KEGG   ENZYME: 1.2.1.54
Entry
EC 1.2.1.54                 Enzyme                                 
Name
gamma-guanidinobutyraldehyde dehydrogenase;
alpha-guanidinobutyraldehyde dehydrogenase;
4-guanidinobutyraldehyde dehydrogenase;
GBAL dehydrogenase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
Sysname
4-guanidinobutanal:NAD+ 1-oxidoreductase
Reaction(IUBMB)
4-guanidinobutanal + NAD+ + H2O = 4-guanidinobutanoate + NADH + 2 H+ [RN:R03177]
Reaction(KEGG)
R03177
Substrate
4-guanidinobutanal [CPD:C02647];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
4-guanidinobutanoate [CPD:C01035];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the degradation of arginine in Pseudomonas putida (cf. EC 1.2.1.19 aminobutyraldehyde dehydrogenase).
History
EC 1.2.1.54 created 1989
Pathway
ec00330  Arginine and proline metabolism
ec01100  Metabolic pathways
Orthology
K12254  4-guanidinobutyraldehyde dehydrogenase / NAD-dependent aldehyde dehydrogenase
Genes
SLQM495_12010
XALXALC_2105
XSASB85_04725
XTNFD63_11895
XHYFZ025_01015
XTHG4Q83_09765
SMLSmlt1571(aldH)
SMTSmal_1330
BUJBurJV3_1321
SMZSMD_1402(aldH)
STEKAXG53_02925
SLMBIZ42_15785
STENCCR98_07065
STEMCLM74_07570
STESMG068_06680
SINCDAIF1_14150(puuC)
SPAQSTNY_R14500
PSUPsesu_2109
PSUWWQ53_02590
PSDDSC_07485
PMEXH4W19_01045
PJPLAG73_10865
PDDMNQ95_01565
XBAC7S18_09045
VNAPN96_08640
VEJVEJY3_04415
VBRA6E01_17925
VSHBSZ05_23820
PAEPA5312
PAEVN297_5492
PAEIN296_5492
PAUPA14_70140(aldH)
PAPPSPA7_6087
PAGPLES_57071
PAFPAM18_5432
PNCNCGM2_6076(aldH)
PAEBNCGM1900_6154(aldH)
PDKPADK2_28295
PSGG655_27960
PRPM062_27985
PAEPPA1S_28715
PAERPA1R_gp3244
PAEMU769_29220
PAELT223_29175
PAESSCV20265_6037
PAEUBN889_05891
PAEGAI22_05275
PAECM802_5490
PAEOM801_5357
PMYPmen_0237
PMKMDS_0290
PREPCA10_27210 PCA10_49530 PCA10_55150
PPSEBN5_0159
PFUWKF707C_14160 KF707C_55600
PALCA0T30_00975
PCQPcP3B5_54750(puuC_3) PcP3B5_60480(puuC_4)
PMUIG4G71_03995 G4G71_07100 G4G71_18480
PPUPP_5278(kauB)
PPFPput_5188
PPGPputGB1_5330
PPWPputW619_0192
PPTPPS_2244 PPS_5130
PPBPPUBIRD1_5072
PPIYSA_04677
PPXT1E_2789
PPUHB479_26140
PPUTL483_31550
PPUNPP4_53430
PPUDDW66_2502 DW66_5700
PFVPsefu_0701 Psefu_1405
PMONX969_09550 X969_25350
PMOTX970_09210 X970_24985
PMOSO165_022555
PPJRK21_02588 RK21_04912
PORAPT59_12895 APT59_20985
PMOLCLJ08_13550
PSTPSPTO_0092
PSBPsyr_0227
PSYRN018_00480
PSPPSPPH_0215
PSAVPSA3335_25755
PAMGBKM19_002630
PCIPCH70_01610
PAVLBKM03_00625
PVDCFBP1590_0205(puuC)
PCABJGS08_00095
PCOFPOR16_00110
PTREI9H09_00100
PSYIMME58_00795
PFLPFL_6046
PPRCPFLCHA0_c24080(puuC1) PFLCHA0_c60050(puuC4)
PPROPPC_2386 PPC_5999
PFEPSF113_5754
PFNHZ99_16915
PFOPfl01_2123 Pfl01_5534(aldH)
PFSPFLU_5976(aldH)
PFCPflA506_5260
PPZH045_20190
PFBVO64_2867
PMANOU5_3622 OU5_5944
