KEGG   Yokenella regensburgei: HEC60_24120
Entry
HEC60_24120       CDS       T06519                                 
Name
(GenBank) trimethoprim-resistant dihydrofolate reductase DfrA14
  KO
K18589  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Organism
yre  Yokenella regensburgei
Pathway
yre00670  One carbon pool by folate
yre00790  Folate biosynthesis
yre01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:yre00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    HEC60_24120
   00670 One carbon pool by folate
    HEC60_24120
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes [BR:yre01504]
    HEC60_24120
Enzymes [BR:yre01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     HEC60_24120
Antimicrobial resistance genes [BR:yre01504]
 Gene variants
  Trimethoprim resistance genes
   Dihydrofolate reductases
    HEC60_24120
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-ProteinID: QIU92434
UniProt: A0A6H0KGM9
Position
pYRW13-125:complement(22592..23065)
AA seq 157 aa
MKVSLMAAKAKNGVIGCGPDIPWSAKGEQLLFKALTYNQWLLVGRKTFESMGALPNRKYA
VVTRSGWTSNDDNVVVFQSIEEAMDRLAEFTGHVIVSGGGEIYRETLPMASTLHLSTIDI
EPEGDVFFPSIPNTFEVVFEQHFTSNINYCYQIWKKG
NT seq 474 nt   +upstreamnt  +downstreamnt
ttgaaagtatcattgatggctgcgaaagcgaaaaacggcgtgattggttgcggtccagac
ataccctggtccgcgaaaggggagcagctactttttaaagcattgacctacaatcagtgg
cttctggtgggtcgcaagacgtttgaatctatgggcgcactccccaataggaaatacgcg
gtcgttacccgctcaggttggacatcaaatgatgacaatgtagttgtatttcagtcaatc
gaagaggccatggacaggctagctgaattcaccggtcacgttatagtgtctggtggcgga
gaaatttaccgagaaacattacccatggcctctacgctccacttatcgacgatcgacatc
gagccagagggggatgttttcttcccgagtattccaaataccttcgaagttgtttttgag
caacactttacttcaaacattaactattgctatcaaatttggaaaaagggttaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (1)   
   Pfam (1)   
All databases (26)   

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