KEGG   ENZYME: 1.1.1.373
Entry
EC 1.1.1.373                Enzyme                                 
Name
sulfolactaldehyde 3-reductase;
yihU (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
(2S)-2,3-dihydroxypropane-1-sulfonate:NAD+ 3-oxidoreductase
Reaction(IUBMB)
(2S)-2,3-dihydroxypropane-1-sulfonate + NAD+ = (2S)-3-sulfolactaldehyde + NADH + H+ [RN:R10719]
Reaction(KEGG)
R10719
Substrate
(2S)-2,3-dihydroxypropane-1-sulfonate [CPD:C22383];
NAD+ [CPD:C00003]
Product
(2S)-3-sulfolactaldehyde [CPD:C21181];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
The enzyme, characterized from the bacterium Escherichia coli, is involved in the degradation pathway of sulfoquinovose, the polar headgroup of sulfolipids found in the photosynthetic membranes of all higher plants, mosses, ferns, algae, and most photosynthetic bacteria, as well as the surface layer of some archaea.
History
EC 1.1.1.373 created 2014
Orthology
K08318  4-hydroxybutyrate dehydrogenase / sulfolactaldehyde 3-reductase
Genes
ECOb3882(yihU)
ECJJW3853(yihU)
ECDECDH10B_4072(yihU)
EBWBWG_3552(yihU)
ECOKECMDS42_3321(yihU)
ECEZ5420(yihU)
ECSECs_4805(yihU)
ECFECH74115_5329
ETWECSP_4938(yihU)
ELXCDCO157_4544
EOIECO111_4702(yihU)
EOJECO26_4708(yihU)
EOHECO103_4289(yihU)
ESLO3K_24495
ESOO3O_00840
ESMO3M_24415
ECKEC55989_4353
ECGE2348C_4180
EOKG2583_4683(yihU)
ELRECO55CA74_22435
ELHETEC_4152
ECWEcE24377A_4405
EUNUMNK88_4715
ECPECP_4088
ENAECNA114_3975(yihU)
ECOSEC958_4354(yihU)
ECVAPECO1_2588
ECOAAPECO78_00150
ECXEcHS_A4104
ECMEcSMS35_4267
ECYECSE_4165
ECRECIAI1_4082(yihU)
ECQECED1_4582(yihU)
EUMECUMN_4409(yihU)
ECTECIAI39_3118(yihU)
EOCCE10_4546(yihU)
EBRECB_03767(yihU)
EBLECD_03767(yihU)
EBEB21_03716(yihU)
EBDECBD_4145
ECIUTI89_C4463(yihU)
EIHECOK1_4346
ECZECS88_4324
ECCc4826(yihU)
ELOEC042_4256
ELNNRG857_19350
ESEECSF_3733
ECLEcolC_4139
EKOEKO11_4480
EKFKO11_03195(yihU)
EABECABU_c43810
EDHEcDH1_4104
EDJECDH1ME8569_3753(yihU)
ELUUM146_19610
ELWECW_m4186(yihU)
ELLWFL_20395(yihU)
ELCi14_4419(yihU)
ELDi02_4419(yihU)
ELPP12B_c3997
ELFLF82_610
ECOLLY180_20115
ECOIECOPMV1_04237(garR_4)
ECOJP423_21510
EMAC1192_16095
ESZFEM44_09220(yihU)
STYSTY3855(yihU)
STTt3598(yihU)
SEXSTBHUCCB_37870
SENTTY21A_18195
STMSTM4023(yihU)
SEOSTM14_4836(yihU)
SEVSTMMW_39871
SEYSL1344_3969(yihU)
SEMSTMDT12_C41660
SEJSTMUK_4006(yihU)
SEBSTM474_4200(yihU)
SEFUMN798_4360(yihU)
SETUSTU288_20245
SETCCFSAN001921_20325
SENRSTMDT2_38831(yihU)
SENDDT104_40301(yihU)
SENICY43_21025
SEENSE451236_00795
SPTSPA3864(yihU)
SEKSSPA3594
SPQSPAB_04982
SEISPC_4126(yihU)
SECSCH_3913(yihU)
SEHSeHA_C4346
SHBSU5_0119
SENHCFSAN002069_11975
SEEHSEEH1578_06140
SEESNSL254_A4300
SENNSN31241_47150
SEWSeSA_A4233
SEASeAg_B4255
SENSQ786_19720
SEDSeD_A4411
SEGSG3402(yihU)
SELSPUL_3649(yihU)
SEGASPUCDC_3635(yihU)
SETSEN3811(yihU)
SENAAU38_19695
SENOAU37_19710
SENVAU39_19730
SENQAU40_22020
SENLIY59_20190
SENJCFSAN001992_13600
SEECCFSAN002050_02990
SEEBSEEB0189_022240
SEEPI137_17525
SENBBN855_40890
SENEIA1_19550
SENCSEET0819_03940
SESSARI_03643
SBGSBG_3540(yihU)
SBZA464_4064
SBVN643_17755
SALZEOS98_22210
SFLSF3954(yihU)
SFXS3792(yihU)
SFVSFV_3617(yihU)
SFESFxv_4308(yihU)
SFNSFy_5649
SFSSFyv_5712
SFTNCTC1_04280(yihU)
SSNSSON_4048(yihU)
SBOSBO_3887(yihU)
SHQA0259_00965
ENCECL_05103
