KEGG   ENZYME: 1.13.11.20
Entry
EC 1.13.11.20               Enzyme                                 
Name
cysteine dioxygenase;
cysteine oxidase
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
Sysname
L-cysteine:oxygen oxidoreductase
Reaction(IUBMB)
L-cysteine + O2 = 3-sulfinoalanine [RN:R00893]
Reaction(KEGG)
R00893
Substrate
L-cysteine [CPD:C00097];
O2 [CPD:C00007]
Product
3-sulfinoalanine [CPD:C00606]
Comment
Requires Fe2+ and NAD(P)H.
History
EC 1.13.11.20 created 1972, modified 1976
Pathway
ec00270  Cysteine and methionine metabolism
ec00430  Taurine and hypotaurine metabolism
ec01100  Metabolic pathways
Orthology
K00456  cysteine dioxygenase
Genes
HSA1036(CDO1)
PTR462010(CDO1)
PPS100986954(CDO1)
GGO101149842(CDO1)
PON100174398(CDO1)
NLE100594676(CDO1)
MCC696387(CDO1)
MCF101866783(CDO1)
CSAB103244368(CDO1)
CATY105590665(CDO1)
PANU101026914(CDO1)
TGE112625760(CDO1)
RRO104653573(CDO1)
RBB108540010(CDO1)
TFN117065993(CDO1)
PTEH111530358(CDO1)
CJC100407992(CDO1)
SBQ101043153(CDO1)
CSYR103274883(CDO1)
MMUR105870837(CDO1)
OGA100943645(CDO1)
MMU12583(Cdo1)
MCAL110284699(Cdo1)
MPAH110333289(Cdo1)
RNO81718(Cdo1)
MCOC116087135(Cdo1)
MUN110563214(Cdo1)
CGE100760315(Cdo1)
PLEU114710062(Cdo1)
NGI103727417(Cdo1)
HGL101721993(Cdo1)
CPOC100719433(Cdo1)
CCAN109691519(Cdo1)
DSP122102006(Cdo1)
NCAR124987204
OCU100350475(CDO1)
OPI101528796(CDO1)
TUP102489688(CDO1)
CFA474637(CDO1)
VVP112932435(CDO1)
VLG121494429(CDO1)
AML100469964(CDO1)
UMR103679999(CDO1)
UAH113261607(CDO1)
UAR123790444(CDO1)
ELK111158895
LLV125099788
MPUF101672348(CDO1)
ORO101380397(CDO1)
EJU114200494(CDO1)
ZCA113929606(CDO1)
MLX118016544(CDO1)
FCA101090583(CDO1)
PYU121010554(CDO1)
PBG122470871(CDO1)
PTG102953118(CDO1)
PPAD109278920(CDO1)
AJU106978916(CDO1)
HHV120245513(CDO1)
BTA514462(CDO1)
BOM102270124(CDO1)
BIU109564623(CDO1)
BBUB102406101(CDO1)
CHX102190230(CDO1)
OAS101102489(CDO1)
ODA120852633 120860984
CCAD122442962(CDO1)
SSC100312964(CDO1)
CFR102512502(CDO1)
CBAI105082044(CDO1)
CDK105095368(CDO1)
VPC102534745(CDO1)
BACU103006348(CDO1)
LVE103087447(CDO1)
OOR101279789(CDO1)
DLE111183473(CDO1)
PCAD102980591(CDO1)
PSIU116751155(CDO1)
ECB100629132(CDO1)
EPZ103546968(CDO1)
EAI106831470(CDO1)
MYB102241071(CDO1)
MYD102772725(CDO1)
MMYO118656665(CDO1)
MLF102432880(CDO1)
MNA107546520(CDO1)
PKL118703886(CDO1)
HAI109387407(CDO1)
DRO112307227(CDO1)
SHON118977354(CDO1)
AJM119046660(CDO1)
PDIC114497938(CDO1)
PHAS123818021(CDO1)
MMF118642196(CDO1)
RFQ117022872 117024932(CDO1)
PALE102884325(CDO1)
PGIG120590845(CDO1)
PVP105290849(CDO1)
