Acting on single donors with incorporation of molecular oxygen (oxygenases);
With incorporation of two atoms of oxygen
3-(4-hydroxy-3-prenylphenyl)pyruvate:oxygen 1,2-oxidoreductase (4-hydroxy-3-prenylmandelate-forming)
3-(4-hydroxy-3-prenylphenyl)pyruvate + O2 = 4-hydroxy-3-prenylmandelate + CO2 [RN:
Requires non-heme-iron(II). Isolated from the bacterium Streptomyces roseochromogenes DS 12976. A bifunctional enzyme involved in clorobiocin biosynthesis that also catalyses the activity of EC
, 4-hydroxy-3-prenylbenzoate synthase.
EC 18.104.22.168 created 2017
ec01110 Biosynthesis of secondary metabolites
K12708 4-hydroxy-3-prenylphenylpyruvate oxygenase / 4-hydroxy-3-prenylbenzoate synthase
Pojer F, Kahlich R, Kammerer B, Li SM, Heide L.
CloR, a bifunctional non-heme iron oxygenase involved in clorobiocin biosynthesis.