KEGG   ENZYME: 1.1.2.6
Entry
EC 1.1.2.6                  Enzyme                                 
Name
polyvinyl alcohol dehydrogenase (cytochrome);
PVA dehydrogenase;
PVADH
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With a cytochrome as acceptor
Sysname
polyvinyl alcohol:ferricytochrome-c oxidoreductase
Reaction(IUBMB)
polyvinyl alcohol + ferricytochrome c = oxidized polyvinyl alcohol + ferrocytochrome c + H+ [RN:R03136]
Reaction(KEGG)
R03136
Substrate
polyvinyl alcohol [CPD:C00980];
ferricytochrome c [CPD:C00125]
Product
oxidized polyvinyl alcohol [CPD:C01166];
ferrocytochrome c [CPD:C00126];
H+ [CPD:C00080]
Comment
A quinoprotein. The enzyme is involved in bacterial polyvinyl alcohol degradation. Some Gram-negative bacteria degrade polyvinyl alcohol by importing it into the periplasmic space, where it is oxidized by polyvinyl alcohol dehydrogenase, an enzyme that is coupled to the respiratory chain via cytochrome c. The enzyme contains a pyrroloquinoline quinone cofactor.
History
EC 1.1.2.6 created 1989 as EC 1.1.99.23, transferred 2010 to EC 1.1.2.6
Orthology
K05889  polyvinyl alcohol dehydrogenase (cytochrome)
Genes
XFAXF_2259
XFTPD_1299
XFNXfasM23_1384
XFFXFLM_00585
XFLP303_06185
XFSD934_06040
XTWAB672_07465
XCCXCC4080
XCBXC_4171
XCAxcc-b100_4282(mxaF2)
XCPXCR_0167
XCVXCV4300
XAXXACM_4071
XACXAC4199
XCIXCAW_00095
XCTJ151_04381
XCJJ158_04334
XCUJ159_04330
XCNJ169_04378
XCWJ162_04336
XCRJ163_04331
XCMJ164_04331
XCFJ172_04371
XFUXFF4834R_chr40700
XAOXAC29_21160
XOMXOO0301(XOO0301)
XOOXOO0329
XOPPXO_02746
XOYAZ54_23465
XORXOC_0353
XOZBE73_22640
XSASB85_06375
XTNFD63_06065
XFRBER92_01075
XVEBJD12_11700
XPEBJD13_17990
XHRXJ27_14710
XGABI317_01715
XPHXppCFBP6546_13360(XppCFBP6546P_13360)
XANAC801_20920
XARXB05_15910
XHYFZ025_21115
XTHG4Q83_12040
XEUXSP_003948
XHDLMG31886_43030(pvaA)
LEMLEN_1815
PAEWKIH87_12105
ZALAZF00_04145
OSGBST96_13570 BST96_14780 BST96_16125
HJABST95_07100
HALCEY643_15230
KIMG3T16_17020
AFUSEYZ66_08615
LSHCAB17_18600
KAKKalk_14285
PSPIPS2015_1317 PS2015_1347
BCTGEM_3393
BANNJFN94_16570
BCAIK788_0004339
DOEDENOEST_0328 DENOEST_1442
EBAp2A321(pvaA)
SURSTAUR_3610
AGEAA314_09129
SCLsce5403
SCUSCE1572_16470 SCE1572_48810
BJAbll5504(bll5504)
BJUBJ6T_42530
BJPRN69_20665
BRADBF49_6141
BRKCWS35_01350
BOTCIT37_26850
BSYMCIT39_18860
BARHWN72_45780
BVZBRAD3257_5552(pvaA)
BELBE61_75900
BSEPHAP48_0010140
BQBJ4P68_0029515
PZUPHZ_c0057
PHBHYN04_08910
NPPPP1Y_Mpl7012
NOTC7W88_18110
SPHPLH20_00830 LH20_22430
SGISGRAN_2681(pvadh)
SWISwit_1323
SPHDHY78_19955
SPPHKFK14_08110
PARJJ4G78_07990
ANHA6F65_02146(pvaA)
ADOA6F68_02640(pvaA)
ERFFIU90_05160(pvaA)
NCBC0V82_25705
PTRIKDC22_18130
NBRO3I_001310
NTPCRH09_14355
NOZDMB37_02095
NAHF5544_04375 F5544_29340