RAY107498159(CDO1)
MJV108404185
TOD119243574(CDO1)
SARA101558641(CDO1)
LAV100661395(CDO1)
TMU101358490
DNM101424234(CDO1)
MDO100015236(CDO1)
GAS123235655(CDO1)
SHR100923840(CDO1)
PCW110194825(CDO1)
OAA100086382(CDO1)
GGA427391(CDO1)
PCOC116236226(CDO1)
MGP100546165(CDO1)
CJO107306663(CDO1)
NMEL110390133(CDO1)
APLA101795836(CDO1)
ACYG106047873(CDO1)
AFUL116501124(CDO1)
TGU100226707(CDO1)
LSR110479145(CDO1)
SCAN103821490(CDO1)
PMOA120512620(CDO1)
OTC121333669(CDO1)
PRUF121349036(CDO1)
GFR102037917(CDO1)
FAB101808832(CDO1)
PHI102111285(CDO1)
PMAJ107216222(CDO1)
CCAE111941192(CDO1)
CCW104690494(CDO1)
ETL114056478(CDO1)
ZAB102065410(CDO1)
FPG101913484(CDO1)
FCH102048692(CDO1)
CLV102083674(CDO1)
EGZ104122487(CDO1)
NNI104009535 104019899(CDO1)
ACUN113489916(CDO1)
TALA104356525(CDO1)
PADL103925718(CDO1)
ACHC115337014(CDO1)
AROW112967871(CDO1)
NPD112958883(CDO1)
DNE112985820(CDO1)
ASN102375863(CDO1)
AMJ102561835(CDO1)
CPOO109323572(CDO1)
GGN109297304(CDO1)
PSS102446722(CDO1)
CMY102940727(CDO1)
CPIC101939943(CDO1)
TST117879286(CDO1)
CABI116829973(CDO1)
MRV120408394(CDO1)
ACS100562760(cdo1)
PVT110072047(CDO1)
SUND121923448(CDO1)
PBI103056518 103061779(CDO1)
PMUR107290893(CDO1)
TSR106545000(CDO1)
PGUT117674663(CDO1)
VKO123031248(CDO1)
PMUA114606118(CDO1)
ZVI118076855(CDO1)
GJA107114713(CDO1)
XLA398963(cdo1.L) 443755(cdo1.S)
XTR394737(cdo1)
NPR108789758(CDO1)
RTEM120931882(CDO1)
BBUF120992590(CDO1)
BGAR122924627(CDO1)
DRE393714(cdo1)
SRX107728256(cdo1) 107729053
SANH107661171(cdo1) 107663593
SGH107572968(cdo1) 107573765
CCAR109082360 109082370
CAUA113052685 113085673 113106915
PPRM120475512(cdo1)
IPU108265901(cdo1)
PHYP113533152(cdo1)
SMEO124400456(cdo1)
TFD113656304(cdo1)
AMEX103041926(cdo1)
EEE113571001(cdo1)
TRU101062049(cdo1)
LCO104920815(cdo1)
NCC104951608(cdo1)
CGOB115014013(cdo1)
ELY117253152(cdo1)
PLEP121944996(cdo1)
SLUC116054151(cdo1)
ECRA117944710(cdo1)
PFLV114555847(cdo1)
GAT120830485(cdo1)
PPUG119224737(cdo1)
MSAM119891642(cdo1)
CUD121510150(cdo1)
MZE101466957(cdo1)
ONL100706226(cdo1)
OAU116328387(cdo1)
OLA101158113(cdo1)
OML112148910(cdo1)
XMA102224539(cdo1)
XCO114155052(cdo1)
XHE116730443(cdo1)
PRET103470089(cdo1)
PFOR103141756(cdo1)
PLAI106959812(cdo1)
PMEI106923060(cdo1)
GAF122827904(cdo1)
CVG107092280(cdo1)
CTUL119798525(cdo1)
GMU124877745(cdo1)
NFU107394154(cdo1)
KMR108233546(cdo1)
ALIM106513669(cdo1)
NWH119413901(cdo1)
AOCE111564699(cdo1)
CSEM103396961 103397636(cdo1)
POV109636953(cdo1)
SSEN122770051(cdo1)
HHIP117767469(cdo1)
LCF108882107(cdo1)
SDU111236527(cdo1)
