf-RING-like Pkinase_fungal C1_2
Other DBs
NCBI-GeneID: 549871
NCBI-ProteinID: NP_001017117
Xenbase: XB-GENE-6053330
UniProt: Q28GW9
Position
4:153431523..153473403
AA seq 638 aa
MEHIQGAWKTISNGFSFKDSVFDGSSCMSPTIGHQFGYQRRASDDGKLSDTSKTGSTMRV
YLPNKQRTVVNVRSGMSLHDCLMKALKVRGLQPECCAVFRLIQDPKGKLRLDWNTDAMSL
VGAELQVDFLDHVPLTTHNFVRKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVP
TMCVDWSNIRQLLLFPNPNNMEGGSHTLPSLTVRRMRESVRIPISSQQRYSTPHPFSFST
PSAPSECSLSQRQRSTSTPNVHMVSTTMAVDSRLIEDAVRSHSDSGSPNNLSPTGWSNTK
TPAPTHREKAASSSGQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWH
GDVAVKILKVTNPTPEQLQAFRNEVAVLRKTRHVNILLFMGYMTKENLAIVTQWCEGSSL
YKHLHVLETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGL
ATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDNNPFSFQSDVYSYGIVLFELMTGELPYS
HIRDRDQIIFLVGRGGTVPDLSKLYKNCPKAMKRLVADCIKKMREERPLFPQILSSIELL
QHSLPKINRSASEPSLHRAAHTEDINSCTLTSTRLAVF
NT seq 1917 nt   +upstreamnt  +downstreamnt
atggagcacatacaaggtgcctggaagaccatcagcaatggctttagctttaaagactct
gtgtttgacggaagcagctgcatgtcccccaccattgggcatcagtttggctaccagcgg
cgggcgtcggatgatggcaagctcagcgatacctccaagactggcagcaccatgcgagtg
tacctacccaacaagcagagaaccgtggtcaatgtgcggagtgggatgagtttgcacgac
tgtctcatgaaagctctgaaggttcgagggctccaacccgaatgctgcgcagtcttccgg
ctgattcaggatccaaaggggaagttgcgcttggattggaacacggacgccatgtcgcta
gtcggagcggagctgcaggtggattttctcgatcacgtgccactcacgacacataacttc
gtgcggaaaacatttttaaaactggcattttgcgatatctgtcagaagtttctattaaac
ggctttcgctgccagacgtgtggctacaagttccacgagcactgcagtaccaaggtgccc
accatgtgcgtggactggagcaacatccggcagctgctattattccccaatccaaacaac
atggaagggggcagccacacgttaccctctctgacagtgaggcgaatgcgagaatctgtg
cggattccaatcagctcccaacagagatattcaactcctcaccccttctccttcagcacc
cccagcgctccttctgagtgctccctctcccagagacagaggtccacttccacgcctaat
gtgcatatggtcagtaccacaatggccgtggacagccgccttattgaggatgcggtgcgg
agtcacagcgattcagggagccccaataatctgagtcctacggggtggtccaacaccaaa
acgccggcccccacacaccgagagaaggcagcgtcatccagtgggcaggagaagaacaaa
atacgcccccgtgggcagagagactccagttattactgggagatagaggccagtgaggtg
atgctctccacaaggattggatcgggctccttcggaacagtgtacaaagggaaatggcat
ggggacgtggcagtgaaaatcctgaaggtgaccaatccaacgccagagcagctccaggca
ttcaggaatgaagttgctgtacttaggaaaacgcggcacgttaacattctgcttttcatg
ggctacatgaccaaggagaatctggccatcgtcacgcaatggtgtgaggggagcagcctg
tacaaacatctccatgtcctcgagaccaaattccagatgttccagctcatcgacatcgcc
aggcaaacggcacaagggatggattacctccatgcaaagaatattatccaccgggacatg
aaatccaacaatatctttctccatgaggggttaaccgtgaaaatcggagactttggattg
gccacggtaaagagcaggtggagcggttcccagcaggtggagcaaccgacaggctccata
ctgtggatggccccagaagtgatccgcatgcaggacaataaccccttcagcttccagtcg
gacgtctattcctatgggatcgtgctgtttgagcttatgaccggggagctgccctactcc
cacattagggacagggaccagataatatttctggttggacgaggagggacggtccccgac
ctgagtaagctctacaagaactgccccaaggcaatgaagcgtctcgtggccgattgtatc
aaaaaaatgcgggaggagcgccccctattccctcagatcctttcatctattgagctgtta
caacactcgttacccaaaatcaatcgcagcgcttcggagccgtcgttacaccgcgccgca
cacacagaggacatcaattcctgcacactgacttccacccggctggcagttttctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (19)   
   KEGG PATHWAY (19)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   XENBASE (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (6)   
   RefSeq(nuc) (2)   
   GenBank (2)   
   EMBL (2)   
Protein domain (9)   
   Pfam (9)   
All databases (47)   

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