PTVAA957_15240
PCGAXG94_14440
PVRPverR02_14435 PverR02_30560
PAZOAYR47_06040
POIBOP93_25560
PRXHRH33_00080
PMEDE3Z27_27465
PFWPF1751_v1c53900
PFFPFLUOLIPICF709040
PFXA7318_26575
PENPSEEN5424(aldH)
PLULFOB45_23600
PBAPSEBR_a2310 PSEBR_a5516
PBCCD58_28845
PPUUPputUW4_03104(puuC1) PputUW4_05318
PDRH681_24150
PSVPVLB_25000
PSKU771_30880
PKCPKB_5073(puuc3) PKB_5650(puuc5)
PCHEY04_10805 EY04_30395
PCZPCL1606_01530 PCL1606_38200
PCPJM49_01075 JM49_19095
PFZAV641_00450
PLQAA042_09885
PALKPSAKL28_42000 PSAKL28_51430 PSAKL28_51610
PRHLT40_16840
PSWLK03_05475
PPVNJ69_18350
PSESPSCI_1602 PSCI_2655
PSEMTO66_11630 TO66_30790
PSECCCOS191_5174(puuC3)
PPSYAOC04_20625
PSOSPOS17_2330 POS17_6003
PKRAYO71_00935 AYO71_19055
PFKPFAS1_11970 PFAS1_28370
PANRA7J50_5711
PPSLBJP27_05655 BJP27_15490
PSETTHL1_5607
PSILPMA3_16500 PMA3_26340 PMA3_29440
PYMAK972_6098
PKEDLD99_11280 DLD99_28095
PALLUYA_01070
PUMHGP31_00075 HGP31_17740
POJPtoMrB4_01710
PGGFX982_01624
PPSHG5J76_03680 G5J76_23635
PGYAWU82_07295 AWU82_18205
PLALFXN65_27120
PSEJHNQ25_00150
PVKEPZ47_28935
PEZHWQ56_01085
PBZGN234_19120
PKHJLK41_01080
PTYJWV26_11845
PMAOPMYSY11_4277(puuC)
PATAJWU58_01495 JWU58_11215
PDWBV82_2161 BV82_2182
PZEHU754_000100 HU754_012300
PMOEHV782_000100 HV782_017720
PCAMHNE05_18800
PSEPC4K39_2239 C4K39_3616
PVWHU752_000120 HU752_022010
PTRTHU722_0000080
PXAKSS93_02605
PSAMHU731_015175
PTZHU718_000080 HU718_018450
PQIKH389_26480
PSHHHU773_000080
PXNHU772_024300
PHVHU739_006950 HU739_018615
PPRGHU725_013470 HU725_013520 HU725_022255
PNNKEM63_00705
PANHHU763_023980
PASGKSS96_00080
PFAKKSS94_26470
PMUYKSS95_03685
PMAMKSS90_24850
PAZEKSS91_00080 KSS91_17130
PALVKSS97_00095 KSS97_16895
PPHABVH74_02395 BVH74_04525
PORYEJA05_27470
PWZJ7655_01500
PTKEXN22_00850 EXN22_00945
PTWTUM18999_01970
PZAHU749_000080
PIEHU724_000095 HU724_017445
PWYHU734_000270
PTAENCTC10697_00088(puuC_1)
PGFJ0G10_00080 J0G10_18400
PCAVD3880_03855 D3880_21725
PJUL1P09_24630
PSAPST_0046
PSZPSTAB_0055
PSRPSTAA_0048
PSCA458_21210
PSJPSJM300_18690
PSHPsest_4305
PSTUUIB01_21885
PSTTCH92_21230
PSEDDM292_18945
PCHLLLJ08_20635
PBMCL52_00880
PKGLW136_22230
AVNAvin_48030(aldH)
AVLAvCA_48030(aldH)
AVDAvCA6_48030(aldH)
ACXAchr_37390(aldH)
PAGRE2H98_17455
HAESLO767_18120
THAPFNC98_01145
ASQAVL57_01780
AAWAVL56_00590
ALEAV939_00595
ALZAV940_00595
LALAT746_07175
AGZM0C34_01445
FBLFbal_1146
SAGAM5M_11425
OSGBST96_18805
MTHDA3224_14415
MICCAUP74_00575(puuC)
MAGAMag101_02170
MIIBTJ40_20510
MICTFIU95_19470(puuC)
MHYDGTQ55_02575
MCELLPW13_13965
MICZGL2_16830
HJABST95_16365
BLEPAL038_06330
HNAHneap_2372
HAZA9404_08905
HCSFF32_03760
HHUAR456_12110
HCOLOKO_02562(puuC)
HSIBOX17_02020
HALOBWR19_12470
HBEBEI_1148
HAFC8233_07745
HALKCUU95_08400
HOLHORIV_63030
HCAMI4484_13715
