KEGG   ENZYME: 1.14.19.76
Entry
EC 1.14.19.76               Enzyme                                 
Name
flavone synthase II;
CYP93B16 (gene name);
CYP93G1 (gene name);
FNS II
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
Sysname
flavanone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (flavone-forming)
Reaction(IUBMB)
a flavanone + [reduced NADPH---hemoprotein reductase] + O2 = a flavone + [oxidized NADPH---hemoprotein reductase] + 2 H2O [RN:R12276]
Reaction(KEGG)
Substrate
flavanone [CPD:C00766];
[reduced NADPH---hemoprotein reductase] [CPD:C03024];
O2 [CPD:C00007]
Product
flavone [CPD:C15608];
[oxidized NADPH---hemoprotein reductase] [CPD:C03161];
H2O [CPD:C00001]
Comment
A cytochrome P-450 (heme-thiolate) protein found in plants. The rice enzyme channels flavanones to the biosynthesis of tricin O-linked conjugates. cf. EC 1.14.20.5, flavone synthase I.
History
EC 1.14.19.76 created 2018
Pathway
ec00941  Flavonoid biosynthesis
ec00943  Isoflavonoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K23179  flavone synthase II
K23180  flavone synthase II
Genes
CIT102609972 102611200
CICCICLE_v10019810mg CICLE_v10019811mg
PVY116113484 116113521 116129556 116145436
MINC123203073
TCC18593008 18593084
GRA105781200
GHI107895096 107919519
GAB108462515 108463531
DZI111284583 111315053
EGR104432774 104432776
GMX100783503(FNSII-1) 100784036(FNSII-2)
GSJ114379343
PVUPHAVU_011G068100g
VAR108323455
VUN114169631
CCAJ109798920
APRC113857422 113859174
MTR25485387 25492470 25492471
CAM101511254
ADU107477091
AIP107634112
AHF112736589 112768987
LANG109351612 109351614
RCU8286099 8286101
HBR110637536 110639710 110670394
MESC110613186 110625897
POP18098816 7473876
PEU105124985
PALZ118053247
SIND105170377
OEU111402974
EGT105949064 105949083
SSPL121740953 121743927
HAN110873193
ECAD122587139
LSV111905568
CCAV112518085
CSIN114286595 114296673 114307649 114322163
OSA4334886
DOSAOs04t0101400-01(Os04g0101400)
OBR102714554 102716963
BDI100841298
ATS109733276
TDC119352891 119361919
TAES123043285 123051157 123187112
TUA125535225
SBI8056944
ZMA103641445 103642652 103646891
SITA101761949
SVS117862541
PVIR120639519 120639522 120681960
PHAI112900040
 » show all
Reference
1  [PMID:10652133]
  Authors
Martens S, Forkmann G
  Title
Cloning and expression of flavone synthase II from Gerbera hybrids.
  Journal
Plant J 20:611-8 (1999)
DOI:10.1046/j.1365-313X.1999.00636.x
  Sequence
Reference
2  [PMID:20132953]
  Authors
Fliegmann J, Furtwangler K, Malterer G, Cantarello C, Schuler G, Ebel J, Mithofer A
  Title
Flavone synthase II (CYP93B16) from soybean (Glycine max L.).
  Journal
Phytochemistry 71:508-14 (2010)
DOI:10.1016/j.phytochem.2010.01.007
  Sequence
[gmx:100783503]
Reference
3  [PMID:24843076]
  Authors
Lam PY, Zhu FY, Chan WL, Liu H, Lo C
  Title
Cytochrome P450 93G1 Is a Flavone Synthase II That Channels Flavanones to the Biosynthesis of Tricin O-Linked Conjugates in Rice.
  Journal
Plant Physiol 165:1315-1327 (2014)
DOI:10.1104/pp.114.239723
  Sequence
[osa:4334886]
Other DBs
ExplorEnz - The Enzyme Database: 1.14.19.76
IUBMB Enzyme Nomenclature: 1.14.19.76
ExPASy - ENZYME nomenclature database: 1.14.19.76
BRENDA, the Enzyme Database: 1.14.19.76

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