SLAL111665984(cdo1)
XGL120804632(cdo1)
HCQ109526457(cdo1)
BPEC110172102(cdo1)
MALB109956542(cdo1)
SASA100196492(cdo1) 106580183
OTW112247104 112263417
OMY110525260 110535689
OGO124034637 124035974
ONE115111268(cdo1) 115139699
SALP111957662(cdo1) 111975180
SNH120050314 120063031(cdo1)
ELS105014612(cdo1)
SFM108937964(cdo1)
PKI111856510(cdo1)
AANG118237441(cdo1)
LOC102698527(cdo1)
PSPA121300563 121301124 121302759 121315234
ARUT117401227 117408683 117420481 117962768
LCM102361149(CDO1)
CMK103181130(cdo1) 103183545
RTP109911359(cdo1) 109913399
BFO118411498
BBEL109468940
CIN101242078
SCLV120332958 120333000
SPU575999
APLC110979355
SKO100367224
DMEDmel_CG5493(CG5493)
DER6547019
DSE6609821
DSIDsimw501_GD25380(Dsim_GD25380)
DYADyak_GE13903
DAN6495785
DSR110189663
DPODpse_GA18925
DPE6592903
DMN117185769
DWI6640453
DGR6559745
DMODmoj_GI19578
DAZ108615575
DNV108653491
DHE111603373
DVI6625311
CCAT101461140
BOD106618886
MDE101891450
SCAC106080475
LCQ111684854
AGAAgaP_AGAP005153
ACOZ120950699
AARA120894565
AAG5569163
AALB109425710
CQUCpipJ_CPIJ010456 CpipJ_CPIJ020056
CPII120412636
CNS116352129
AME726371
ACER107998788
ALAB122716094
BIM100743166
BBIF117216288
BVK117231569
BVAN117162025
BTER100644375
BPYO122574271
CCAL108622094
OBB114879976
MGEN117222613
NMEA116428445
CGIG122404830
SOC105207393
MPHA105838922
AEC105153025
ACEP105622888 105625198
PBAR105434257
VEM105564992
HST105191842
DQU106752367
CFO105248721
FEX115244113
LHU105679458
PGC109856511
OBO105277346
PCF106788698
PFUC122514131
VPS122634993
NVI100120916
CSOL105365069
TPRE106648916
MDL103580858
CGLO123264118
FAS105271825
DAM107036297
AGIF122860883
CCIN107272214
TCA663314
DPA109536467
SOY115888999
ATD109595209
CSET123308265
AGB108910564
LDC111518214
NVL108567255
APLN108735111
PPYR116159334
OTU111426632
BMOR101747037
BMAN114251996
MSEX115444542
DPLKGM_201726A
BANY112054455
PMAC106709504
PPOT106101407
PXU106124783
PRAP110993393
ZCE119836408
HAW110374883
TNL113500011
SLIU111349858
OFU114364370
PXY105381613 105392890
API100166473
DNX107166124
AGS114127504
RMD113549948
BTAB109039042
DCI103521032 103522148
CLEC106661510
HHAL106680521
NLU111047156
PHUPhum_PHUM534550
FOC113206449
ZNE110831578
CSEC111864365
FCD110847644 110849514
DPXDAPPUDRAFT_202397
DMK116921698
PVM113815679
PJA122252925
PCHN125047079
HAME121853542
PCLA123766895
PTRU123503266
HAZT108680784
EAF111709395
ISCIscW_ISCW008991
DSV119455267 119455269
RSAN119394456
RMP119172560
VDE111244173
VJA111267559
TUT107363016
DPTE113795934
DFR124493182
CSCU111625899
PTEP107440186
SDM118195079 118195178