ECLGEC036_44050
ECLEECNIH2_23255
ECLNECNIH4_22495
ECLIECNIH5_21760
ECLXLI66_22510
ECLYLI62_24595
ECLZLI64_21625
ECLOENC_00300
EHMAB284_04510
EXFBFV63_21885
ECLAECNIH3_21835
ECLCECR091_21765
EAUDI57_18815
EKBBFV64_23245
ENOECENHK_21935
EECEcWSU1_04480(yihU)
ELGBH714_14860
ECANCWI88_22490
ERNBFV67_21865
ECLSLI67_024265
ECHGFY206_24275(yihU)
EASEntas_4393
LNICWR52_12850
EBGFAI37_07030(yihU)
ENDA4308_06885
ENZG0034_22840(yihU)
ENSHWQ15_07830(yihU)
ENKLOC22_10415(yihU)
EHUD5067_0023105(yihU)
EMORL6Y89_22015(yihU)
ESAESA_04058
CSKES15_0037
CSZCSSP291_18805
CSJCSK29544_00987
CCONAFK62_19810
CSIP262_05706
CMJAFK66_000210
CUIAFK65_19600
CMWAFK63_18745
CTUCTU_41740(yihU)
KLWDA718_29160
KARLGL98_24785(yihU)
KGRJJJ10_27435(yihU)
CROROD_38791
CKOCKO_03131
CFDCFNIH1_06955
CBRAA6J81_16395
CWECO701_21335
CYOCD187_23365
CPOTFOB25_10635(yihU)
CFQC2U38_25190
CSEDJY391_21700(yihU)
CAMAF384_21000
CAFAL524_03835
CIFAL515_02035
CFARCI104_24475
CIRC2U53_10580
CIEAN232_03630
CPARCUC49_19980
CTELGBC03_05230(yihU)
CITZE4Z61_16335(yihU)
CARSE1B03_01740(yihU)
ESCEntcl_1241
LAXAPT61_00220
LEIC2U54_04485
LEEDVA44_23385
LERGNG29_22755(yihU)
LEAGNG26_22095(yihU)
LPNUKQ929_20900(yihU)
LAZA8A57_21395
BAGEBADSM9389_41410
AHNNCTC12129_04955(garR_2)
ASUBNLZ15_21985(yihU)
KINAB182_24960
YALAT01_41
SFWWN53_01445
SFGAV650_24195
SFOZ042_05670
RAHRahaq_4078
RACEJHW33_14720(yihU)
RAQRahaq2_4181
RAAQ7S_20720
RVCJ9880_05845(yihU)
PAMPANA_3497(yihU)
PLFPANA5342_0554(yihU)
PAJPAJ_2726(yihU)
PAQPAGR_g0536
PSTWDSJ_21395
MTHIC7M52_01008(yihU)
HPARAL518_02780
PRAGEKN56_14665
LRINCTC12151_00811(Hgd)
BSUNA4G13_00755
VSIMTO69_14805(yihU)
VSHBSZ05_23595
VSRVspart_03220(hgd)
VGIMID13_22250(yihU)
AEIAOY20_11465
SROSBBH56_04580
THINCRN91_08445
CUHBJN34_35670
BFNOI25_3878
PDIOPDMSB3_2375.1(yihU)
BBHBN112_4333
BBRBB4070
BBMBN115_3759
BBXBBS798_3863
BGMCAL15_12665
AXYAXYL_01396
AISBUW96_19440
ADYHLG70_04255
ACIPCBP36_00930
ACISCBP35_18025
AANTHUK68_04545
ARADKI609_19130
CODOLAD35_04455
ADNAlide_0276
ADKAlide2_0223
DIHG7047_09480
DAERH9K75_01440
ATAAWN88_00520
RHTNT26_p10281
CHELAL346_05120
RBMTEF_16385
PSFPSE_2341(garR)
PHRC6569_18140
PSTGE8M01_11950
RIDRIdsm_01292(hgd_4)
PYEA6J80_20645
NOVTQ38_027345
NOTC7W88_20575
SPKCKC8_02205
SBINSBA_ch1_18910
SPHBEP837_03228
SHUMSTHU_22030
SVCSTVA_25540(garR)
STELSTAQ_18190
ABSAZOBR_p340215
HTQFRZ44_48020(yihU)
HADHFRZ61_45740
NACINUH88_15765
 » show all
Reference
1  [PMID:24463506]
  Authors
Denger K, Weiss M, Felux AK, Schneider A, Mayer C, Spiteller D, Huhn T, Cook AM, Schleheck D
  Title
Sulphoglycolysis in Escherichia coli K-12 closes a gap in the biogeochemical sulphur cycle.
  Journal
Nature 507:114-7 (2014)
DOI:10.1038/nature12947
  Sequence
[eco:b3882]
Reference
2
  Authors
Sharma, M., Abayakoon, P., Lingford, J.P., Epa, R., John, A., Jin, Y., Goddard-Borger, E.D., Davies, G.J. and Williams, S.J.
  Title
Dynamic structural changes accompany the production of dihydroxypropanesulfonate by sulfolactaldehyde reductase.
  Journal
ACS Catalysis 10:2826-2836 (2020)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.373
IUBMB Enzyme Nomenclature: 1.1.1.373
ExPASy - ENZYME nomenclature database: 1.1.1.373
BRENDA, the Enzyme Database: 1.1.1.373

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