NIEKV110_15645
SPINKV203_18520
SGFHEP81_07900
LSEF1C12_12190
ICAIntca_0327
AGRAAGRA3207_002444 AGRA3207_005569
AMYCCU254_27705
AABA4R43_37700
AMYYYIM_40365(pvaA)
SESPBN6_35770 BN6_42600
SSYIEKG83_15725 EKG83_23805
KPHYAOZ06_12405 AOZ06_38375
LEDBBK82_29305
MCABHXZ27_15905
AIHAiant_25840 Aiant_33000
PLABC6361_22955
PLATC6W10_31785
PSUUPsuf_080790
NFLCOO91_00281
PLONPla110_26560
GMAAciX8_3775
TRSTerro_3165
TALBFTW19_16340
EDAGWR55_16290
SUSAcid_5713
ABACLuPra_02536(pvaA)
FGGFSB75_12825
SLISlin_2985
SPIRCWM47_18820
SPIKEXU85_28000
MSZMSSIH_3519
MSWMSSIT_3580
STOSTK_11640
SOHD1869_04380
MTENGWK48_09485
AMANB6F84_03900
 » show all
Reference
1  [PMID:3513704]
  Authors
Shimao M, Ninomiya K, Kuno O, Kato N, Sakazawa C.
  Title
Existence of a novel enzyme, pyrroloquinoline quinone-dependent polyvinyl alcohol dehydrogenase, in a bacterial symbiont, Pseudomonas sp. strain VM15C.
  Journal
Appl Environ Microbiol 51:268-75 (1986)
DOI:10.1128/AEM.51.2.268-275.1986
Reference
2  [PMID:16347841]
  Authors
Shimao M, Onishi S, Kato N, Sakazawa C.
  Title
Pyrroloquinoline Quinone-Dependent Cytochrome Reduction in Polyvinyl Alcohol-Degrading Pseudomonas sp. Strain VM15C.
  Journal
Appl Environ Microbiol 55:275-278 (1989)
DOI:10.1128/AEM.55.2.275-278.1989
Reference
3  [PMID:18343342]
  Authors
Mamoto R, Hu X, Chiue H, Fujioka Y, Kawai F
  Title
Cloning and expression of soluble cytochrome c and its role in polyvinyl alcohol  degradation by polyvinyl alcohol-utilizing Sphingopyxis sp. strain 113P3.
  Journal
J Biosci Bioeng 105:147-51 (2008)
DOI:10.1263/jbb.105.147
Reference
4  [PMID:16804170]
  Authors
Hirota-Mamoto R, Nagai R, Tachibana S, Yasuda M, Tani A, Kimbara K, Kawai F
  Title
Cloning and expression of the gene for periplasmic poly(vinyl alcohol) dehydrogenase from Sphingomonas sp. strain 113P3, a novel-type quinohaemoprotein alcohol dehydrogenase.
  Journal
Microbiology 152:1941-9 (2006)
DOI:10.1099/mic.0.28848-0
  Sequence
Reference
5  [PMID:18214469]
  Authors
Hu X, Mamoto R, Fujioka Y, Tani A, Kimbara K, Kawai F
  Title
The pva operon is located on the megaplasmid of Sphingopyxis sp. strain 113P3 and is constitutively expressed, although expression is enhanced by PVA.
  Journal
Appl Microbiol Biotechnol 78:685-93 (2008)
DOI:10.1007/s00253-008-1348-y
Reference
6  [PMID:19590867]
  Authors
Kawai F, Hu X
  Title
Biochemistry of microbial polyvinyl alcohol degradation.
  Journal
Appl Microbiol Biotechnol 84:227-37 (2009)
DOI:10.1007/s00253-009-2113-6
Other DBs
ExplorEnz - The Enzyme Database: 1.1.2.6
IUBMB Enzyme Nomenclature: 1.1.2.6
ExPASy - ENZYME nomenclature database: 1.1.2.6
BRENDA, the Enzyme Database: 1.1.2.6

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