KEGG   ENZYME: 1.3.3.17
Entry
EC 1.3.3.17                 Enzyme                                 
Name
benzylmalonyl-CoA dehydrogenase;
iaaF (gene name)
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With oxygen as acceptor
Sysname
benzylmalonyl-CoA:oxygen oxidoreductase (decarboxylating)
Reaction(IUBMB)
benzylmalonyl-CoA + O2 = (E)-cinnamoyl-CoA + CO2 + H2O2 [RN:R12966]
Reaction(KEGG)
R12966
Substrate
benzylmalonyl-CoA [CPD:C22487];
O2 [CPD:C00007]
Product
(E)-cinnamoyl-CoA [CPD:C16256];
CO2 [CPD:C00011];
H2O2 [CPD:C00027]
Comment
The enzyme, characterized from the bacterium Aromatoleum aromaticum, is involved in degradation of (indol-3-yl)acetate, where it is believed to function on (2-aminobenzyl)malonyl-CoA.
History
EC 1.3.3.17 created 2022
Orthology
K25759  benzylmalonyl-CoA dehydrogenase
Genes
EBAebA2055
ABREpbN1_13100
APETToN1_50380
AZIAzCIB_1785
TCLTchl_1907
TAKTharo_2545
DDZDSYM_16420
RPERPE_3222
MAGXXM1_2483
Reference
1  [PMID:34059946]
  Authors
Schuhle K, Saft M, Vogeli B, Erb TJ, Heider J.
  Title
Benzylmalonyl-CoA dehydrogenase, an enzyme involved in bacterial auxin degradation.
  Journal
Arch Microbiol 203:4149-4159 (2021)
DOI:10.1007/s00203-021-02406-3
  Sequence
[eba:ebA2055]
Other DBs
ExplorEnz - The Enzyme Database: 1.3.3.17
IUBMB Enzyme Nomenclature: 1.3.3.17
ExPASy - ENZYME nomenclature database: 1.3.3.17
BRENDA, the Enzyme Database: 1.3.3.17

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