KEGG   ENZYME: 1.13.11.57
Entry
EC 1.13.11.57               Enzyme                                 
Name
gallate dioxygenase;
GalA;
gallate:oxygen oxidoreductase
Class
Oxidoreductases;
Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
Sysname
3,4,5-trihydroxybenzoate:oxygen oxidoreductase
Reaction(IUBMB)
3,4,5-trihydroxybenzoate + O2 = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate [RN:R09565]
Reaction(KEGG)
R09565;
(other) R03550
Substrate
3,4,5-trihydroxybenzoate [CPD:C01424];
O2 [CPD:C00007]
Product
(1E)-4-oxobut-1-ene-1,2,4-tricarboxylate [CPD:C04434]
Comment
Contains non-heme Fe2+. The enzyme is a ring-cleavage dioxygenase that acts specifically on 3,4,5-trihydroxybenzoate to produce the keto-tautomer of 4-oxalomesaconate [1,2].
History
EC 1.13.11.57 created 2011
Pathway
ec00627  Aminobenzoate degradation
ec01120  Microbial metabolism in diverse environments
Orthology
K04099  gallate dioxygenase
Genes
KPNKPN_04051
KPUKP1_5420
KPMKPHS_52210
KPPA79E_0056
KPHKPNIH24_25975
KPZKPNIH27_24960
KPVKPNIH29_25920
KPWKPNIH30_26315
KPYKPNIH31_25390
KPGKPNIH32_27180
KPCKPNIH10_25945
KPQKPR0928_25460
KPTVK055_3415
KPRKPR_0055
KPJN559_0092
KPID364_20710
KPAKPNJ1_00059
KPSKPNJ2_00060
KPXPMK1_01557(galA)
KPBFH42_16645
KPNEKU54_000280
KPNULI86_00280
KPNKBN49_0056(pcaH)
KVAKvar_0048
KPEKPK_0043
KPKA593_10490
KVDKR75_07885
KVQSP68_14485
KQUAVR78_04155
KQVB8P98_00275
KARLGL98_00265
RORRORB6_19035
RAODSD31_00315
CROROD_31621
KASKATP_00600
KLUK7B04_17475
IZHFEM41_02385
EBUCUC76_15870
SPESpro_2096
SMAFD781_1923
SRZAXX16_3206
SERASer39006_020425
SERQCWC46_20430
SERMCLM71_09535
SQUE4343_05725
SFJSAMEA4384070_2156(ligB)
SRHZFO014_00005
SENPKHA73_10630
RAHRahaq_2661
RACEJHW33_03865
RAAQ7S_13255
ROXBV494_03530
RVCJ9880_20285
RBADH2866_00085
EAMEAMY_1944(pcaH)
EAYEAM_1902
EBIEbC_05400
PANSFCN45_11120
TCIA7K98_11200
VFLAL536_10245
VZIG5S32_20255
PCQPcP3B5_13930(galA)
PPUPP_2518(glllA)
PPFPput_3200
PPWPputW619_2030
PPBPPUBIRD1_3165
PPIYSA_00530
PPXT1E_3395
PPUTL483_20160
PPUNPP4_26450
PLULFOB45_15920
PEZHWQ56_20110
PGFJ0G10_16060
PIZLAB08_R36540
PSTTCH92_18130
AVNAvin_31250
AVLAvCA_31250
AVDAvCA6_31250
ATNFM020_08445
SYKKDN34_01905
ALRDS731_01180
CSACsal_0323
MPRIMP3633_1414
MFOIJSY38_07135
VFFVITFI_CDS3502
PSENH8B_2725
AMAHDLM_2050
RSLRPSI07_mp1412
RSYRSUY_46170(galA)
RSGJK151_11985
RMERmet_3709
CCAMM5D45_26480
BURBcep18194_C7572
BCENDM39_6585
BCEOI35_7835
BMJBMULJ_05486(ligB)
BMUBmul_6041
BMKDM80_6492
BMULNP80_5253
BCEDDM42_7336(ligB)
BUBBW23_4779
BDFWI26_29680
BTEIWS51_29490
BPSLWS57_17850
BGDbgla_2g01750
BGOBM43_6953(ligB)
BYIBYI23_D009710
BUEBRPE67_DCDS11760
BGPBGL_2c21000(ligB)
BPLAbpln_2g21110
BPHBphy_6377
BCAIK788_0005435
PHSC2L64_29345
PTERC2L65_19030
PTROG5S35_16940
PGISI6I06_24895
PACPFAZ97_23230 FAZ97_33705
PACSFAZ98_26605 FAZ98_29000 FAZ98_34045
BUOBRPE64_DCDS10470
BOJCBF45_06980
CDNBN940_06091
ACKC380_00245
ACRABSY15_1204(ligA)
VEIVeis_0170
VPEVarpa_2578
VPDVAPA_2c01480
VAMC4F17_02070
CTESO987_18260
CKEB5M06_09345
OTKC6570_16450(ligA)
DIHG7047_15145
ATERMW290_13930
HHFE2K99_06675
MASWAM586_11765
MFYHH212_24595
MALIEYF70_25860
MUMFCL38_23490
MFLAGO485_19000
DUGHH213_29575
RGUA4W93_03465
XYKGT347_11010
URUDSM104443_02505(galA)
THUAC731_013745
BEBABWI17_14460
BRABRADO1853(ligB)
BBTBBta_2174(ligB)
PHLKKY_2539
PSINCAK95_21930
PSTGE8M01_02555
AEXAstex_2404
PGVSL003B_1110
NREBES08_28870
SSYSLG_03330(desB)
ALBAEB_P3471
AAYWYH_03044(galA)
RGIRGI145_21125
ROSCTJ15_00885
RMUCFOB66_01800
MAGXXM1_1091
MAGNWV31_13615
PARHI5S86_11495
CCYCSCMU_02410(pcmA)
SLAUSLA_7098
SHUNDWB77_01945(ligB_1)
KSKKSE_75140(pcmA)
KITCFP65_0440
MHOSCXR34_05670(ligA)
MOOBWL13_00076(ligB)
ARTArth_4373
ARTPE5206_14135
APNAsphe3_42380
PEIH9L10_00565(ligA)
ACTNL083_1495
 » show all
Reference
1  [PMID:16030014]
  Authors
Nogales J, Canales A, Jimenez-Barbero J, Garcia JL, Diaz E
  Title
Molecular characterization of the gallate dioxygenase from Pseudomonas putida KT2440. The prototype of a new subgroup of extradiol dioxygenases.
  Journal
J Biol Chem 280:35382-90 (2005)
DOI:10.1074/jbc.M502585200
Reference
2  [PMID:21219457]
  Authors
Nogales J, Canales A, Jimenez-Barbero J, Serra B, Pingarron JM, Garcia JL, Diaz E
  Title
Unravelling the gallic acid degradation pathway in bacteria: the gal cluster from Pseudomonas putida.
  Journal
Mol Microbiol 79:359-74 (2011)
DOI:10.1111/j.1365-2958.2010.07448.x
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 1.13.11.57
IUBMB Enzyme Nomenclature: 1.13.11.57
ExPASy - ENZYME nomenclature database: 1.13.11.57
UM-BBD (Biocatalysis/Biodegradation Database): 1.13.11.57
BRENDA, the Enzyme Database: 1.13.11.57

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