HSXHNO51_13400 HNO51_13435
HSVHNO53_13995 HNO53_14025
HTXEKK97_15095 EKK97_15120
CMAIBFX80_13800
CAMHLCW13_03445
PAURFGL86_02075
MMWMmwyl1_3527
MMEMarme_3789
MPRIMP3633_0006
MARDIBG28_15415
MFOIJSY38_09295
MPRFJ8N69_08015
AJPAMJAP_2131(kauB)
GSNYC6258_05871
RFOREIFOR_00600(puuC)
AHYAHML_01190
AHDAI20_18260
AHRV428_01300
AHPV429_01300
AHJV469_22020
AHHRY45_01495
AHIVU14_21275
AAJBOQ57_01100
ASAASA_4155
AEOO23A_p3467
AVRB565_3831
AVOAMS64_22450
AMEDB224_5460
ASRWL1483_1298(puuC)
ADHCK627_04995
ACAVVI35_20215
AEMCK911_16265
AEAC2U39_00445
ARVC7N77_03345
AESC2U30_15490
AELNCTC12917_04090(puuC)
ASIMFE240_16545
AALLI6G90_16870
AJDI6H43_09870
ARIVKYK33_00735
OCEGU3_00195
ZDFAN401_16830
VFFVITFI_CDS2202
BMKDM80_3359
PLGNCTC10937_00050(puuC_1)
HYFDTO96_100783(puuC)
RSBRS694_08970
RHGEXZ61_10805
HYBQ5W_22305
HYLLPB072_14535
HYCE5678_17025
HPSEHPF_00630(puuC)
HYNF9K07_01105
HTNKI616_00570
CBABSMCB_2218
PBHAAW51_2992(puuC)
KIAG8A07_16370
METPC1M51_18070
JAGGJA_494
JAZYQ44_01245
JALBZG29_26390
JSVCNX70_26655
JASFJQ89_15855
JLVG3257_27055
MNRACZ75_21885
MASWAM586_25595
MASSCR152_10820
MASZC9I28_04250
MASYDPH57_17665
MALIEYF70_00885
MUMFCL38_17665
MFLAGO485_13095
MPLIE1742_13605
MANCIV454_04605
DUGHH213_07950
UPVEJN92_19140 EJN92_19890
UPIEJG51_002325
LCHLcho_1737
TINTint_0186
RGERGE_26320(aldH)
RBNRBXJA2T_08640
MIUABE85_07415
RGUA4W93_11120
AONDEH84_16845
TTWLCC91_12220
IDCLRM40_09610
ATERMW290_01440 MW290_13085
MPAUZMTM_12870
SNIVSFSGTM_03300
NIVJY500_13490
MESRFGU64_15350
PHTBLM14_27650
KMNHW532_02065
SIXBSY16_55
EADOV14_b1223
ARAArad_8305(dhaL)
SOJK6301_18370
METM446_3859
AALAIGS74_16035
NOHG5V57_27715
HATRC74_13670
RSHRsph17029_3176
RSQRsph17025_2836
RSKRSKD131_3700
RCPRCAP_rcc02448(aldH2)
PKDF8A10_04085
CBOTATE48_09385
NOTC7W88_16550
SECHB18_09235
RCERC1_1452(puuC)
RPMRSPPHO_00962
HJOAY555_10510
HTQFRZ44_30230 FRZ44_49550
HADHFRZ61_17290 FRZ61_48100
TXITH3_10790
THACCSC3H3_10525
TIIDY252_13700
ECOGFIV45_11445 FIV45_12470
PARHI5S86_01675 I5S86_17340
CLBClo1100_0596
MDFK0O62_08615
SVLStrvi_4312
SRCM271_03755
SMALSMALA_7627
SCHACP983_06230
SVDCP969_21125
RLARhola_00000830
ASOIMTP13_00115
LLUTK1X41_04045
NAROCFH99_04475
TBITbis_1741
AMNRAM_31850
AMMAMES_6118(puuC)
AMZB737_6118(puuC)
RRDRradSPS_2074
 » show all
Reference
1
  Authors
Yorifuji, T., Koike, K., Sakurai, T. and Yokoyama, K.
  Title
4-Aminobutyraldehyde and 4-guanidinobutyraldehyde dehydrogenases for arginine degradation in Pseudomonas putida.
  Journal
Agric Biol Chem 50:2009-2016 (1986)
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.54
IUBMB Enzyme Nomenclature: 1.2.1.54
ExPASy - ENZYME nomenclature database: 1.2.1.54
BRENDA, the Enzyme Database: 1.2.1.54
CAS: 56831-75-5

DBGET integrated database retrieval system