CELCELE_F56F10.3(cdo-1)
CBRCBG_20456(Cbr-cdo-1)
NAINECAME_01074
HROHELRODRAFT_187713
LGILOTGIDRAFT_204525
PCAN112557547
BGT106056092 106056093 106063440 106063441 106066992 106066993 106078700 106079456
GAE121373708 121373727
HRF124115427
HRJ124283877
CRG105330874 105339692 105340251
MYI110451032
PMAX117315428
MMER123542809
OBI106883352
OSN115219906
LAK106153182
SMMSmp_165750
OVIT265_02066
NVE5512100
EPA110250971
ATEN116288182
ADF107358195
AMIL114961804
PDAM113679197
SPIS111334623
DGT114522946
XEN124450988
HMG100200077 100204586 100215369
TADTRIADDRAFT_49766
AQU100637150
QSU112020676
CRECHLRE_03g163950v5 CHLRE_03g174400v5
VCNVOLCADRAFT_103087
MNGMNEG_8258
CVRCHLNCDRAFT_134860 CHLNCDRAFT_142389
APROF751_3619
PPAPAS_chr2-2_0322
DHADEHA2E07568g
PICPICST_43654(CDG1)
PGUPGUG_05513
SPAASPAPADRAFT_59145
LELLELG_05361
CALCAALFM_CR09180WA(CDG1)
CTPCTRG_05906
COTCORT_0G01400
CDUCD36_34565
CTENCANTEDRAFT_112917
YLIYALI0F11627g
CLUCLUG_03367
CLUSA9F13_01g08272
CAURCJI97_003777
SLBAWJ20_1285
BNNFOA43_004212
BBRXBRETT_001995
OPAHPODL_00800
NCRNCU06625
NTENEUTE1DRAFT120866(NEUTE1DRAFT_120866)
SMPSMAC_04752
PANPODANSg7426
TTTTHITE_2114893
MTMMYCTH_2298517
MGRMGG_06095
PPEIPpBr36_02922
SSCKSPSK_07920
FGRFGSG_09820 FGSG_13829
FPUFPSE_00821 FPSE_08792
FVRFVEG_06438 FVEG_12228
FOXFOXG_08236 FOXG_13311
NHENECHADRAFT_33014
TRETRIREDRAFT_120176(tr43896)
TRRM419DRAFT_23655
MAJMAA_05067
CMTCCM_04268
PLJVFPFJ_00876
VALVDBG_00920
VDAVDAG_00530
CFJCFIO01_00039
CHIGCH63R_04793
SAPOSAPIO_CDS7122
ELAUCREL1_11606
PFYPFICI_04865 PFICI_05100
SSLSS1G_00064 SS1G_11285
BFUBCIN_03g07140 BCIN_07g00260
MBEMBM_03667 MBM_04259
PSCOLY89DRAFT_598060 LY89DRAFT_695475
GLZGLAREA_03279 GLAREA_12924
ANIAN4081.2
AFMAFUA_1G05570 AFUA_5G14410
ACTACLA_017290 ACLA_029090
NFINFIA_019200 NFIA_072490
AORAO090009000384 AO090020000659
ANGANI_1_2032184(An04g07230) ANI_1_586164(An18g04410)
AFVAFLA_009988 AFLA_010970
ALUCAKAW2_30283A AKAW2_31157A(CDO1)
ACHEACHE_11489A(CDO1)
APUUAPUU_10374S APUU_40268A
PCSPc18g02180 Pc21g04760
PDPPDIP_73910 PDIP_82710
TMFPMAA_024760
TRGTRUGW13939_05343
CIMCIMG_03912
CPWCPC735_004350
UREUREG_02026
PBLPAAG_08649
PBNPADG_01418
ABEARB_05630
TVETRV_06715
AJEHCAG_00220
BGHBDBG_04994
PNOSNOG_11809
PTEPTT_13022
BZECOCCADRAFT_5944
BSCCOCSADRAFT_41333
BORCOCMIDRAFT_84712
AALTCC77DRAFT_1059072
ZTRMYCGRDRAFT_65763
PFJMYCFIDRAFT_149657
FFUCLAFUR5_00637
BCOMBAUCODRAFT_28923
NPAUCRNP2_6189
TMLGSTUM_00004091001
MBRMONBRDRAFT_31344
SREPTSG_11984
DDIDDB_G0287555
DPPDICPUDRAFT_154741
DFADFA_11478
ACANACA1_288020
TGOTGME49_244406
