Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
protopanaxadiol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating)
protopanaxadiol + [reduced NADPH---hemoprotein reductase] + O2 = protopanaxatriol + [oxidized NADPH---hemoprotein reductase] + H2O [RN:
[reduced NADPH---hemoprotein reductase] [CPD:
[oxidized NADPH---hemoprotein reductase] [CPD:
A cytochrome P-450 (heme-thiolate) protein isolated from the rhizomes of ginseng (Panax ginseng). Involved in the biosynthetic pathway of ginsenosides.
EC 126.96.36.199 created 2013 as EC 188.8.131.52, transferred 2018 to EC 184.108.40.206
ec00999 Biosynthesis of various plant secondary metabolites
ec01110 Biosynthesis of secondary metabolites
K20546 protopanaxadiol 6-hydroxylase
Yue CJ, Zhou X, Zhong JJ
Protopanaxadiol 6-hydroxylase and its role in regulating the ginsenoside heterogeneity in Panax notoginseng cells.
Han JY, Hwang HS, Choi SW, Kim HJ, Choi YE
Cytochrome P450 CYP716A53v2 catalyzes the formation of protopanaxatriol from protopanaxadiol during ginsenoside biosynthesis in Panax ginseng.