FCYFRACYDRAFT_162827
AAFAURANDRAFT_33800
PIFPITG_02767
PSOJPHYSODRAFT_476031
SPARSPRG_15156 SPRG_15158
EHXEMIHUDRAFT_433165 EMIHUDRAFT_440449
GTTGUITHDRAFT_142979
NGRNAEGRDRAFT_80458
FAUFraau_1775
VCYIX92_17795
VCTJV59_21275
VAQFIV01_19485(cdoA)
FNAOOM_0797
FNLM973_08275
VOKCOSY_0626
CVICV_3182
CVCBKX93_06645
CHROCXB49_05610
CHRIDK842_00800
CHRBDK843_06080
CRZD1345_06315
CHAECH06BL_13780
MXAMXAN_0927
MSDMYSTI_00948
MYMA176_007033
MFBMFUL124B02_05320
CCXCOCOR_08090
MFULILAB_04065 LILAB_08875
MMASMYMAC_007211
SURSTAUR_8399
BSUBSU31140(cdoA)
BSRI33_3198
BSLA7A1_2225
BSHBSU6051_31140(cdoA)
BSYI653_14955
BSUTBSUB_03328(cdoA)
BSULBSUA_03328(cdoA)
BSUSQ433_17015
BSOBSNT_09564(yubC)
BSNBSn5_06425
BSQB657_31140(cdoA)
BSXC663_2966(cdoA)
BSPU712_15470
BSSBSUW23_15120(cdoA)
BAEBATR1942_06735
BHTDIC78_15950
BMOJHC660_29940(cdoA)
BTEQG4P54_15885
BIQAN935_15600
BCABCE_2602
BCBBCB4264_A2559
BTBBMB171_C2289
BTTHD73_3422
BTHRYBT1520_16865
BTHIBTK_16890
BTCCT43_CH2514
BTFYBT020_12880
BTGBTB_c26360(cdoA)
BTHTH175_ch2555
BTHYAQ980_14120
BTROFJR70_06325
BJSMY9_3122
BACYQF06_13875
BACLBS34A_34070(cdoA)
BALMBsLM_3102
BWHA9C19_08790
BITBIS30_05085
BCABEFK13_15945
BMHBMWSH_3470(yubC)
BLEBleG1_3890
BGIBGM20_09650
BONA361_26180
BKOCKF48_02445
HHDHBHAL_1275(yubC)
HMNHM131_02390
FPNABE65_010160 ABE65_019820
BSJUP17_22405
POFGS400_07530
MSEMGMB29_08285
MDGK8L98_12655
BVQFHE72_06315
BBEBBR47_48270(yubC)
BFMBP422_19960
BAGRBA6348_07350
BCHSJNE38_25945
PMSKNP414_06634
PMQPM3016_6265
PMWB2K_31640
PLVERIC2_c17370
PCHIPC41400_13510
LFBC1X05_10555
KPULGXN76_03280
PABSJIR001_28910(cdoA)
MIJMINS_01610
SYXSynWH7803_1053
AMRAM1_6344
PAGHNIES204_30540
MPROBJP34_25690
PLSVT03_32165(cdoA)
GMRGmarT_29540(cdoA)
MRIMal4_02770(cdoA)
PBORBSF38_01713(cdoA)
AGVOJF2_68190
KSTKSMBR1_2238(cdo1)
JETL3J17_09920
ABAAcid345_2687
EDAGWR55_17870
SCORJ3U87_19850
MCOSGM418_16390
MBASALGA_3467
PTQP700755_003581
POACW731_01665
PLITK8354_08995
WIJBWZ20_06090
KANIMCC3317_38240(cdoA)
KBEJ4771_04865
CNREB819_01965
APIBG8C43_04070
CRMK6119_07620 K6119_11970
OHOOweho_2938
CHYDH4K34_16065
 » show all
Reference
1  [PMID:5767301]
  Authors
Lombardini JB, Singer TP, Boyer PD.
  Title
Cystein oxygenase. II. Studies on the mechanism of the reaction with 18oxygen.
  Journal
J Biol Chem 244:1172-5 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 1.13.11.20
IUBMB Enzyme Nomenclature: 1.13.11.20
ExPASy - ENZYME nomenclature database: 1.13.11.20
BRENDA, the Enzyme Database: 1.13.11.20
CAS: 37256-59-0

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